Detail Information

Basic Information:


  VIRBase ID:  

HHID00108572

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548h-5p:           NUP50:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548h-5p NUP50
miRBase
Accession/Entrez ID		 MIMAT0005928 10762
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - NPAP60//NPAP60L

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548h-5p
rs1423828980 chr14:64095086    C/T
rs144194694 chr14:64095094    G/A
rs377270470 chr14:64095095    C/A
rs377270470 chr14:64095095    C/T
rs573600271 chr14:64095093    C/T
rs1000965353 chr16:11306498    A/G
rs1307745356 chr16:11306500    C/T
rs1353674605 chr16:11306491    G/A
rs1353674605 chr16:11306491    G/T
rs149601213 chr16:11306499    C/T
rs563549339 chr16:11306501    G/A
rs956694910 chr16:11306502    C/T
rs988390663 chr16:11306503    G/A
rs1247348117 chr17:13543606    C/T
rs1307196788 chr17:13543599    CAA/C
rs1341303954 chr17:13543598    A/AAAGTAATAG
rs1348342088 chr17:13543609    G/A
rs9913045 chr17:13543607    G/A
rs1285835311 chr8:27048929    A/G
rs1295636494 chr8:27048928    CA/C
rs1306358433 chr8:27048936    G/A
rs1352583339 chr8:27048937    C/T
rs1354349512 chr8:27048928    C/T
rs1391960313 chr8:27048933    A/C
rs561726723 chr8:27048935    C/T
rs748156409 chr8:27048926    G/A
rs748156409 chr8:27048926    G/T
rs1042357839 chr6:131792184    G/A
rs1225605725 chr6:131792194    T/C
rs1257986495 chr6:131792187    G/A
rs1345907099 chr6:131792186    G/T
rs1466227719 chr6:131792183    C/A
rs1466227719 chr6:131792183    C/T
rs906403807 chr6:131792185    C/A
rs1384709035 chr6:131792178    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NUP50
chr22:45575595(+) A-I      intronic
chr22:45575601(+) A-I      intronic
chr22:45575603(+) A-I      intronic
chr22:45575616(+) A-I      intronic
chr22:45575624(+) A-I      intronic
chr22:45578218(+) A-I      intronic
chr22:45578242(+) A-I      intronic
chr22:45572832(+) A-I      intronic
chr22:45564972(+) A-I      intronic
chr22:45572789(+) A-I      intronic
chr22:45572784(+) A-I      intronic
chr22:45578671(+) A-I      intronic
chr22:45572703(+) A-I      intronic
chr22:45565176(+) A-I      intronic
chr22:45578690(+) A-I      intronic
chr22:45575556(+) A-I      intronic
chr22:45578645(+) A-I      intronic
chr22:45578586(+) A-I      intronic
chr22:45578570(+) A-I      intronic
chr22:45578569(+) A-I      intronic
chr22:45578207(+) A-I      intronic
chr22:45578135(+) A-I      intronic
chr22:45576396(+) A-I      intronic
chr22:45578687(+) A-I      intronic
chr22:45573191(+) A-I      intronic
chr22:45572860(+) A-I      intronic
chr22:45562365(+) A-I      intronic
chr22:45575584(+) A-I      intronic
chr22:45576384(+) A-I      intronic
chr22:45578202(+) A-I      intronic
chr22:45565128(+) A-I      intronic
chr22:45578766(+) A-I      intronic
chr22:45565130(+) A-I      intronic
chr22:45578249(+) A-I      intronic
chr22:45575551(+) A-I      intronic
chr22:45578305(+) A-I      intronic
chr22:45572740(+) A-I      intronic
chr22:45572883(+) A-I      intronic
chr22:45578083(+) A-I      intronic
chr22:45573262(+) A-I      intronic
chr22:45578767(+) A-I      intronic
chr22:45576420(+) A-I      intronic
chr22:45576302(+) A-I      intronic
chr22:45578136(+) A-I      intronic
chr22:45575546(+) A-I      intronic
chr22:45575617(+) A-I      intronic
chr22:45575710(+) A-I      intronic
chr22:45572803(+) A-I      intronic
chr22:45576494(+) A-I      intronic
chr22:45572764(+) A-I      intronic
chr22:45576324(+) A-I      intronic
chr22:45573083(+) A-I      intronic
chr22:45576332(+) A-I      intronic
chr22:45578778(+) A-I      intronic
chr22:45572762(+) A-I      intronic
chr22:45573282(+) A-I      intronic
chr22:45578201(+) A-I      intronic
chr22:45572722(+) A-I      intronic
chr22:45576381(+) A-I      intronic
chr22:45575661(+) A-I      intronic
chr22:45572806(+) A-I      intronic
chr22:45572675(+) A-I      intronic
chr22:45578175(+) A-I      intronic
chr22:45565148(+) A-I      intronic
chr22:45564814(+) A-I      intronic
chr22:45578252(+) A-I      intronic
chr22:45572895(+) A-I      intronic
chr22:45578091(+) A-I      intronic
chr22:45564882(+) A-I      intronic
chr22:45575615(+) A-I      intronic
chr22:45572723(+) A-I      intronic
chr22:45562188(+) A-I      intronic
chr22:45578193(+) A-I      intronic
chr22:45576456(+) A-I      intronic
chr22:45575534(+) A-I      intronic
chr22:45575620(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED NUP50
chr22:45573746(+) A-I intron -    15342557   //15258596
chr22:45573798(+) A-I intron -    15342557   //15258596
chr22:45573860(+) A-I intron -    15342557   //15258596
chr22:45573887(+) A-I intron -    15342557   //15258596
chr22:45573896(+) A-I intron -    15342557   //15258596
chr22:45573939(+) A-I intron -    15342557   //15258596
chr22:45574107(+) A-I intron -    15342557
chr22:45579422(+) A-I intron -    15342557
chr22:45572723(+) A-I intron -    21960545   //22327324
chr22:45573314(+) A-I intron -    22327324
chr22:45572675(+) A-G intron -    22484847
chr22:45572723(+) A-G intron -    22484847
chr22:45572764(+) A-G intron -    22484847
chr22:45572895(+) A-G intron -    22484847
chr22:45573083(+) A-G intron -    22484847
chr22:45573203(+) A-G intron -    22484847
chr22:45573271(+) A-G intron -    22484847
chr22:45573754(+) A-G intron -    22484847
chr22:45573759(+) C-A intron -    22484847
chr22:45573798(+) A-G intron -    22484847
chr22:45573848(+) A-G intron -    22484847
chr22:45573855(+) A-G intron -    22484847
chr22:45573856(+) A-G intron -    22484847
