Detail Information

Basic Information:


  VIRBase ID:  

HHID00108559

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548h-5p:           UBE2A:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548h-5p UBE2A
miRBase
Accession/Entrez ID		 MIMAT0005928 7319
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HHR6A//MRXS30//MRXSN//RAD6A//UBC2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548h-5p
rs1423828980 chr14:64095086    C/T
rs144194694 chr14:64095094    G/A
rs377270470 chr14:64095095    C/A
rs377270470 chr14:64095095    C/T
rs573600271 chr14:64095093    C/T
rs1000965353 chr16:11306498    A/G
rs1307745356 chr16:11306500    C/T
rs1353674605 chr16:11306491    G/A
rs1353674605 chr16:11306491    G/T
rs149601213 chr16:11306499    C/T
rs563549339 chr16:11306501    G/A
rs956694910 chr16:11306502    C/T
rs988390663 chr16:11306503    G/A
rs1247348117 chr17:13543606    C/T
rs1307196788 chr17:13543599    CAA/C
rs1341303954 chr17:13543598    A/AAAGTAATAG
rs1348342088 chr17:13543609    G/A
rs9913045 chr17:13543607    G/A
rs1285835311 chr8:27048929    A/G
rs1295636494 chr8:27048928    CA/C
rs1306358433 chr8:27048936    G/A
rs1352583339 chr8:27048937    C/T
rs1354349512 chr8:27048928    C/T
rs1391960313 chr8:27048933    A/C
rs561726723 chr8:27048935    C/T
rs748156409 chr8:27048926    G/A
rs748156409 chr8:27048926    G/T
rs1042357839 chr6:131792184    G/A
rs1225605725 chr6:131792194    T/C
rs1257986495 chr6:131792187    G/A
rs1345907099 chr6:131792186    G/T
rs1466227719 chr6:131792183    C/A
rs1466227719 chr6:131792183    C/T
rs906403807 chr6:131792185    C/A
rs1384709035 chr6:131792178    G/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase UBE2A
chrX:118708527-118708528(+) m6A 5'UTR//exon       24284625//25456834//24981863
chrX:118708629-118708630(+) m6A 5'UTR//exon       24284625//25456834//24981863//22575960
chrX:118708636-118708637(+) m6A 5'UTR//exon       24284625//25456834//24981863//22575960
chrX:118708708-118708709(+) m6A 5'UTR//CDS//exon       24284625//22575960
chrX:118708722-118708723(+) m6A 5'UTR//intron       -
chrX:118708910-118708911(+) m6A 5'UTR//CDS//exon       24284625//22575960
chrX:118717383-118717384(+) m6A 3'UTR//exon//intron       24981863
chrX:118717393-118717394(+) m6A 3'UTR//exon//intron       24981863
chrX:118717944-118717945(+) m6A 3'UTR//exon//intron       -
chrX:118718024-118718025(+) m6A 3'UTR//exon//intron       -
chrX:118718094-118718095(+) m6A 3'UTR//exon//intron       -
chrX:118724480-118724481(+) m6A 3'UTR       -
chrX:118724539-118724540(+) m6A 3'UTR       -
chrX:118724603-118724604(+) m6A 3'UTR       -
chrX:118724894-118724895(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548h-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
UBE2A
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548h-5p
Interactor2: UBE2A

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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