Basic Information:

  VIRBase ID:  

HHID00109408

  Virus:  

Severe acute respiratory syndrome-related coronavirus (SARS)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-206:  MIMAT0000462          LINC01531:  NR_040046     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-206	LINC01531
miRBase Accession/Entrez ID	MIMAT0000462	100128682
Organism	Homo sapiens	Homo sapiens
Category	miRNA	lncRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-206	rs1377769915 chr6:52144418    T/C rs1444614734 chr6:52144412    G/C rs529520481 chr6:52144422    G/T rs761212265 chr6:52144417    G/T rs764617948 chr6:52144414    A/C rs767863130 chr6:52144401    T/A rs767863130 chr6:52144401    T/C rs775920179 chr6:52144406    T/C

Resource	Symbol	SNP ID	SNP Position	Ref/Alt	PMID
LincSNP 3.0	LINC01531	rs12979319 chr19:35407957 C/T         20663923 rs10420543 chr19:35407016 C/T         22504419 rs16970295 chr19:35412804 A/C         22504419 rs16970297 chr19:35412951 A/G         22504419 rs16970299 chr19:35414500 C/T         22504419 rs16970300 chr19:35415591 A/G         22504419 rs8112413 chr19:35419102 G/T         22504419 rs6510485 chr19:35418055 A/G         22504419 rs7249804 chr19:35417914 C/G         22504419 rs12978242 chr19:35400352 G/A         23233662 rs7260133 chr19:35399532 G/C         23233662

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LINC01531	chr19:35900215-35900216(+) m6A exon//intron       - chr19:35900265-35900266(+) m6A exon//intron       - chr19:35900274-35900275(+) m6A exon//intron       - chr19:35900287-35900288(+) m6A exon//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-206	Exosome Primary ovarian tumor cells|Serum     18589210 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Blood|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849
	LINC01531	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-206	Cholesterol 5997 Drug interaction    RC00003325 Vorinostat 5311 Drug interaction    RC00003324 Eloxatine 5310940 Drug interaction    RC00003331 Paroxetine 43815 Drug interaction    RC00003329 Paclitaxel 36314 Drug interaction    RC00003328 5-Fluorouracil 3385 Drug interaction    RC00003323 Doxorubicin 31703 Drug interaction    RC00003327 Bromocriptine 31101 Drug interaction    RC00003326 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00003322 Verapamil 2520 Drug interaction    RC00003321 Sorafenib 216239 Drug interaction    RC00003330

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-206	Irinotecan       60838 Topotecan       60700 Paclitaxel       36314 Sorafenib       216239 Dovitinib       135398510 Crizotinib       11626560

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-206
Interactor2: LINC01531

Evidence Support:

Prediction-Evidence	miRTarBase//miRWalk
Support Database	ViRBase

References:

PMID	33475497	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	Our data revealed that 709 miRNAs target these mRNAs, among which 145 functional MTIs were found and were subsequently selected as the most important interactions for further examination.