Basic Information:

  VIRBase ID:  

HHID00109202

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548am-5p:  MIMAT0022740          WDR26:  NM_025160     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548am-5p	WDR26
miRBase Accession/Entrez ID	MIMAT0022740	80232
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CDW2//GID7//MIP2//SKDEAS

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548am-5p	rs1023899452 chrX:16627065    G/T rs1319380894 chrX:16627063    C/G rs181147953 chrX:16627076    T/G rs768483765 chrX:16627055    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	WDR26	chr1:224602484(-) A-I      intronic chr1:224582375(-) A-I      intronic chr1:224591476(-) A-I      intronic chr1:224591491(-) A-I      intronic chr1:224591490(-) A-I      intronic chr1:224591482(-) A-I      intronic chr1:224590958(-) A-I      intronic chr1:224590949(-) A-I      intronic chr1:224590927(-) A-I      intronic chr1:224590923(-) A-I      intronic chr1:224590922(-) A-I      intronic chr1:224582434(-) A-I      intronic chr1:224582390(-) A-I      intronic chr1:224582381(-) A-I      intronic chr1:224577930(-) A-I      intronic chr1:224590933(-) A-I      intronic chr1:224577990(-) A-I      intronic chr1:224577997(-) A-I      intronic chr1:224591527(-) A-I      intronic chr1:224591025(-) A-I      intronic chr1:224582315(-) A-I      intronic chr1:224590967(-) A-I      intronic chr1:224590957(-) A-I      intronic chr1:224590892(-) A-I      intronic chr1:224578026(-) A-I      intronic chr1:224590860(-) A-I      intronic chr1:224588539(-) A-I      intronic chr1:224588359(-) A-I      intronic chr1:224588300(-) A-I      intronic chr1:224587636(-) A-I      intronic chr1:224584925(-) A-I      intronic chr1:224584545(-) A-I      intronic chr1:224584449(-) A-I      intronic chr1:224584443(-) A-I      intronic chr1:224582335(-) A-I      intronic chr1:224584426(-) A-I      intronic chr1:224582470(-) A-I      intronic chr1:224578041(-) A-I      intronic chr1:224578064(-) A-I      intronic chr1:224613728(-) A-I      intronic chr1:224578114(-) A-I      intronic chr1:224578426(-) A-I      intronic chr1:224578001(-) A-I      intronic chr1:224579291(-) A-I      intronic chr1:224579351(-) A-I      intronic chr1:224579361(-) A-I      intronic chr1:224577924(-) A-I      intronic chr1:224577919(-) A-I      intronic chr1:224577867(-) A-I      intronic chr1:224578025(-) A-I      intronic chr1:224582344(-) A-I      intronic chr1:224582345(-) A-I      intronic chr1:224582403(-) A-I      intronic chr1:224579389(-) A-I      intronic chr1:224582461(-) A-I      intronic chr1:224614736(-) A-I      intronic chr1:224614729(-) A-I      intronic chr1:224614677(-) A-I      intronic chr1:224613832(-) A-I      intronic chr1:224613763(-) A-I      intronic chr1:224613756(-) A-I      intronic chr1:224613698(-) A-I      intronic chr1:224609402(-) A-I      intronic chr1:224603338(-) A-I      intronic chr1:224579398(-) A-I      intronic chr1:224603248(-) A-I      intronic chr1:224603193(-) A-I      intronic chr1:224602619(-) A-I      intronic chr1:224602438(-) A-I      intronic chr1:224602437(-) A-I      intronic chr1:224601978(-) A-I      intronic chr1:224601977(-) A-I      intronic chr1:224601976(-) A-I      intronic chr1:224601940(-) A-I      intronic chr1:224601763(-) A-I      intronic chr1:224601754(-) A-I      intronic chr1:224601751(-) A-I      intronic chr1:224601717(-) A-I      intronic chr1:224601614(-) A-I      intronic chr1:224599690(-) A-I      intronic