Basic Information:

  VIRBase ID:  

HHID00108339

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548c-5p:  MIMAT0004806          C6orf120:  NM_001317342     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548c-5p	C6orf120
miRBase Accession/Entrez ID	MIMAT0004806	387263
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548c-5p	rs1188707087 chr12:64622544    C/A rs1188707087 chr12:64622544    C/T rs1371697031 chr12:64622552    G/A rs1391518567 chr12:64622541    T/C rs750959106 chr12:64622554    C/T rs1202383522 chr12:64622535    A/G rs374151873 chr12:64622540    A/G rs540698062 chr12:64622545    G/A rs764336601 chr12:64622536    A/C

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	C6orf120	chr6:170102415-170102416(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr6:170102431-170102432(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr6:170102455-170102456(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr6:170102476-170102477(+) m6A 5'UTR       24284625//25456834//24981863//22608085 chr6:170102712-170102713(+) m6A CDS       24284625//22608085 chr6:170102733-170102734(+) m6A CDS       24284625//22608085 chr6:170102914-170102915(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr6:170103106-170103107(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr6:170103158-170103159(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr6:170103195-170103196(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr6:170103345-170103346(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr6:170103365-170103366(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085 chr6:170103571-170103572(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr6:170103790-170103791(+) m6A 3'UTR       24981863//22608085 chr6:170104346-170104347(+) m6A 3'UTR       24981863//22608085 chr6:170104430-170104431(+) m6A 3'UTR       24981863//26404942//22608085 chr6:170104465-170104466(+) m6A 3'UTR       24284625//24981863//26404942//22608085 chr6:170104491-170104492(+) m6A 3'UTR       24284625//24981863//22608085 chr6:170104519-170104520(+) m6A 3'UTR       24284625//24981863//22608085 chr6:170104604-170104605(+) m6A 3'UTR       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548c-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Urine     -
	C6orf120	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-548c-5p	Emodin 3220 Drug interaction    RC00007211 Sorafenib 216239 Drug interaction    RC00007212

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-548c-5p	l-685,458       5479543

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548c-5p
Interactor2: C6orf120

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.