chr22:45573860(+) A-G intron -    22484847
chr22:45573886(+) A-G intron -    22484847
chr22:45573887(+) A-G intron -    22484847
chr22:45573896(+) A-G intron -    22484847
chr22:45573939(+) A-G intron -    22484847
chr22:45573956(+) A-G intron -    22484847
chr22:45575534(+) A-G intron -    22484847
chr22:45575551(+) A-G intron -    22484847
chr22:45575584(+) A-G intron -    22484847
chr22:45575620(+) A-G intron -    22484847
chr22:45575646(+) A-G intron -    22484847
chr22:45575707(+) A-G intron -    22484847
chr22:45576420(+) A-G intron -    22484847
chr22:45578305(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NUP50
chr22:45559944-45559945(+) m6A 5'UTR//exon       22575960
chr22:45559969-45559970(+) m6A 5'UTR//exon       22575960
chr22:45560145-45560146(+) m6A 5'UTR//exon       -
chr22:45564056-45564057(+) m6A 5'UTR//exon//intron       24981863
chr22:45564084-45564085(+) m6A 5'UTR//CDS//exon//intron       -
chr22:45567038-45567039(+) m6A 3'UTR//5'UTR//exon//intron       24981863
chr22:45567486-45567487(+) m6A 3'UTR//5'UTR//CDS//exon//intron       24981863
chr22:45571881-45571882(+) m6A 3'UTR//CDS//exon//intron       24284625
chr22:45571895-45571896(+) m6A CDS//exon//intron       24284625
chr22:45571918-45571919(+) Y CDS//exon//intron       26075521
chr22:45573624-45573625(+) m6A exon//intron       24284625
chr22:45574174-45574175(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863
chr22:45574184-45574185(+) m6A 3'UTR//CDS//exon//intron       24284625//24981863
chr22:45574268-45574269(+) m6A 3'UTR//CDS//exon//intron       24284625//25456834//24981863//22608085
chr22:45574310-45574311(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22608085
chr22:45574343-45574344(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22608085
chr22:45574364-45574365(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22608085
chr22:45574371-45574372(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22608085
chr22:45574385-45574386(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22608085
chr22:45574432-45574433(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22608085
chr22:45574504-45574505(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//24981863//27773535//22608085
chr22:45574556-45574557(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//24981863//22608085
chr22:45574673-45574674(+) m6A 3'UTR//CDS//exon//intron       24981863
chr22:45574710-45574711(+) m6A 3'UTR//CDS//exon//intron       -
chr22:45574737-45574738(+) m6A 3'UTR//CDS//exon//intron       -
chr22:45576115-45576116(+) m6A exon//intron       -
chr22:45576142-45576143(+) m6A exon//intron       -
chr22:45579288-45579289(+) m6A CDS//exon       24981863
chr22:45579305-45579306(+) m6A CDS//exon       24981863
chr22:45579348-45579349(+) m6A CDS//exon       24981863
chr22:45579367-45579368(+) m6A CDS//exon       24981863
chr22:45579844-45579845(+) m6A exon//intron       27773535
chr22:45579865-45579866(+) m6A exon//intron       27773535
chr22:45579993-45579994(+) m6A exon//intron       -
chr22:45580479-45580480(+) m6A CDS//exon       24284625//24981863//22608085
chr22:45580536-45580537(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr22:45580634-45580635(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr22:45580652-45580653(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr22:45580685-45580686(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085
chr22:45580710-45580711(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085
chr22:45580732-45580733(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085
chr22:45580798-45580799(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr22:45580824-45580825(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr22:45580913-45580914(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr22:45580986-45580987(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr22:45581007-45581008(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr22:45581145-45581146(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr22:45581174-45581175(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr22:45581248-45581249(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr22:45581332-45581333(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr22:45581359-45581360(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr22:45581420-45581421(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr22:45581481-45581482(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr22:45581519-45581520(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr22:45581538-45581539(+) m6A 3'UTR       24209618//25456834//24981863//22608085
chr22:45581973-45581974(+) m6A 3'UTR       27773535
chr22:45582131-45582132(+) m6A 3'UTR       22575960
chr22:45582312-45582313(+) m6A 3'UTR       24284625
chr22:45582322-45582323(+) m6A 3'UTR       24284625
chr22:45582403-45582404(+) m6A 3'UTR       24284625
chr22:45583067-45583068(+) m6A 3'UTR       22608085
chr22:45583149-45583150(+) m6A 3'UTR       22608085
chr22:45583205-45583206(+) m6A 3'UTR       22608085
chr22:45583504-45583505(+) m6A 3'UTR       -
chr22:45583512-45583513(+) m6A 3'UTR       -
chr22:45583618-45583619(+) m6A 3'UTR       27773535
chr22:45583670-45583671(+) m6A 3'UTR       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548h-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
NUP50
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548h-5p
Interactor2: NUP50

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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