Basic Information:

  VIRBase ID:  

HHID00108574

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548h-5p:  MIMAT0005928          MAST3:  NM_001393519     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548h-5p	MAST3
miRBase Accession/Entrez ID	MIMAT0005928	23031
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548h-5p	rs1423828980 chr14:64095086    C/T rs144194694 chr14:64095094    G/A rs377270470 chr14:64095095    C/A rs377270470 chr14:64095095    C/T rs573600271 chr14:64095093    C/T rs1000965353 chr16:11306498    A/G rs1307745356 chr16:11306500    C/T rs1353674605 chr16:11306491    G/A rs1353674605 chr16:11306491    G/T rs149601213 chr16:11306499    C/T rs563549339 chr16:11306501    G/A rs956694910 chr16:11306502    C/T rs988390663 chr16:11306503    G/A rs1247348117 chr17:13543606    C/T rs1307196788 chr17:13543599    CAA/C rs1341303954 chr17:13543598    A/AAAGTAATAG rs1348342088 chr17:13543609    G/A rs9913045 chr17:13543607    G/A rs1285835311 chr8:27048929    A/G rs1295636494 chr8:27048928    CA/C rs1306358433 chr8:27048936    G/A rs1352583339 chr8:27048937    C/T rs1354349512 chr8:27048928    C/T rs1391960313 chr8:27048933    A/C rs561726723 chr8:27048935    C/T rs748156409 chr8:27048926    G/A rs748156409 chr8:27048926    G/T rs1042357839 chr6:131792184    G/A rs1225605725 chr6:131792194    T/C rs1257986495 chr6:131792187    G/A rs1345907099 chr6:131792186    G/T rs1466227719 chr6:131792183    C/A rs1466227719 chr6:131792183    C/T rs906403807 chr6:131792185    C/A rs1384709035 chr6:131792178    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAST3	chr19:18251761(+) A-I      intronic chr19:18251769(+) A-I      intronic chr19:18251813(+) A-I      intronic chr19:18214075(+) A-I      intronic chr19:18251825(+) A-I      intronic chr19:18217136(+) A-I      intronic chr19:18244253(+) A-I      intronic chr19:18244293(+) A-I      intronic chr19:18251824(+) A-I      intronic chr19:18244296(+) A-I      intronic chr19:18214077(+) A-I      intronic chr19:18216997(+) A-I      intronic chr19:18226943(+) A-I      intronic chr19:18244245(+) A-I      intronic chr19:18227644(+) A-I      intronic chr19:18227239(+) A-I      intronic chr19:18227229(+) A-I      intronic chr19:18226978(+) A-I      intronic chr19:18226968(+) A-I      intronic chr19:18219440(+) A-I      intronic chr19:18219363(+) A-I      intronic chr19:18219308(+) A-I      intronic chr19:18218988(+) A-I      intronic chr19:18218924(+) A-I      intronic chr19:18218923(+) A-I      intronic chr19:18218914(+) A-I      intronic chr19:18218862(+) A-I      intronic chr19:18217578(+) A-I      intronic chr19:18217142(+) A-I      intronic chr19:18217027(+) A-I      intronic chr19:18217015(+) A-I      intronic chr19:18217002(+) A-I      intronic chr19:18216998(+) A-I      intronic chr19:18216946(+) A-I      intronic chr19:18216181(+) A-I      intronic chr19:18216109(+) A-I      intronic chr19:18216103(+) A-I      intronic chr19:18215927(+) A-I      intronic chr19:18215916(+) A-I      intronic chr19:18214872(+) A-I      intronic chr19:18214846(+) A-I      intronic chr19:18214750(+) A-I      intronic chr19:18214269(+) A-I      intronic chr19:18214195(+) A-I      intronic chr19:18214109(+) A-I      intronic chr19:18213475(+) A-I      intronic chr19:18213471(+) A-I      intronic chr19:18213263(+) A-I      intronic chr19:18212464(+) A-I      intronic chr19:18211204(+) A-I      