chr1:224582303(-) A-I      intronic chr1:224599572(-) A-I      intronic chr1:224598666(-) A-I      intronic chr1:224598519(-) A-I      intronic chr1:224598515(-) A-I      intronic chr1:224595438(-) A-I      intronic chr1:224582313(-) A-I      intronic chr1:224595429(-) A-I      intronic chr1:224595424(-) A-I      intronic chr1:224595413(-) A-I      intronic chr1:224595349(-) A-I      intronic chr1:224594737(-) A-I      intronic chr1:224591633(-) A-I      intronic chr1:224616842(-) A-I      intronic chr1:224599500(-) A-I      intronic chr1:224588315(-) A-I      intronic chr1:224584469(-) A-I      intronic chr1:224591027(-) A-I      intronic chr1:224579301(-) A-I      intronic chr1:224587627(-) A-I      intronic chr1:224609381(-) A-I      intronic chr1:224584583(-) A-I      intronic chr1:224603366(-) A-I      intronic chr1:224577978(-) A-I      intronic chr1:224588494(-) A-I      intronic chr1:224578902(-) A-I      intronic chr1:224605371(-) A-I      intronic chr1:224598479(-) A-I      intronic chr1:224579326(-) A-I      intronic chr1:224605258(-) A-I      intronic chr1:224604108(-) A-I      intronic chr1:224578016(-) A-I      intronic chr1:224582384(-) A-I      intronic chr1:224590973(-) A-I      intronic chr1:224580027(-) A-I      intronic chr1:224582387(-) A-I      intronic chr1:224599486(-) A-I      intronic chr1:224587552(-) A-I      intronic chr1:224591395(-) A-I      intronic chr1:224595276(-) A-I      intronic chr1:224590915(-) A-I      intronic chr1:224614542(-) A-I      intronic chr1:224599532(-) A-I      intronic chr1:224584911(-) A-I      intronic chr1:224578088(-) A-I      intronic chr1:224580044(-) A-I      intronic chr1:224577915(-) A-I      intronic chr1:224595339(-) A-I      intronic chr1:224588521(-) A-I      intronic chr1:224578094(-) A-I      intronic chr1:224578946(-) A-I      intronic chr1:224602478(-) A-I      intronic chr1:224577864(-) A-I      intronic chr1:224598565(-) A-I      intronic chr1:224579821(-) A-I      intronic chr1:224579321(-) A-I      intronic chr1:224613633(-) A-I      intronic chr1:224594606(-) A-I      intronic chr1:224606996(-) A-I      intronic chr1:224599536(-) A-I      intronic chr1:224598446(-) A-I      intronic chr1:224601666(-) A-I      intronic chr1:224587643(-) A-I      intronic chr1:224613628(-) A-I      intronic chr1:224584473(-) A-I      intronic chr1:224584888(-) A-I      intronic chr1:224579271(-) A-I      intronic chr1:224580000(-) A-I      intronic chr1:224584404(-) A-I      intronic chr1:224602682(-) A-I      intronic chr1:224595483(-) A-I      intronic chr1:224590870(-) A-I      intronic chr1:224603435(-) A-I      intronic chr1:224605159(-) A-I      intronic chr1:224584981(-) A-I      intronic chr1:224614764(-) A-I      intronic chr1:224577907(-) A-I      intronic chr1:224578906(-) A-I      intronic chr1:224584541(-) A-I      intronic chr1:224609440(-) A-I      intronic chr1:224595253(-) A-I      intronic chr1:224587591(-) A-I      intronic chr1:224582304(-) A-I      intronic chr1:224591063(-) A-I      intronic chr1:224579340(-) A-I      intronic chr1:224579026(-) A-I      intronic chr1:224601860(-) A-I      intronic chr1:224591024(-) A-I      intronic chr1:224599652(-) A-I      intronic chr1:224590918(-) A-I      intronic chr1:224578097(-) A-I      intronic chr1:224595375(-) A-I      intronic chr1:224582469(-) A-I      intronic chr1:224587605(-) A-I      intronic chr1:224584564(-) A-I      intronic chr1:224598498(-) A-I      intronic chr1:224591382(-) A-I      intronic chr1:224602431(-) A-I      