Detail Information

Basic Information:


  VIRBase ID:  

HHID00108407

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548d-5p:           AIDA:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548d-5p AIDA
miRBase
Accession/Entrez ID		 MIMAT0004812 64853
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C1orf80

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548d-5p
rs1240978917 chr8:123348085    G/A
rs1370161434 chr8:123348096    C/A
rs1423052174 chr8:123348086    G/A
rs1039169216 chr17:67471540    G/A
rs1039169216 chr17:67471540    G/T
rs543252291 chr17:67471553    A/G
rs1196924094 chr8:123348101    A/G
rs756308753 chr8:123348103    T/C
rs768094101 chr17:67471554    T/G
rs899430888 chr17:67471556    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR AIDA
chr1:222862689(-) A-I      intronic
chr1:222874480(-) A-I      intronic
chr1:222874481(-) A-I      intronic
chr1:222874478(-) A-I      intronic
chr1:222874473(-) A-I      intronic
chr1:222874493(-) A-I      intronic
chr1:222862577(-) A-I      intronic
chr1:222862600(-) A-I      intronic
chr1:222862663(-) A-I      intronic
chr1:222862664(-) A-I      intronic
chr1:222862670(-) A-I      intronic
chr1:222857720(-) A-I      intronic
chr1:222874487(-) A-I      intronic
chr1:222875233(-) A-I      intronic
chr1:222854785(-) A-I      intronic
chr1:222881891(-) A-I      intronic
chr1:222847372(-) A-I      intronic
chr1:222881954(-) A-I      intronic
chr1:222857672(-) A-I      intronic
chr1:222862562(-) A-I      intronic
chr1:222854776(-) A-I      intronic
chr1:222854801(-) A-I      intronic
chr1:222875225(-) A-I      intronic
chr1:222854865(-) A-I      intronic
chr1:222861467(-) A-I      intronic
chr1:222861480(-) A-I      intronic
chr1:222861450(-) A-I      intronic
chr1:222875191(-) A-I      intronic
chr1:222875204(-) A-I      intronic
chr1:222861486(-) A-I      intronic
chr1:222882518(-) A-I      intronic
chr1:222880648(-) A-I      intronic
chr1:222880055(-) A-I      intronic
chr1:222862115(-) A-I      intronic
chr1:222857523(-) A-I      intronic
chr1:222870422(-) A-I      intronic
chr1:222879954(-) A-I      intronic
chr1:222880159(-) A-I      intronic
chr1:222880031(-) A-I      intronic
chr1:222881815(-) A-I      intronic
chr1:222854918(-) A-I      intronic
chr1:222881848(-) A-I      intronic
chr1:222871972(-) A-I      intronic
chr1:222854919(-) A-I      intronic
chr1:222862110(-) A-I      intronic
chr1:222862106(-) A-I      intronic
chr1:222880693(-) A-I      intronic
chr1:222861440(-) A-I      intronic
chr1:222862136(-) A-I      intronic
chr1:222862070(-) A-I      intronic
chr1:222854803(-) A-I      intronic
chr1:222862634(-) A-I      intronic
chr1:222880646(-) A-I      intronic
chr1:222861994(-) A-I      intronic
chr1:222862660(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED AIDA
chr1:222870422(-) A-G intron -    22484847
chr1:222873967(-) C-T intron -    22484847
chr1:222880646(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AIDA
chr1:222841396-222841397(-) m6A 3'UTR//exon       27773535
chr1:222841472-222841473(-) m6A 3'UTR//exon       27773535
chr1:222841504-222841505(-) m6A 3'UTR//exon       27773535
chr1:222841524-222841525(-) m6A 3'UTR//exon       27773535
chr1:222843122-222843123(-) m6A 3'UTR//exon       24981863
chr1:222843183-222843184(-) m6A 3'UTR//exon       24981863
chr1:222843212-222843213(-) m6A 3'UTR//exon       24981863//22608085
chr1:222843219-222843220(-) m6A 3'UTR//exon       24981863//22608085
chr1:222843251-222843252(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr1:222843276-222843277(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr1:222843321-222843322(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr1:222843476-222843477(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085
chr1:222843497-222843498(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085
chr1:222843566-222843567(-) m6A CDS//exon//intron       27773535//22608085
chr1:222867134-222867135(-) m6A CDS//exon       24981863
chr1:222867150-222867151(-) m6A CDS//exon       24981863
chr1:222867158-222867159(-) m6A CDS//exon       24981863
chr1:222867601-222867602(-) m6A CDS//exon       24981863
chr1:222876495-222876496(-) m6A CDS//exon       24981863
chr1:222876549-222876550(-) m6A CDS//exon       24981863
chr1:222884796-222884797(-) m6A exon//intron       27773535
chr1:222884825-222884826(-) m6A exon//intron       27773535
chr1:222885063-222885064(-) m6A exon//intron       24981863
chr1:222885320-222885321(-) m6A exon//intron       25456834//24981863//22608085
chr1:222885376-222885377(-) m6A exon//intron       25456834//24981863//22608085
chr1:222885665-222885666(-) m6A 5'UTR//exon//intron       24981863
chr1:222885708-222885709(-) m6A 5'UTR//exon//intron       24981863
chr1:222885981-222885982(-) m6A exon//intron       24284625//24209618//24981863
chr1:222886163-222886164(-) m6A intron       24284625
chr1:222886179-222886180(-) m6A intron       24284625
chr1:222886187-222886188(-) m6A intron       24284625
chr1:222886375-222886376(-) m6A exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548d-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
AIDA
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -
Ribosome-free cytosol Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-548d-5p
Atorvastatin 60823 Drug interaction    RC00007234
D-Glucose 5793 Drug interaction    RC00007233
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007232
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-548d-5p
Etoposide 36462       23028896

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548d-5p
Interactor2: AIDA

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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