Basic Information:

  VIRBase ID:  

HHID00109172

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548am-5p:  MIMAT0022740          TRIM2:  NM_001375523     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548am-5p	TRIM2
miRBase Accession/Entrez ID	MIMAT0022740	23321
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CMT2R//RNF86

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548am-5p	rs1023899452 chrX:16627065    G/T rs1319380894 chrX:16627063    C/G rs181147953 chrX:16627076    T/G rs768483765 chrX:16627055    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TRIM2	chr4:154230840(+) A-I      ncRNA chr4:154230829(+) A-I      ncRNA chr4:154230845(+) A-I      ncRNA chr4:154227167(+) A-I      intronic chr4:154222417(+) A-I      intronic chr4:154243424(+) A-I      intronic chr4:154222200(+) A-I      intronic chr4:154208315(+) A-I      intronic chr4:154225289(+) A-I      intronic chr4:154203625(+) A-I      intronic chr4:154222196(+) A-I      intronic chr4:154211834(+) A-I      intronic chr4:154211822(+) A-I      intronic chr4:154227231(+) A-I      intronic chr4:154234854(+) A-I      intronic chr4:154243398(+) A-I      intronic chr4:154243399(+) A-I      intronic chr4:154243416(+) A-I      intronic chr4:154255656(+) A-I      intronic chr4:154222416(+) A-I      intronic chr4:154161160(+) A-I      intronic chr4:154203838(+) A-I      intronic chr4:154151433(+) A-I      intronic chr4:154203837(+) A-I      intronic chr4:154199800(+) A-I      intronic chr4:154199780(+) A-I      intronic chr4:154227230(+) A-I      intronic chr4:154227213(+) A-I      intronic chr4:154199741(+) A-I      intronic chr4:154203820(+) A-I      intronic chr4:154199440(+) A-I      intronic chr4:154199369(+) A-I      intronic chr4:154169362(+) A-I      intronic chr4:154169337(+) A-I      intronic chr4:154169329(+) A-I      intronic chr4:154168603(+) A-I      intronic chr4:154167083(+) A-I      intronic chr4:154203819(+) A-I      intronic chr4:154199831(+) A-I      intronic chr4:154203804(+) A-I      intronic chr4:154243448(+) A-I      intronic chr4:154160482(+) A-I      intronic chr4:154168613(+) A-I      intronic chr4:154168550(+) A-I      intronic chr4:154161268(+) A-I      intronic chr4:154161266(+) A-I      intronic chr4:154160389(+) A-I      intronic chr4:154161248(+) A-I      intronic chr4:154161169(+) A-I      intronic chr4:154161166(+) A-I      intronic chr4:154158712(+) A-I      intronic chr4:154161151(+) A-I      intronic chr4:154161147(+) A-I      intronic chr4:154142460(+) A-I      intronic chr4:154085391(+) A-I      intronic chr4:154085394(+) A-I      intronic chr4:154087729(+) A-I      intronic chr4:154087737(+) A-I      intronic chr4:154093414(+) A-I      intronic chr4:154098552(+) A-I      intronic chr4:154098553(+) A-I      intronic chr4:154111938(+) A-I      intronic chr4:154112098(+) A-I      intronic chr4:154129185(+) A-I      intronic chr4:154129233(+) A-I      intronic chr4:154133809(+) A-I      intronic chr4:154133816(+) A-I      intronic chr4:154142466(+) A-I      intronic chr4:154142482(+) A-I      intronic chr4:154151432(+) A-I      intronic chr4:154151445(+) A-I      intronic chr4:154151523(+) A-I      intronic chr4:154153571(+) A-I      intronic chr4:154153592(+) A-I      intronic chr4:154222435(+) A-I      intronic chr4:154199695(+) A-I      intronic chr4:154199804(+) A-I      intronic chr4:154117236(+) A-I      intronic chr4:154199925(+) A-I      intronic chr4:154094954(+) A-I      intronic chr4:154129343(+) A-I      intronic chr4:154238680(+) A-I      intronic chr4:154200837(+) A-I      intronic chr4:154128159(+) A-I      intronic chr4:154128167(+) A-I      intronic chr4:154209538(+) A-I      intronic chr4:154169287(+) A-I      intronic chr4:154199812(+) A-I      intronic chr4:154097546(+) A-I      intronic chr4:154204053(+) A-I      intronic chr4:154201617(+) A-I      intronic chr4:154120987(+) A-I      intronic chr4:154208367(+) A-I      intronic chr4:154158009(+) A-I      intronic chr4:154100142(+) A-I      intronic chr4:154158666(+) A-I      intronic chr4:154113539(+) A-I      intronic chr4:154209539(+) A-I      intronic chr4:154172986(+) A-I      intronic chr4:154222184(+) A-I      intronic chr4:154199722(+) A-I      intronic chr4:154165613(+) A-I      intronic chr4:154209413(+) A-I      intronic