Basic Information:

  VIRBase ID:  

HHID00108711

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548am-3p:  MIMAT0019076          MAPK8:  NR_136583     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548am-3p	MAPK8
miRBase Accession/Entrez ID	MIMAT0019076	5599
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	JNK//JNK-46//JNK1//JNK1A2//JNK21B1/2//PRKM8//SAPK1//SAPK1c

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548am-3p	rs1337548768 chrX:16627022    A/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAPK8	chr10:49629683(+) A-I      intronic chr10:49630162(+) A-I      intronic chr10:49629767(+) A-I      intronic chr10:49629628(+) A-I      intronic chr10:49611446(+) A-I      intronic chr10:49630240(+) A-I      intronic chr10:49629593(+) A-I      intronic chr10:49629697(+) A-I      intronic chr10:49611315(+) A-I      intronic chr10:49611815(+) A-I      intronic chr10:49611362(+) A-I      intronic chr10:49611381(+) A-I      intronic chr10:49629662(+) A-I      intronic chr10:49629698(+) A-I      intronic chr10:49611370(+) A-I      intronic chr10:49611317(+) A-I      intronic chr10:49629638(+) A-I      intronic chr10:49630227(+) A-I      intronic chr10:49611314(+) A-I      intronic chr10:49629759(+) A-I      intronic chr10:49629601(+) A-I      intronic chr10:49629689(+) A-I      intronic chr10:49629775(+) A-I      intronic chr10:49629835(+) A-I      intronic chr10:49629694(+) A-I      intronic chr10:49611245(+) A-I      intronic chr10:49630155(+) A-I      intronic chr10:49611341(+) A-I      intronic chr10:49630327(+) A-I      intronic chr10:49629633(+) A-I      intronic chr10:49629701(+) A-I      intronic chr10:49630129(+) A-I      intronic chr10:49629592(+) A-I      intronic chr10:49630309(+) A-I      intronic chr10:49630304(+) A-I      intronic chr10:49629728(+) A-I      intronic chr10:49629721(+) A-I      intronic chr10:49630336(+) A-I      intronic chr10:49630297(+) A-I      intronic chr10:49630241(+) A-I      intronic chr10:49630204(+) A-I      intronic chr10:49629786(+) A-I      intronic chr10:49630220(+) A-I      intronic chr10:49638454(+) A-I      intronic chr10:49629834(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MAPK8	chr10:49638454(+) A-I intron -    19478186 chr10:49629633(+) A-I intron -    21960545 chr10:49629698(+) A-I intron -    21960545 chr10:49629834(+) A-G intron -    22484847 chr10:49630327(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAPK8	chr10:49612964-49612965(+) m6A CDS//exon//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548am-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	MAPK8	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548am-3p
Interactor2: MAPK8

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.