Basic Information:

  VIRBase ID:  

HHID00108544

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548h-5p:  MIMAT0005928          EPHA3:  NM_005233     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548h-5p	EPHA3
miRBase Accession/Entrez ID	MIMAT0005928	2042
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	EK4//ETK//ETK1//HEK//HEK4//TYRO4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548h-5p	rs1423828980 chr14:64095086    C/T rs144194694 chr14:64095094    G/A rs377270470 chr14:64095095    C/A rs377270470 chr14:64095095    C/T rs573600271 chr14:64095093    C/T rs1000965353 chr16:11306498    A/G rs1307745356 chr16:11306500    C/T rs1353674605 chr16:11306491    G/A rs1353674605 chr16:11306491    G/T rs149601213 chr16:11306499    C/T rs563549339 chr16:11306501    G/A rs956694910 chr16:11306502    C/T rs988390663 chr16:11306503    G/A rs1247348117 chr17:13543606    C/T rs1307196788 chr17:13543599    CAA/C rs1341303954 chr17:13543598    A/AAAGTAATAG rs1348342088 chr17:13543609    G/A rs9913045 chr17:13543607    G/A rs1285835311 chr8:27048929    A/G rs1295636494 chr8:27048928    CA/C rs1306358433 chr8:27048936    G/A rs1352583339 chr8:27048937    C/T rs1354349512 chr8:27048928    C/T rs1391960313 chr8:27048933    A/C rs561726723 chr8:27048935    C/T rs748156409 chr8:27048926    G/A rs748156409 chr8:27048926    G/T rs1042357839 chr6:131792184    G/A rs1225605725 chr6:131792194    T/C rs1257986495 chr6:131792187    G/A rs1345907099 chr6:131792186    G/T rs1466227719 chr6:131792183    C/A rs1466227719 chr6:131792183    C/T rs906403807 chr6:131792185    C/A rs1384709035 chr6:131792178    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	EPHA3	chr3:89430734(+) A-I      intronic chr3:89344906(+) A-I      intronic chr3:89508111(+) A-I      intronic chr3:89321098(+) A-I      intronic chr3:89483620(+) A-I      intronic chr3:89347092(+) A-I      intronic chr3:89508895(+) A-I      intronic chr3:89448096(+) A-I      intronic chr3:89483588(+) A-I      intronic chr3:89344898(+) A-I      intronic chr3:89484517(+) A-I      intronic chr3:89484492(+) A-I      intronic chr3:89484534(+) A-I      intronic chr3:89430751(+) A-I      intronic chr3:89483589(+) A-I      intronic chr3:89321082(+) A-I      intronic chr3:89321095(+) A-I      intronic chr3:89508278(+) A-I      intronic chr3:89508260(+) A-I      intronic chr3:89219254(+) A-I      intronic chr3:89488533(+) A-I      intronic chr3:89387909(+) A-I      intronic chr3:89388453(+) A-I      intronic chr3:89181933(+) A-I      intronic chr3:89347140(+) A-I      intronic chr3:89484942(+) A-I      intronic chr3:89347038(+) A-I      intronic chr3:89485011(+) A-I      intronic chr3:89499910(+) A-I      intronic chr3:89499875(+) A-I      intronic chr3:89485012(+) A-I      intronic chr3:89387904(+) A-I      intronic chr3:89508718(+) A-I      intronic chr3:89305627(+) A-I      intronic chr3:89508814(+) A-I      intronic chr3:89387838(+) A-I      intronic chr3:89488591(+) A-I      intronic chr3:89483582(+) A-I      intronic chr3:89430761(+) A-I      intronic chr3:89485044(+) A-I      intronic chr3:89484947(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	EPHA3	chr3:89156754-89156755(+) m6A 5'UTR       - chr3:89156778-89156779(+) m6A 5'UTR       24981863//22608085 chr3:89156960-89156961(+) m6A CDS       22608085 chr3:89176378-89176379(+) m6A CDS       22608085 chr3:89259035-89259036(+) m6A CDS       22608085 chr3:89259054-89259055(+) m6A CDS       22608085 chr3:89259079-89259080(+) m6A CDS       22608085 chr3:89259091-89259092(+) m6A CDS       22608085 chr3:89259105-89259106(+) m6A CDS       22608085 chr3:89259124-89259125(+) m6A CDS       22608085 chr3:89259169-89259170(+) m6A CDS       22608085 chr3:89259198-89259199(+) m6A CDS       22608085 chr3:89259210-89259211(+) m6A CDS       22608085 chr3:89259331-89259332(+) m6A CDS       22608085 chr3:89259496-89259497(+) m6A CDS       22608085 chr3:89259511-89259512(+) m6A CDS       22608085 chr3:89390948-89390949(+) m6A CDS       22608085 chr3:89390964-89390965(+) m6A CDS       22608085 chr3:89390982-89390983(+) m6A CDS       22608085 chr3:89391046-89391047(+) m6A CDS       22608085 chr3:89528717-89528718(+) m6A 3'UTR       22608085 chr3:89528765-89528766(+) m6A 3'UTR       22608085 chr3:89528808-89528809(+) m6A 3'UTR       22608085 chr3:89528925-89528926(+) m6A 3'UTR       22608085 chr3:89528950-89528951(+) m6A 3'UTR       22608085 chr3:89528971-89528972(+) m6A 3'UTR       22608085 chr3:89528992-89528993(+) m6A 3'UTR       22608085 chr3:89529031-89529032(+) m6A 3'UTR       22608085 chr3:89529119-89529120(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548h-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Cell line (HEK-293|HeLa)     22984580
	EPHA3	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548h-5p
Interactor2: EPHA3

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.