intronic chr1:224595362(-) A-I      intronic chr1:224584960(-) A-I      intronic chr1:224605218(-) A-I      intronic chr1:224605163(-) A-I      intronic chr1:224597457(-) A-I      intronic chr1:224590948(-) A-I      intronic chr1:224588543(-) A-I      intronic chr1:224579305(-) A-I      intronic chr1:224587590(-) A-I      intronic chr1:224613688(-) A-I      intronic chr1:224601945(-) A-I      intronic chr1:224578425(-) A-I      intronic chr1:224598554(-) A-I      intronic chr1:224598549(-) A-I      intronic chr1:224605150(-) A-I      intronic chr1:224578956(-) A-I      intronic chr1:224578920(-) A-I      intronic chr1:224587638(-) A-I      intronic chr1:224608572(-) A-I      intronic chr1:224605292(-) A-I      intronic chr1:224609192(-) A-I      intronic chr1:224579344(-) A-I      intronic chr1:224599540(-) A-I      intronic chr1:224577986(-) A-I      intronic chr1:224601922(-) A-I      intronic chr1:224613833(-) A-I      intronic chr1:224598640(-) A-I      intronic chr1:224611334(-) A-I      intronic chr1:224598694(-) A-I      intronic chr1:224591613(-) A-I      intronic chr1:224590972(-) A-I      intronic chr1:224605251(-) A-I      intronic chr1:224616852(-) A-I      intronic chr1:224588520(-) A-I      intronic chr1:224584896(-) A-I      intronic chr1:224603443(-) A-I      intronic chr1:224591442(-) A-I      intronic chr1:224578095(-) A-I      intronic chr1:224595484(-) A-I      intronic chr1:224598503(-) A-I      intronic chr1:224591468(-) A-I      intronic chr1:224577960(-) A-I      intronic chr1:224597395(-) A-I      intronic chr1:224579261(-) A-I      intronic chr1:224604107(-) A-I      intronic chr1:224584495(-) A-I      intronic chr1:224604062(-) A-I      intronic chr1:224602688(-) A-I      intronic chr1:224603291(-) A-I      intronic chr1:224591473(-) A-I      intronic chr1:224591388(-) A-I      intronic chr1:224578470(-) A-I      intronic chr1:224608573(-) A-I      intronic chr1:224594589(-) A-I      intronic chr1:224590883(-) A-I      intronic chr1:224579018(-) A-I      intronic chr1:224578118(-) A-I      intronic chr1:224579312(-) A-I      intronic chr1:224605296(-) A-I      intronic chr1:224578049(-) A-I      intronic chr1:224591019(-) A-I      intronic chr1:224584972(-) A-I      intronic chr1:224599627(-) A-I      intronic chr1:224578015(-) A-I      intronic chr1:224590947(-) A-I      intronic chr1:224605332(-) A-I      intronic chr1:224577914(-) A-I      intronic chr1:224579366(-) A-I      intronic chr1:224584544(-) A-I      intronic chr1:224591064(-) A-I      intronic chr1:224591592(-) A-I      intronic chr1:224578877(-) A-I      intronic chr1:224590866(-) A-I      intronic chr1:224584943(-) A-I      intronic chr1:224577982(-) A-I      intronic chr1:224590936(-) A-I      intronic chr1:224577946(-) A-I      intronic chr1:224582486(-) A-I      intronic chr1:224579367(-) A-I      intronic chr1:224577870(-) A-I      intronic chr1:224587546(-) A-I      intronic chr1:224603332(-) A-I      intronic chr1:224599528(-) A-I      intronic chr1:224578004(-) A-I      intronic chr1:224588527(-) A-I      intronic chr1:224598593(-) A-I      intronic chr1:224605345(-) A-I      intronic chr1:224598484(-) A-I      intronic chr1:224584558(-) A-I      intronic chr1:224579385(-) A-I      intronic chr1:224579357(-) A-I      intronic chr1:224582483(-) A-I      intronic chr1:224577884(-) A-I      intronic chr1:224590903(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	WDR26	chr1:224579366(-) A-I intron -    21960545   //22327324 