intronic chr19:18211183(+) A-I      intronic chr19:18211170(+) A-I      intronic chr19:18211083(+) A-I      intronic chr19:18236508(+) A-I      intronic chr19:18250769(+) A-I      intronic chr19:18217652(+) A-I      intronic chr19:18258850(+) A-I      intronic chr19:18254045(+) A-I      intronic chr19:18254035(+) A-I      intronic chr19:18253861(+) A-I      intronic chr19:18253720(+) A-I      intronic chr19:18253643(+) A-I      intronic chr19:18253367(+) A-I      intronic chr19:18253266(+) A-I      intronic chr19:18253242(+) A-I      intronic chr19:18251787(+) A-I      intronic chr19:18251784(+) A-I      intronic chr19:18251778(+) A-I      intronic chr19:18250766(+) A-I      intronic chr19:18250759(+) A-I      intronic chr19:18250756(+) A-I      intronic chr19:18250710(+) A-I      intronic chr19:18248905(+) A-I      intronic chr19:18248737(+) A-I      intronic chr19:18244966(+) A-I      intronic chr19:18244505(+) A-I      intronic chr19:18244490(+) A-I      intronic chr19:18244489(+) A-I      intronic chr19:18244481(+) A-I      intronic chr19:18238454(+) A-I      intronic chr19:18238182(+) A-I      intronic chr19:18238172(+) A-I      intronic chr19:18238171(+) A-I      intronic chr19:18238148(+) A-I      intronic chr19:18236506(+) A-I      intronic chr19:18236496(+) A-I      intronic chr19:18236430(+) A-I      intronic chr19:18258688(+) A-I      intronic chr19:18243792(+) A-I      intronic chr19:18227043(+) A-I      intronic chr19:18259663(+) A-I      intronic chr19:18219431(+) A-I      intronic chr19:18219413(+) A-I      intronic chr19:18248829(+) A-I      intronic chr19:18231592(+) A-I      intronic chr19:18258175(+) A-I      intronic chr19:18214257(+) A-I      intronic chr19:18251839(+) A-I      intronic chr19:18244544(+) A-I      intronic chr19:18251704(+) A-I      intronic chr19:18236898(+) A-I      intronic chr19:18217744(+) A-I      intronic chr19:18251144(+) A-I      intronic chr19:18251146(+) A-I      intronic chr19:18249385(+) A-I      intronic chr19:18249407(+) A-I      intronic chr19:18250154(+) A-I      intronic chr19:18244464(+) A-I      intronic chr19:18215943(+) A-I      intronic chr19:18227288(+) A-I      intronic chr19:18248931(+) A-I      intronic chr19:18237327(+) A-I      intronic chr19:18237939(+) A-I      intronic chr19:18218009(+) A-I      intronic chr19:18251077(+) A-I      intronic chr19:18217110(+) A-I      intronic chr19:18254131(+) A-I      intronic chr19:18227167(+) A-I      intronic chr19:18254036(+) A-I      intronic chr19:18216473(+) A-I      intronic chr19:18237536(+) A-I      intronic chr19:18216389(+) A-I      intronic chr19:18248833(+) A-I      intronic chr19:18246001(+) A-I      intronic chr19:18238595(+) A-I      intronic chr19:18218982(+) A-I      intronic chr19:18227487(+) A-I      intronic chr19:18216015(+) A-I      intronic chr19:18240506(+) A-I      intronic chr19:18214170(+) A-I      intronic chr19:18261058(+) A-I      3'UTR chr19:18260891(+) A-I      3'UTR chr19:18259100(+) A-I      intronic chr19:18260897(+) A-I      3'UTR chr19:18217246(+) A-I      intronic chr19:18214875(+) A-I      intronic chr19:18214094(+) A-I      intronic chr19:18214226(+) A-I      intronic chr19:18215921(+) A-I      intronic chr19:18227668(+) A-I      intronic chr19:18251133(+) A-I      intronic chr19:18237458(+) A-I      intronic chr19:18227004(+) A-I      intronic chr19:18213645(+) A-I      