Detail Information

Basic Information:


  VIRBase ID:  

HHID00108429

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548d-5p:           GPATCH11:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548d-5p GPATCH11
miRBase
Accession/Entrez ID		 MIMAT0004812 253635
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CCDC75//CENP-Y//CENPY

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548d-5p
rs1240978917 chr8:123348085    G/A
rs1370161434 chr8:123348096    C/A
rs1423052174 chr8:123348086    G/A
rs1039169216 chr17:67471540    G/A
rs1039169216 chr17:67471540    G/T
rs543252291 chr17:67471553    A/G
rs1196924094 chr8:123348101    A/G
rs756308753 chr8:123348103    T/C
rs768094101 chr17:67471554    T/G
rs899430888 chr17:67471556    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR GPATCH11
chr2:37315709(+) A-I      intronic
chr2:37315714(+) A-I      intronic
chr2:37315855(+) A-I      intronic
chr2:37315682(+) A-I      intronic
chr2:37315728(+) A-I      intronic
chr2:37318642(+) A-I      intronic
chr2:37315854(+) A-I      intronic
chr2:37316603(+) A-I      intronic
chr2:37315762(+) A-I      intronic
chr2:37315669(+) A-I      intronic
chr2:37315862(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase GPATCH11
chr2:37311688-37311689(+) m6A 5'UTR//CDS       24981863
chr2:37315534-37315535(+) m6A 5'UTR//CDS//exon       24981863
chr2:37315546-37315547(+) m1A 5'UTR//CDS//exon       26863196
chr2:37315552-37315553(+) m6A 5'UTR//CDS//exon       24981863
chr2:37316794-37316795(+) m6A CDS//intron       24981863//27773535
chr2:37316871-37316872(+) m6A CDS//intron       24981863//27773535//22608085
chr2:37316899-37316900(+) m6A CDS//intron       24981863//27773535//22608085
chr2:37316946-37316947(+) m6A CDS//intron       24981863//27773535//22608085
chr2:37317839-37317840(+) m6A CDS//intron       24981863
chr2:37317861-37317862(+) m6A CDS//intron       24981863
chr2:37319145-37319146(+) m6A CDS//exon       24981863
chr2:37319170-37319171(+) m6A CDS//exon       24981863
chr2:37321275-37321276(+) m6A CDS//exon       24981863//27773535//22608085
chr2:37321301-37321302(+) m6A CDS//exon       24981863//27773535//22608085
chr2:37323512-37323513(+) m6A 3'UTR       27773535//22608085
chr2:37323596-37323597(+) m6A 3'UTR       24981863//27773535//22608085
chr2:37323617-37323618(+) m6A 3'UTR       24981863//27773535//22575960//22608085
chr2:37323663-37323664(+) m6A 3'UTR       24981863//27773535//22608085
chr2:37323703-37323704(+) m6A 3'UTR       24981863//27773535//22608085
chr2:37323768-37323769(+) m6A 3'UTR       24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548d-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
GPATCH11
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-548d-5p
Atorvastatin 60823 Drug interaction    RC00007234
D-Glucose 5793 Drug interaction    RC00007233
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007232
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-548d-5p
Etoposide 36462       23028896

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548d-5p
Interactor2: GPATCH11

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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