chr1:224584888(-) A-I intron -    22327324 chr1:224599486(-) A-I intron -    21960545   //22327324 chr1:224577914(-) A-I intron -    21960545 chr1:224578470(-) A-I intron -    21960545 chr1:224579344(-) A-I intron -    21960545 chr1:224579367(-) A-I intron -    21960545 chr1:224584981(-) A-I intron -    21960545 chr1:224587552(-) A-I intron -    21960545 chr1:224587638(-) A-I intron -    21960545 chr1:224587643(-) A-I intron -    21960545 chr1:224595484(-) A-I intron -    21960545 chr1:224599528(-) A-I intron -    21960545 chr1:224599627(-) A-I intron -    21960545 chr1:224599652(-) A-I intron -    21960545 chr1:224602437(-) A-I intron -    21960545 chr1:224605258(-) A-I intron -    21960545 chr1:224605292(-) A-I intron -    21960545 chr1:224577884(-) A-G intron -    22484847 chr1:224577907(-) A-G intron -    22484847 chr1:224577914(-) A-G intron -    22484847 chr1:224577946(-) A-G intron -    22484847 chr1:224577960(-) A-G intron -    22484847 chr1:224578049(-) A-G intron -    22484847 chr1:224578088(-) A-G intron -    22484847 chr1:224578094(-) A-G intron -    22484847 chr1:224578095(-) A-G intron -    22484847 chr1:224578470(-) A-G intron -    22484847 chr1:224578906(-) A-G intron -    22484847 chr1:224578946(-) A-G intron -    22484847 chr1:224579271(-) A-G intron -    22484847 chr1:224579305(-) A-G intron -    22484847 chr1:224579340(-) A-G intron -    22484847 chr1:224579344(-) A-G intron -    22484847 chr1:224579366(-) A-G intron -    22484847 chr1:224579367(-) A-G intron -    22484847 chr1:224580000(-) A-G intron -    22484847 chr1:224580027(-) A-G intron -    22484847 chr1:224580070(-) C-T intron -    22484847 chr1:224582483(-) A-G intron -    22484847 chr1:224582486(-) A-G intron -    22484847 chr1:224584541(-) A-G intron -    22484847 chr1:224584888(-) A-G intron -    22484847 chr1:224584972(-) A-G intron -    22484847 chr1:224584981(-) A-G intron -    22484847 chr1:224587590(-) A-G intron -    22484847 chr1:224587591(-) A-G intron -    22484847 chr1:224587638(-) A-G intron -    22484847 chr1:224587643(-) A-G intron -    22484847 chr1:224588494(-) A-G intron -    22484847 chr1:224588520(-) A-G intron -    22484847 chr1:224588521(-) A-G intron -    22484847 chr1:224588527(-) A-G intron -    22484847 chr1:224588543(-) A-G intron -    22484847 chr1:224590870(-) A-G intron -    22484847 chr1:224590883(-) A-G intron -    22484847 chr1:224590903(-) A-G intron -    22484847 chr1:224590918(-) A-G intron -    22484847 chr1:224590936(-) A-G intron -    22484847 chr1:224590947(-) A-G intron -    22484847 chr1:224590948(-) A-G intron -    22484847 chr1:224590972(-) A-G intron -    22484847 chr1:224590973(-) A-G intron -    22484847 chr1:224591019(-) A-G intron -    22484847 chr1:224591024(-) A-G intron -    22484847 chr1:224591027(-) A-G intron -    22484847 chr1:224591382(-) A-G intron -    22484847 chr1:224591388(-) A-G intron -    22484847 chr1:224595253(-) A-G intron -    22484847 chr1:224595339(-) A-G intron -    22484847 chr1:224595362(-) A-G intron -    22484847 chr1:224595484(-) A-G intron -    22484847 chr1:224598498(-) A-G intron -    22484847 chr1:224598640(-) A-G intron -    22484847 chr1:224599486(-) A-G intron -    22484847 chr1:224599627(-) A-G intron -    22484847 chr1:224600828(-) A-G intron -    22484847 chr1:224600887(-) A-G intron -    22484847 chr1:224601666(-) A-G intron -    22484847 chr1:224601703(-) T-C intron -    22484847 chr1:224601922(-) A-G intron -    22484847 chr1:224601945(-) A-G intron -    22484847 