Detail Information

Basic Information:


  VIRBase ID:  

HHID00109015

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548ah-3p:           SPICE1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548ah-3p SPICE1
miRBase
Accession/Entrez ID		 MIMAT0020957 152185
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CCDC52//SPICE

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548ah-3p
rs1036377818 chr4:76575612    C/T
rs1486932451 chr4:76575608    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SPICE1
chr3:113231332(-) A-I      intronic
chr3:113231295(-) A-I      intronic
chr3:113213385(-) A-I      intronic
chr3:113213372(-) A-I      intronic
chr3:113213327(-) A-I      intronic
chr3:113185868(-) A-I      intronic
chr3:113231393(-) A-I      intronic
chr3:113209321(-) A-I      intronic
chr3:113186312(-) A-I      intronic
chr3:113186310(-) A-I      intronic
chr3:113186307(-) A-I      intronic
chr3:113186295(-) A-I      intronic
chr3:113185273(-) A-I      intronic
chr3:113171685(-) A-I      intronic
chr3:113169543(-) A-I      intronic
chr3:113186276(-) A-I      intronic
chr3:113183158(-) A-I      intronic
chr3:113185897(-) A-I      intronic
chr3:113213250(-) A-I      intronic
chr3:113183732(-) A-I      intronic
chr3:113186303(-) A-I      intronic
chr3:113232244(-) A-I      intronic
chr3:113183346(-) A-I      intronic
chr3:113231323(-) A-I      intronic
chr3:113232088(-) A-I      intronic
chr3:113232252(-) A-I      intronic
chr3:113232126(-) A-I      intronic
chr3:113232082(-) A-I      intronic
chr3:113186335(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SPICE1
chr3:113216861(-) A-I intron -    15258596
chr3:113216888(-) A-I intron -    15258596
chr3:113216927(-) A-I intron -    15258596
chr3:113216965(-) A-I intron -    15258596
chr3:113163240(-) T-C exon 3'UTR    22484847
chr3:113163345(-) G-T exon 3'UTR    22484847
chr3:113183158(-) A-G intron -    22484847
chr3:113185313(-) A-G intron -    22484847
chr3:113185897(-) A-G intron -    22484847
chr3:113186303(-) A-G intron -    22484847
chr3:113186333(-) A-G intron -    22484847
chr3:113186335(-) A-G intron -    22484847
chr3:113186368(-) A-G intron -    22484847
chr3:113213250(-) A-G intron -    22484847
chr3:113216674(-) A-G intron -    22484847
chr3:113216880(-) A-G intron -    22484847
chr3:113216911(-) A-G intron -    22484847
chr3:113216927(-) A-G intron -    22484847
chr3:113232082(-) A-G intron -    22484847
chr3:113232088(-) A-G intron -    22484847
chr3:113232244(-) A-G intron -    22484847
chr3:113232252(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SPICE1
chr3:113169273-113169274(-) m6A CDS//exon//intron       27773535
chr3:113172343-113172344(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr3:113172357-113172358(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr3:113172454-113172455(-) m6A CDS//exon//intron       24284625//24981863//27773535//27371828//22608085
chr3:113172482-113172483(-) m6A CDS//exon//intron       24284625//24981863//27773535//27371828//22608085
chr3:113172605-113172606(-) m6A CDS//exon//intron       24284625//24981863//27773535//27371828//22608085
chr3:113172610-113172611(-) m6A CDS//exon//intron       24284625//24981863//27773535//27371828//22608085
chr3:113172688-113172689(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085
chr3:113172707-113172708(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085
chr3:113172726-113172727(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr3:113172776-113172777(-) m6A CDS//exon//intron       27773535//22608085
chr3:113172785-113172786(-) m6A CDS//exon//intron       27773535//22608085
chr3:113218326-113218327(-) m6A CDS//exon       27773535
chr3:113218333-113218334(-) m6A CDS//exon       27773535
chr3:113218375-113218376(-) m6A CDS//exon       27773535
chr3:113233361-113233362(-) m6A 5'UTR//intron       27773535
chr3:113233868-113233869(-) m6A 5'UTR//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548ah-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SPICE1
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane K562 cells     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548ah-3p
Interactor2: SPICE1

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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