Detail Information

Basic Information:


  VIRBase ID:  

HHID00108391

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548d-5p:           HECA:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548d-5p HECA
miRBase
Accession/Entrez ID		 MIMAT0004812 51696
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - dJ225E12.1//HDC//HDCL//HHDC

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548d-5p
rs1240978917 chr8:123348085    G/A
rs1370161434 chr8:123348096    C/A
rs1423052174 chr8:123348086    G/A
rs1039169216 chr17:67471540    G/A
rs1039169216 chr17:67471540    G/T
rs543252291 chr17:67471553    A/G
rs1196924094 chr8:123348101    A/G
rs756308753 chr8:123348103    T/C
rs768094101 chr17:67471554    T/G
rs899430888 chr17:67471556    A/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR HECA
chr6:139462990(+) A-I      intronic
chr6:139462914(+) A-I      intronic
chr6:139461947(+) A-I      intronic
chr6:139479236(+) A-I      intronic
chr6:139477556(+) A-I      intronic
chr6:139477544(+) A-I      intronic
chr6:139477537(+) A-I      intronic
chr6:139463965(+) A-I      intronic
chr6:139468587(+) A-I      intronic
chr6:139464887(+) A-I      intronic
chr6:139477479(+) A-I      intronic
chr6:139464822(+) A-I      intronic
chr6:139463806(+) A-I      intronic
chr6:139464877(+) A-I      intronic
chr6:139468563(+) A-I      intronic
chr6:139474653(+) A-I      intronic
chr6:139477581(+) A-I      intronic
chr6:139468507(+) A-I      intronic
chr6:139468521(+) A-I      intronic
chr6:139464812(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED HECA
chr6:139463270(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase HECA
chr6:139456412-139456413(+) m6A 5'UTR       24209618
chr6:139456549-139456550(+) m6A CDS       24209618//27371828
chr6:139456570-139456571(+) m6A CDS       24209618//27371828
chr6:139487468-139487469(+) m6A CDS       24209618
chr6:139487633-139487634(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139487641-139487642(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139487711-139487712(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085
chr6:139487717-139487718(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085
chr6:139487777-139487778(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085
chr6:139487885-139487886(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085
chr6:139487894-139487895(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085
chr6:139488153-139488154(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488191-139488192(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488201-139488202(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488233-139488234(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488284-139488285(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488338-139488339(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:139488375-139488376(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr6:139488397-139488398(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr6:139488420-139488421(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr6:139495525-139495526(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr6:139495554-139495555(+) m6A CDS       -
chr6:139500156-139500157(+) m6A 3'UTR       26404942
chr6:139500211-139500212(+) m6A 3'UTR       26404942
chr6:139500249-139500250(+) m6A 3'UTR       26404942
chr6:139500265-139500266(+) m6A 3'UTR       26404942
chr6:139500591-139500592(+) m6A 3'UTR       26404942
chr6:139500641-139500642(+) m6A 3'UTR       26404942
chr6:139501402-139501403(+) m6A 3'UTR       26404942
chr6:139501410-139501411(+) m6A 3'UTR       26404942
chr6:139501423-139501424(+) m6A 3'UTR       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548d-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
HECA
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-548d-5p
Atorvastatin 60823 Drug interaction    RC00007234
D-Glucose 5793 Drug interaction    RC00007233
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007232
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-548d-5p
Etoposide 36462       23028896

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548d-5p
Interactor2: HECA

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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