Basic Information:

  VIRBase ID:  

HHID00109152

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548am-5p:  MIMAT0022740          SRP9:  NM_003133     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548am-5p	SRP9
miRBase Accession/Entrez ID	MIMAT0022740	6726
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ALURBP

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548am-5p	rs1023899452 chrX:16627065    G/T rs1319380894 chrX:16627063    C/G rs181147953 chrX:16627076    T/G rs768483765 chrX:16627055    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SRP9	chr1:225975151(+) A-I      intronic chr1:225975168(+) A-I      intronic chr1:225975177(+) A-I      intronic chr1:225974733(+) A-I      intronic chr1:225974612(+) A-I      NonSyn:Ile->Val chr1:225974768(+) A-I      intronic chr1:225975081(+) A-I      intronic chr1:225974562(+) A-I      intronic chr1:225974755(+) A-I      intronic chr1:225973568(+) A-I      intronic chr1:225973510(+) A-I      intronic chr1:225973485(+) A-I      intronic chr1:225973441(+) A-I      intronic chr1:225973281(+) A-I      intronic chr1:225973222(+) A-I      intronic chr1:225975088(+) A-I      intronic chr1:225972356(+) A-I      intronic chr1:225973212(+) A-I      intronic chr1:225972004(+) A-I      intronic chr1:225972437(+) A-I      intronic chr1:225972053(+) A-I      intronic chr1:225972397(+) A-I      intronic chr1:225972401(+) A-I      intronic chr1:225972532(+) A-I      intronic chr1:225972153(+) A-I      intronic chr1:225972214(+) A-I      intronic chr1:225972066(+) A-I      intronic chr1:225975201(+) A-I      intronic chr1:225975181(+) A-I      intronic chr1:225975141(+) A-I      intronic chr1:225975136(+) A-I      intronic chr1:225972528(+) A-I      intronic chr1:225972509(+) A-I      intronic chr1:225972394(+) A-I      intronic chr1:225975126(+) A-I      intronic chr1:225972405(+) A-I      intronic chr1:225972078(+) A-I      intronic chr1:225972539(+) A-I      intronic chr1:225972029(+) A-I      intronic chr1:225975119(+) A-I      intronic chr1:225972417(+) A-I      intronic chr1:225972423(+) A-I      intronic chr1:225972366(+) A-I      intronic chr1:225972504(+) A-I      intronic chr1:225972090(+) A-I      intronic chr1:225974679(+) A-I      3'UTR chr1:225972489(+) A-I      intronic chr1:225972371(+) A-I      intronic chr1:225972433(+) A-I      intronic chr1:225974811(+) A-I      intronic chr1:225972094(+) A-I      intronic chr1:225974761(+) A-I      intronic chr1:225972048(+) A-I      intronic chr1:225975057(+) A-I      intronic chr1:225975034(+) A-I      intronic chr1:225974731(+) A-I      intronic chr1:225974717(+) A-I      intronic chr1:225975025(+) A-I      intronic chr1:225974711(+) A-I      intronic chr1:225975017(+) A-I      intronic chr1:225974981(+) A-I      intronic chr1:225974710(+) A-I      intronic chr1:225972327(+) A-I      intronic chr1:225972981(+) A-I      intronic chr1:225975115(+) A-I      intronic chr1:225975053(+) A-I      intronic chr1:225972319(+) A-I      intronic chr1:225974674(+) A-I      3'UTR chr1:225972088(+) A-I      intronic chr1:225973511(+) A-I      intronic chr1:225972365(+) A-I      intronic chr1:225972194(+) A-I      intronic chr1:225973565(+) A-I      intronic chr1:225975051(+) A-I      intronic chr1:225975049(+) A-I      intronic chr1:225974568(+) A-I      NonSyn:Gln->Arg chr1:225974581(+) A-I      Syn:Leu->Leu chr1:225974662(+) A-I      Syn:Ser->Ser chr1:225974645(+) A-I      NonSyn:Ser->Gly chr1:225974600(+) A-I      NonSyn:Ser->Gly chr1:225974619(+) A-I      NonSyn:His->Arg chr1:225974614(+) A-I      NonSyn:Ile->Met chr1:225974644(+) A-I      Syn:Ser->Ser chr1:225972531(+) A-I      intronic chr1:225975110(+) A-I      intronic chr1:225972311(+) A-I      intronic chr1:225974746(+) A-I      intronic chr1:225975132(+) A-I      intronic chr1:225972464(+) A-I      intronic chr1:225974677(+) A-I      3'UTR chr1:225975058(+) A-I      intronic chr1:225974684(+) A-I      3'UTR chr1:225975186(+) A-I      intronic chr1:225972326(+) A-I      intronic chr1:225975039(+) A-I      intronic chr1:225974672(+) A-I      3'UTR chr1:225975185(+) A-I      intronic chr1:225972312(+) A-I      intronic chr1:225975109(+) A-I      intronic chr1:225972463(+) A-I      intronic chr1:225973559(+) A-I      intronic chr1:225974982(+) A-I      intronic chr1:225975178(+) A-I      intronic chr1:225974748(+) A-I      intronic chr1:225972358(+) A-I      intronic chr1:225974718(+) A-I      intronic chr1:225974735(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SRP9	chr1:225975474(+) A-I intron -    15342557 chr1:225975921(+) A-I intron -    15258596 chr1:225975932(+) A-I intron -    15258596 chr1:225975936(+) A-I intron -    15258596 chr1:225975941(+) A-I intron -    15258596 chr1:225975945(+) A-I intron -    15258596 chr1:225975954(+) A-I intron -    15258596   //21960545   //22327324 chr1:225976243(+) A-I intron -    15342557 chr1:225976244(+) A-I intron -    15342557 chr1:225976265(+) A-I intron -    15342557 chr1:225976283(+) A-I intron -    15342557 chr1:225974581(+) A-I exon CDS    22327324 chr1:225974735(+) A-I intron -    21960545   //22327324 chr1:225974746(+) A-I intron -    21960545   //22327324 chr1:225974748(+) A-I intron -    21960545   //22327324 chr1:225975110(+) A-I intron -    22327324 chr1:225975115(+) A-I intron -    22327324 chr1:225975178(+) A-I intron -    22327324 chr1:225976060(+) A-I intron -    21960545   //22327324 chr1:225976193(+) A-I intron -    21960545   //22327324 chr1:225976320(+) A-I intron -    22327324 chr1:225974614(+) A-I exon CDS    21960545 chr1:225975946(+) A-I intron -    21960545 chr1:225975947(+) A-I intron -    21960545 chr1:225975950(+) A-I intron -    21960545 chr1:225975990(+) A-I intron -    21960545 chr1:225976051(+) A-I intron -    21960545 chr1:225976198(+) A-I intron -    21960545 chr1:225974674(+) A-I exon 3'UTR    21960545 chr1:225974717(+) A-I intron -    21960545 chr1:225975913(+) A-I intron -    21960545 chr1:225975976(+) A-I intron -    21960545 chr1:225976010(+) A-I intron -    21960545 chr1:225974614(+) A-G exon CDS    21725310 chr1:225976243(+) A-G intron -    21725310 chr1:225976582(+) A-G intron -    21725310

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SRP9	chr1:225965550-225965551(+) m6A 5'UTR       24981863 chr1:225974331-225974332(+) Tm intron       - chr1:225977644-225977645(+) m6A 3'UTR       27773535 chr1:225977957-225977958(+) m6A 3'UTR       27773535 chr1:225978079-225978080(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548am-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Urine     -
	SRP9	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548am-5p
Interactor2: SRP9

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.