chr1:224602431(-) A-G intron -    22484847 chr1:224604062(-) A-G intron -    22484847 chr1:224604107(-) A-G intron -    22484847 chr1:224604108(-) A-G intron -    22484847 chr1:224605163(-) A-G intron -    22484847 chr1:224605258(-) A-G intron -    22484847 chr1:224605292(-) A-G intron -    22484847 chr1:224609192(-) A-G intron -    22484847 chr1:224609197(-) G-A intron -    22484847 chr1:224609381(-) A-G intron -    22484847 chr1:224614699(-) C-T intron -    22484847 chr1:224614764(-) A-G intron -    22484847 chr1:224614807(-) T-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	WDR26	chr1:224573225-224573226(-) m6A 3'UTR       24981863//22608085 chr1:224573273-224573274(-) m6A 3'UTR       24981863//22608085 chr1:224573332-224573333(-) m6A 3'UTR       24981863//22608085 chr1:224573358-224573359(-) m6A 3'UTR       22608085 chr1:224574665-224574666(-) m6A 3'UTR//intron       27773535 chr1:224575813-224575814(-) m6A 3'UTR//intron       24981863//28052920 chr1:224575927-224575928(-) m6A 3'UTR//intron       24981863 chr1:224576633-224576634(-) m6A 3'UTR//intron       26404942 chr1:224576699-224576700(-) m6A 3'UTR//intron       26404942 chr1:224576714-224576715(-) m6A 3'UTR//intron       26404942 chr1:224576726-224576727(-) m6A 3'UTR//intron       26404942 chr1:224577160-224577161(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr1:224577258-224577259(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:224577287-224577288(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:224577324-224577325(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:224577386-224577387(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:224577414-224577415(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:224577440-224577441(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:224577461-224577462(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr1:224581546-224581547(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr1:224581563-224581564(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr1:224581624-224581625(-) m6A 3'UTR//CDS       27773535//22575960 chr1:224581639-224581640(-) m6A 3'UTR//CDS       27773535//22575960 chr1:224581680-224581681(-) m6A 3'UTR//CDS       27773535 chr1:224586593-224586594(-) m6A 3'UTR//CDS//exon       27773535 chr1:224586602-224586603(-) Cm 3'UTR//CDS//exon       - chr1:224586608-224586609(-) m6A 3'UTR//CDS//exon       27773535 chr1:224586660-224586661(-) m6A 3'UTR//CDS//exon       27773535 chr1:224588703-224588704(-) Cm 3'UTR//CDS//exon       - chr1:224588730-224588731(-) m6A 3'UTR//CDS       22575960 chr1:224599179-224599180(-) m6A 3'UTR//CDS       27773535 chr1:224600685-224600686(-) m6A exon//intron       27773535 chr1:224606042-224606043(-) Gm 3'UTR//CDS//exon       - chr1:224619478-224619479(-) m6A 5'UTR//CDS//exon//intron       - chr1:224621411-224621412(-) m6A CDS//exon//intron       - chr1:224621480-224621481(-) m6A CDS//exon//intron       24284625//24981863//28052920//22608085 chr1:224621652-224621653(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22608085 chr1:224621714-224621715(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr1:224621726-224621727(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr1:224621888-224621889(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548am-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Urine     -
	WDR26	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548am-5p
Interactor2: WDR26

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.