Basic Information:

  VIRBase ID:  

HHID00109224

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548am-5p:  MIMAT0022740          LRRTM3:  NM_178011     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548am-5p	LRRTM3
miRBase Accession/Entrez ID	MIMAT0022740	347731
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548am-5p	rs1023899452 chrX:16627065    G/T rs1319380894 chrX:16627063    C/G rs181147953 chrX:16627076    T/G rs768483765 chrX:16627055    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	LRRTM3	chr10:68725061(+) A-I      intronic chr10:68725046(+) A-I      intronic chr10:68725066(+) A-I      intronic chr10:68725062(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LRRTM3	chr10:68685770-68685771(+) m6A 5'UTR       24981863 chr10:68685785-68685786(+) m6A 5'UTR       24981863 chr10:68685899-68685900(+) m6A 5'UTR       - chr10:68685919-68685920(+) m6A 5'UTR       - chr10:68687209-68687210(+) m6A CDS       25456834 chr10:68687225-68687226(+) m6A CDS       25456834 chr10:68687233-68687234(+) m6A CDS       25456834 chr10:68687291-68687292(+) m6A CDS       25456834 chr10:68687300-68687301(+) m6A CDS       25456834 chr10:68687647-68687648(+) m6A CDS       - chr10:68687743-68687744(+) m6A CDS       - chr10:68687849-68687850(+) m6A CDS       - chr10:68687895-68687896(+) m6A CDS       - chr10:68688071-68688072(+) m6A CDS       25456834 chr10:68688125-68688126(+) m6A CDS       25456834 chr10:68688141-68688142(+) m6A CDS       25456834 chr10:68688170-68688171(+) m6A CDS       25456834 chr10:68772049-68772050(+) m6A exon//intron       25456834 chr10:68857421-68857422(+) m6A CDS//exon       25456834//22575960 chr10:68857473-68857474(+) m6A CDS//exon       25456834//22575960 chr10:68857485-68857486(+) m6A CDS//exon       25456834//22575960 chr10:68857495-68857496(+) m6A CDS//exon       25456834//22575960 chr10:68857538-68857539(+) m6A CDS//exon       25456834//22575960 chr10:68857587-68857588(+) m6A 3'UTR//exon       - chr10:68857604-68857605(+) m6A 3'UTR//exon       - chr10:68857633-68857634(+) m6A 3'UTR//exon       - chr10:68857642-68857643(+) m6A 3'UTR//exon       - chr10:68857647-68857648(+) m6A 3'UTR//exon       - chr10:68857652-68857653(+) m6A 3'UTR//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548am-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Urine     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548am-5p
Interactor2: LRRTM3

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.