chr4:154201676(+) A-I      intronic chr4:154221421(+) A-I      intronic chr4:154099066(+) A-I      intronic chr4:154158068(+) A-I      intronic chr4:154199431(+) A-I      intronic chr4:154255642(+) A-I      intronic chr4:154201105(+) A-I      intronic chr4:154128181(+) A-I      intronic chr4:154201799(+) A-I      intronic chr4:154132855(+) A-I      intronic chr4:154209333(+) A-I      intronic chr4:154255754(+) A-I      intronic chr4:154186548(+) A-I      intronic chr4:154161116(+) A-I      intronic chr4:154201914(+) A-I      intronic chr4:154201654(+) A-I      intronic chr4:154153504(+) A-I      intronic chr4:154203655(+) A-I      intronic chr4:154199455(+) A-I      intronic chr4:154158782(+) A-I      intronic chr4:154199793(+) A-I      intronic chr4:154113698(+) A-I      intronic chr4:154221918(+) A-I      intronic chr4:154202043(+) A-I      intronic chr4:154092460(+) A-I      intronic chr4:154255662(+) A-I      intronic chr4:154199463(+) A-I      intronic chr4:154221860(+) A-I      intronic chr4:154199723(+) A-I      intronic chr4:154201766(+) A-I      intronic chr4:154097484(+) A-I      intronic chr4:154150516(+) A-I      intronic chr4:154241865(+) A-I      intronic chr4:154117367(+) A-I      intronic chr4:154222371(+) A-I      intronic chr4:154084536(+) A-I      intronic chr4:154224472(+) A-I      intronic chr4:154092483(+) A-I      intronic chr4:154124697(+) A-I      intronic chr4:154097463(+) A-I      intronic chr4:154158016(+) A-I      intronic chr4:154199786(+) A-I      intronic chr4:154158767(+) A-I      intronic chr4:154209468(+) A-I      intronic chr4:154243488(+) A-I      intronic chr4:154222152(+) A-I      intronic chr4:154225501(+) A-I      intronic chr4:154156514(+) A-I      intronic chr4:154157908(+) A-I      intronic chr4:154153500(+) A-I      intronic chr4:154156635(+) A-I      intronic chr4:154120975(+) A-I      intronic chr4:154153410(+) A-I      intronic chr4:154098985(+) A-I      intronic chr4:154160479(+) A-I      intronic chr4:154184219(+) A-I      intronic chr4:154234833(+) A-I      intronic chr4:154168572(+) A-I      intronic chr4:154186686(+) A-I      intronic chr4:154096295(+) A-I      intronic chr4:154227140(+) A-I      intronic chr4:154208319(+) A-I      intronic chr4:154206710(+) A-I      intronic chr4:154234918(+) A-I      intronic chr4:154204034(+) A-I      intronic chr4:154187911(+) A-I      intronic chr4:154227137(+) A-I      intronic chr4:154234969(+) A-I      intronic chr4:154243508(+) A-I      intronic chr4:154168618(+) A-I      intronic chr4:154241885(+) A-I      intronic chr4:154097441(+) A-I      intronic chr4:154199528(+) A-I      intronic chr4:154199405(+) A-I      intronic chr4:154165110(+) A-I      intronic chr4:154201209(+) A-I      intronic chr4:154168736(+) A-I      intronic chr4:154209442(+) A-I      intronic chr4:154201168(+) A-I      intronic chr4:154227166(+) A-I      intronic chr4:154221937(+) A-I      intronic chr4:154168642(+) A-I      intronic chr4:154116593(+) A-I      intronic chr4:154161104(+) A-I      intronic chr4:154186545(+) A-I      intronic chr4:154160508(+) A-I      intronic chr4:154224505(+) A-I      intronic chr4:154168612(+) A-I      intronic chr4:154099093(+) A-I      intronic chr4:154186515(+) A-I      intronic chr4:154204170(+) A-I      intronic chr4:154200833(+) A-I      intronic chr4:154092482(+) A-I      intronic chr4:154200984(+) A-I      intronic chr4:154199527(+) A-I      intronic chr4:154211818(+) A-I      intronic chr4:154133704(+) A-I      intronic chr4:154158807(+) A-I      intronic chr4:154222232(+) A-I      intronic chr4:154199767(+) A-I      intronic chr4:154084477(+) A-I      intronic chr4:154153486(+) A-I      intronic chr4:154199857(+) A-I      intronic chr4:154129429(+) A-I      intronic chr4:154208200(+) A-I      intronic chr4:154081805(+) A-I      intronic chr4:154168641(+) A-I      intronic chr4:154158649(+) A-I      intronic chr4:154169248(+) A-I      intronic chr4:154201146(+) A-I      intronic chr4:154208184(+) A-I      intronic chr4:154094667(+) A-I      intronic chr4:154094634(+) A-I      intronic chr4:154204134(+) A-I      intronic chr4:154208230(+) A-I      intronic chr4:154204162(+) A-I      intronic chr4:154081806(+) A-I      intronic chr4:154158685(+) A-I      intronic chr4:154158045(+) A-I      intronic chr4:154231000(+) A-I      ncRNA

