Detail Information

Basic Information:


  VIRBase ID:  

HHID00108585

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548h-5p:           SIX4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548h-5p SIX4
miRBase
Accession/Entrez ID		 MIMAT0005928 51804
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AREC3

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548h-5p
rs1423828980 chr14:64095086    C/T
rs144194694 chr14:64095094    G/A
rs377270470 chr14:64095095    C/A
rs377270470 chr14:64095095    C/T
rs573600271 chr14:64095093    C/T
rs1000965353 chr16:11306498    A/G
rs1307745356 chr16:11306500    C/T
rs1353674605 chr16:11306491    G/A
rs1353674605 chr16:11306491    G/T
rs149601213 chr16:11306499    C/T
rs563549339 chr16:11306501    G/A
rs956694910 chr16:11306502    C/T
rs988390663 chr16:11306503    G/A
rs1247348117 chr17:13543606    C/T
rs1307196788 chr17:13543599    CAA/C
rs1341303954 chr17:13543598    A/AAAGTAATAG
rs1348342088 chr17:13543609    G/A
rs9913045 chr17:13543607    G/A
rs1285835311 chr8:27048929    A/G
rs1295636494 chr8:27048928    CA/C
rs1306358433 chr8:27048936    G/A
rs1352583339 chr8:27048937    C/T
rs1354349512 chr8:27048928    C/T
rs1391960313 chr8:27048933    A/C
rs561726723 chr8:27048935    C/T
rs748156409 chr8:27048926    G/A
rs748156409 chr8:27048926    G/T
rs1042357839 chr6:131792184    G/A
rs1225605725 chr6:131792194    T/C
rs1257986495 chr6:131792187    G/A
rs1345907099 chr6:131792186    G/T
rs1466227719 chr6:131792183    C/A
rs1466227719 chr6:131792183    C/T
rs906403807 chr6:131792185    C/A
rs1384709035 chr6:131792178    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SIX4
chr14:61182721(-) A-I      intronic
chr14:61184062(-) A-I      intronic
chr14:61183885(-) A-I      intronic
chr14:61183855(-) A-I      intronic
chr14:61184008(-) A-I      intronic
chr14:61184503(-) A-I      intronic
chr14:61183930(-) A-I      intronic
chr14:61184608(-) A-I      intronic
chr14:61183378(-) A-I      intronic
chr14:61184475(-) A-I      intronic
chr14:61184558(-) A-I      intronic
chr14:61184049(-) A-I      intronic
chr14:61178238(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SIX4
chr14:61184608(-) A-I intron -    21960545
chr14:61178246(-) T-C exon 3'UTR    21725310

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SIX4
chr14:61176289-61176290(-) m6A 3'UTR       27773535
chr14:61176303-61176304(-) m6A 3'UTR       27773535
chr14:61176341-61176342(-) m6A 3'UTR       27773535
chr14:61176417-61176418(-) m6A 3'UTR       27773535
chr14:61176767-61176768(-) m6A 3'UTR       27773535
chr14:61176854-61176855(-) m6A 3'UTR       27773535
chr14:61178663-61178664(-) m6A 3'UTR       27773535
chr14:61178670-61178671(-) m6A 3'UTR       27773535
chr14:61179688-61179689(-) m6A 3'UTR       27773535
chr14:61179753-61179754(-) m6A 3'UTR       27773535//22608085
chr14:61179817-61179818(-) m6A 3'UTR       24981863//27773535//22608085
chr14:61179885-61179886(-) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr14:61179892-61179893(-) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr14:61179949-61179950(-) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr14:61179998-61179999(-) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr14:61180032-61180033(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr14:61180054-61180055(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr14:61180061-61180062(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr14:61180123-61180124(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:61180131-61180132(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:61180159-61180160(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:61180189-61180190(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:61180197-61180198(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:61180248-61180249(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr14:61180340-61180341(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:61180449-61180450(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:61180473-61180474(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:61180569-61180570(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:61180677-61180678(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:61180692-61180693(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:61180766-61180767(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:61180783-61180784(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr14:61186551-61186552(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:61186648-61186649(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr14:61186830-61186831(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:61186851-61186852(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:61186910-61186911(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr14:61187117-61187118(-) m6A CDS//exon       24284625//24209618
chr14:61187755-61187756(-) m6A exon//intron       24284625
chr14:61189942-61189943(-) m6A CDS       24284625//27773536
chr14:61189953-61189954(-) m6A CDS       24284625//27773536
chr14:61189974-61189975(-) m6A CDS       24284625//25456834//27773536
chr14:61190175-61190176(-) m6A CDS       24284625//24981863//27371828//27773536
chr14:61190412-61190413(-) m6A CDS       24981863//27371828//27773536
chr14:61190482-61190483(-) m6A CDS       25456834//24981863//27371828//27773536
chr14:61190525-61190526(-) m6A CDS       25456834//24981863//27371828//27773536
chr14:61190748-61190749(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr14:61190801-61190802(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548h-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
SIX4
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548h-5p
Interactor2: SIX4

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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