intronic chr19:18245231(+) A-I      intronic chr19:18226984(+) A-I      intronic chr19:18226990(+) A-I      intronic chr19:18237368(+) A-I      intronic chr19:18254026(+) A-I      intronic chr19:18216276(+) A-I      intronic chr19:18238347(+) A-I      intronic chr19:18218881(+) A-I      intronic chr19:18215967(+) A-I      intronic chr19:18244243(+) A-I      intronic chr19:18253428(+) A-I      intronic chr19:18237313(+) A-I      intronic chr19:18252283(+) A-I      intronic chr19:18214767(+) A-I      intronic chr19:18219367(+) A-I      intronic chr19:18218035(+) A-I      intronic chr19:18227602(+) A-I      intronic chr19:18214766(+) A-I      intronic chr19:18214939(+) A-I      intronic chr19:18227220(+) A-I      intronic chr19:18249265(+) A-I      intronic chr19:18219452(+) A-I      intronic chr19:18219398(+) A-I      intronic chr19:18219400(+) A-I      intronic chr19:18218915(+) A-I      intronic chr19:18217155(+) A-I      intronic chr19:18213052(+) A-I      intronic chr19:18254184(+) A-I      intronic chr19:18214260(+) A-I      intronic chr19:18214227(+) A-I      intronic chr19:18250988(+) A-I      intronic chr19:18219014(+) A-I      intronic chr19:18218038(+) A-I      intronic chr19:18217131(+) A-I      intronic chr19:18227603(+) A-I      intronic chr19:18252263(+) A-I      intronic chr19:18259247(+) A-I      intronic chr19:18227242(+) A-I      intronic chr19:18217657(+) A-I      intronic chr19:18227021(+) A-I      intronic chr19:18248899(+) A-I      intronic chr19:18217229(+) A-I      intronic chr19:18227285(+) A-I      intronic chr19:18254236(+) A-I      intronic chr19:18243851(+) A-I      intronic chr19:18243779(+) A-I      intronic chr19:18214171(+) A-I      intronic chr19:18237396(+) A-I      intronic chr19:18236431(+) A-I      intronic chr19:18217238(+) A-I      intronic chr19:18227608(+) A-I      intronic chr19:18216215(+) A-I      intronic chr19:18213431(+) A-I      intronic chr19:18218917(+) A-I      intronic chr19:18250653(+) A-I      intronic chr19:18248900(+) A-I      intronic chr19:18214947(+) A-I      intronic chr19:18227555(+) A-I      intronic chr19:18214866(+) A-I      intronic chr19:18214200(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MAST3	chr19:18219242(+) A-G intron -    22484847 chr19:18236431(+) A-G intron -    22484847 chr19:18248790(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAST3	chr19:18245440-18245441(+) Am CDS       - chr19:18255389-18255390(+) m6A CDS//exon       24284625 chr19:18257816-18257817(+) m6A CDS       - chr19:18258286-18258287(+) m6A CDS       - chr19:18258324-18258325(+) m6A CDS       24981863 chr19:18260128-18260129(+) m6A CDS       - chr19:18260387-18260388(+) m6A CDS       24284625//25456834//24981863//22575960 chr19:18260531-18260532(+) m6A CDS       24284625//25456834//24981863//22575960 chr19:18260619-18260620(+) m6A 3'UTR       24284625 chr19:18261390-18261391(+) m6A 3'UTR       24284625//24981863 chr19:18261411-18261412(+) m6A 3'UTR       24284625//24981863//22608085 chr19:18261432-18261433(+) m6A 3'UTR       24284625//24981863//22608085 chr19:18262137-18262138(+) m6A 3'UTR       24981863 chr19:18262223-18262224(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548h-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	MAST3	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548h-5p
Interactor2: MAST3

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.