Basic Information:

  VIRBase ID:  

HHID00109142

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548am-5p:  MIMAT0022740          AFDN:  NM_001366320     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548am-5p	AFDN
miRBase Accession/Entrez ID	MIMAT0022740	4301
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	AF6//l-afadin//MLL-AF6//MLLT4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548am-5p	rs1023899452 chrX:16627065    G/T rs1319380894 chrX:16627063    C/G rs181147953 chrX:16627076    T/G rs768483765 chrX:16627055    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	AFDN	chr6:168292335(+) A-I      intronic chr6:168266182(+) A-I      intronic chr6:168266146(+) A-I      intronic chr6:168266073(+) A-I      intronic chr6:168266056(+) A-I      intronic chr6:168305158(+) A-I      intronic chr6:168268296(+) A-I      intronic chr6:168330865(+) A-I      intronic chr6:168330864(+) A-I      intronic chr6:168330655(+) A-I      intronic chr6:168330651(+) A-I      intronic chr6:168283144(+) A-I      intronic chr6:168268970(+) A-I      intronic chr6:168268968(+) A-I      intronic chr6:168266213(+) A-I      intronic chr6:168338137(+) A-I      intronic chr6:168287530(+) A-I      intronic chr6:168306638(+) A-I      intronic chr6:168304988(+) A-I      intronic chr6:168269730(+) A-I      intronic chr6:168356688(+) A-I      intronic chr6:168245811(+) A-I      intronic chr6:168356617(+) A-I      intronic chr6:168269543(+) A-I      intronic chr6:168251757(+) A-I      intronic chr6:168266127(+) A-I      intronic chr6:168306624(+) A-I      intronic chr6:168266106(+) A-I      intronic chr6:168268153(+) A-I      intronic chr6:168274825(+) A-I      intronic chr6:168245816(+) A-I      intronic chr6:168268957(+) A-I      intronic chr6:168268249(+) A-I      intronic chr6:168268964(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548am-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Urine     -
	AFDN	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)|K562 cells     - Membrane HCC cell line (HepG2)     - Nucleolus HCC cell line (HepG2)|K562 cells     - Nucleoplasm K562 cells     - Nucleus Colon cancer cells     24393600 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548am-5p
Interactor2: AFDN

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.