Basic Information:

  VIRBase ID:  

HHID00108556

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548h-5p:  MIMAT0005928          STYX:  NM_001130701     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548h-5p	STYX
miRBase Accession/Entrez ID	MIMAT0005928	6815
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548h-5p	rs1423828980 chr14:64095086    C/T rs144194694 chr14:64095094    G/A rs377270470 chr14:64095095    C/A rs377270470 chr14:64095095    C/T rs573600271 chr14:64095093    C/T rs1000965353 chr16:11306498    A/G rs1307745356 chr16:11306500    C/T rs1353674605 chr16:11306491    G/A rs1353674605 chr16:11306491    G/T rs149601213 chr16:11306499    C/T rs563549339 chr16:11306501    G/A rs956694910 chr16:11306502    C/T rs988390663 chr16:11306503    G/A rs1247348117 chr17:13543606    C/T rs1307196788 chr17:13543599    CAA/C rs1341303954 chr17:13543598    A/AAAGTAATAG rs1348342088 chr17:13543609    G/A rs9913045 chr17:13543607    G/A rs1285835311 chr8:27048929    A/G rs1295636494 chr8:27048928    CA/C rs1306358433 chr8:27048936    G/A rs1352583339 chr8:27048937    C/T rs1354349512 chr8:27048928    C/T rs1391960313 chr8:27048933    A/C rs561726723 chr8:27048935    C/T rs748156409 chr8:27048926    G/A rs748156409 chr8:27048926    G/T rs1042357839 chr6:131792184    G/A rs1225605725 chr6:131792194    T/C rs1257986495 chr6:131792187    G/A rs1345907099 chr6:131792186    G/T rs1466227719 chr6:131792183    C/A rs1466227719 chr6:131792183    C/T rs906403807 chr6:131792185    C/A rs1384709035 chr6:131792178    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	STYX	chr14:53240752(+) A-I      3'UTR chr14:53240746(+) A-I      3'UTR chr14:53240731(+) A-I      3'UTR chr14:53240716(+) A-I      3'UTR chr14:53240723(+) A-I      3'UTR chr14:53200519(+) A-I      intronic chr14:53222851(+) A-I      intronic chr14:53222805(+) A-I      intronic chr14:53222807(+) A-I      intronic chr14:53222812(+) A-I      intronic chr14:53240761(+) A-I      3'UTR chr14:53222830(+) A-I      intronic chr14:53210088(+) A-I      intronic chr14:53210120(+) A-I      intronic chr14:53210184(+) A-I      intronic chr14:53210188(+) A-I      intronic chr14:53210561(+) A-I      intronic chr14:53214551(+) A-I      intronic chr14:53214630(+) A-I      intronic chr14:53218780(+) A-I      intronic chr14:53218803(+) A-I      intronic chr14:53218805(+) A-I      intronic chr14:53218866(+) A-I      intronic chr14:53218925(+) A-I      intronic chr14:53219085(+) A-I      intronic chr14:53219098(+) A-I      intronic chr14:53219869(+) A-I      intronic chr14:53222764(+) A-I      intronic chr14:53222876(+) A-I      intronic chr14:53227804(+) A-I      intronic chr14:53227939(+) A-I      intronic chr14:53228032(+) A-I      intronic chr14:53228036(+) A-I      intronic chr14:53228837(+) A-I      intronic chr14:53223657(+) A-I      intronic chr14:53199440(+) A-I      intronic chr14:53218799(+) A-I      intronic chr14:53222115(+) A-I      intronic chr14:53206383(+) A-I      intronic chr14:53228787(+) A-I      intronic chr14:53222969(+) A-I      intronic chr14:53226658(+) A-I      intronic chr14:53199390(+) A-I      intronic chr14:53206439(+) A-I      intronic chr14:53222815(+) A-I      intronic chr14:53210045(+) A-I      intronic chr14:53199589(+) A-I      intronic chr14:53199624(+) A-I      intronic chr14:53201576(+) A-I      intronic chr14:53210679(+) A-I      intronic chr14:53201625(+) A-I      intronic chr14:53201628(+) A-I      intronic chr14:53210609(+) A-I      intronic chr14:53204555(+) A-I      intronic chr14:53204564(+) A-I      intronic chr14:53204574(+) A-I      intronic chr14:53204633(+) A-I      intronic chr14:53206486(+) A-I      intronic chr14:53223019(+) A-I      intronic chr14:53206612(+) A-I      intronic chr14:53206621(+) A-I      intronic chr14:53206622(+) A-I      intronic chr14:53206800(+) A-I      intronic chr14:53206811(+) A-I      intronic chr14:53206888(+) A-I      intronic chr14:53210044(+) A-I      intronic chr14:53206454(+) A-I      intronic chr14:53226654(+) A-I      intronic chr14:53199518(+) A-I      intronic chr14:53214524(+) A-I      intronic chr14:53206564(+) A-I      intronic chr14:53222968(+) A-I      intronic chr14:53208285(+) A-I      intronic chr14:53198753(+) A-I      intronic chr14:53215080(+) A-I      intronic chr14:53222846(+) A-I      intronic chr14:53219954(+) A-I      intronic chr14:53206477(+) A-I      intronic chr14:53218695(+) A-I      intronic chr14:53204659(+) A-I      intronic chr14:53214590(+) A-I      intronic chr14:53210031(+) A-I      intronic chr14:53210669(+) A-I      intronic chr14:53219193(+) A-I      intronic chr14:53206914(+) A-I      intronic chr14:53198767(+) A-I      intronic chr14:53206552(+) A-I      intronic chr14:53204563(+) A-I      intronic chr14:53222873(+) A-I      intronic chr14:53218940(+) A-I      intronic chr14:53210178(+) A-I      intronic chr14:53219001(+) A-I      intronic chr14:53226777(+) A-I      intronic chr14:53218758(+) A-I      intronic chr14:53222910(+) A-I      intronic chr14:53231570(+) A-I      intronic chr14:53228035(+) A-I      intronic chr14:53232840(+) A-I      intronic chr14:53227966(+) A-I      intronic chr14:53218719(+) A-I      intronic chr14:53206923(+) A-I      intronic chr14:53210685(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	STYX	chr14:53240231(+) G-T intron -    21725310 chr14:53214590(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	STYX	chr14:53197036-53197037(+) m6A 5'UTR//intron       24284625 chr14:53237764-53237765(+) m6A CDS//intron       24981863//22575960 chr14:53237791-53237792(+) m6A CDS//intron       24981863 chr14:53237907-53237908(+) m6A 3'UTR//intron       24284625//24981863 chr14:53237946-53237947(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr14:53237990-53237991(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr14:53238036-53238037(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr14:53238081-53238082(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr14:53238095-53238096(+) m6A 3'UTR//intron       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548h-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	STYX	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548h-5p
Interactor2: STYX

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.