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TRIM2	chr4:154112086(+) A-G intron -    22484847 chr4:154158666(+) A-G intron -    22484847 chr4:154169400(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TRIM2	chr4:154197055-154197056(+) m6A 5'UTR//CDS//exon       24284625 chr4:154197105-154197106(+) m6A 5'UTR//CDS//exon       24284625 chr4:154197145-154197146(+) m6A 5'UTR//CDS//exon       24284625 chr4:154197163-154197164(+) m6A 5'UTR//CDS//exon       24284625 chr4:154216560-154216561(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr4:154216621-154216622(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr4:154216671-154216672(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154216740-154216741(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154216770-154216771(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154216813-154216814(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154216836-154216837(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154216862-154216863(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154216906-154216907(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154216957-154216958(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154216976-154216977(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154217117-154217118(+) m6A CDS       24284625//24209618//24981863//22608085 chr4:154256074-154256075(+) m6A CDS       24284625//24209618//25456834//22608085 chr4:154256161-154256162(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154256186-154256187(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr4:154256232-154256233(+) m6A 3'UTR       24209618//25456834//24981863//22608085 chr4:154256317-154256318(+) m6A 3'UTR       24209618//24981863//22608085 chr4:154256340-154256341(+) m6A 3'UTR       24209618//24981863//22608085 chr4:154256361-154256362(+) m6A 3'UTR       22608085 chr4:154256376-154256377(+) m6A 3'UTR       22608085 chr4:154256395-154256396(+) m6A 3'UTR       22608085 chr4:154256413-154256414(+) m6A 3'UTR       22608085 chr4:154256428-154256429(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548am-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Urine     -
	TRIM2	Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548am-5p
Interactor2: TRIM2

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.