Detail Information

Basic Information:


  VIRBase ID:  

HHID00108337

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548c-5p:           ZDHHC21:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548c-5p ZDHHC21
miRBase
Accession/Entrez ID		 MIMAT0004806 340481
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DHHC-21//DHHC21//DNZ1//HSPC097

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548c-5p
rs1188707087 chr12:64622544    C/A
rs1188707087 chr12:64622544    C/T
rs1371697031 chr12:64622552    G/A
rs1391518567 chr12:64622541    T/C
rs750959106 chr12:64622554    C/T
rs1202383522 chr12:64622535    A/G
rs374151873 chr12:64622540    A/G
rs540698062 chr12:64622545    G/A
rs764336601 chr12:64622536    A/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZDHHC21
chr9:14689039(-) A-I      intronic
chr9:14689845(-) A-I      intronic
chr9:14689851(-) A-I      intronic
chr9:14689036(-) A-I      intronic
chr9:14681342(-) A-I      intronic
chr9:14688548(-) A-I      intronic
chr9:14689022(-) A-I      intronic
chr9:14643040(-) A-I      intronic
chr9:14689031(-) A-I      intronic
chr9:14643133(-) A-I      intronic
chr9:14689847(-) A-I      intronic
chr9:14689002(-) A-I      intronic
chr9:14689800(-) A-I      intronic
chr9:14687665(-) A-I      intronic
chr9:14689854(-) A-I      intronic
chr9:14689043(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZDHHC21
chr9:14612633-14612634(-) m6A 3'UTR       24981863
chr9:14612690-14612691(-) m6A 3'UTR       24981863
chr9:14612702-14612703(-) m6A 3'UTR       24981863
chr9:14612710-14612711(-) m6A 3'UTR       24981863
chr9:14615863-14615864(-) m6A 3'UTR       27773535
chr9:14615883-14615884(-) m6A 3'UTR       27773535
chr9:14615953-14615954(-) m6A 3'UTR       27773535
chr9:14617029-14617030(-) m6A 3'UTR       24981863
chr9:14617040-14617041(-) m6A 3'UTR       24981863
chr9:14617125-14617126(-) m6A 3'UTR       24981863
chr9:14617298-14617299(-) m6A 3'UTR       27773535
chr9:14617312-14617313(-) m6A 3'UTR       27773535
chr9:14618326-14618327(-) m6A 3'UTR       27773535
chr9:14618429-14618430(-) m6A 3'UTR       27773535
chr9:14618894-14618895(-) m6A 3'UTR       24981863//22608085
chr9:14618962-14618963(-) m6A 3'UTR       24981863//22608085
chr9:14690374-14690375(-) m6A 5'UTR//exon       25456834//24981863//27371828//27773536
chr9:14693393-14693394(-) m6A 5'UTR       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548c-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Urine     -
ZDHHC21
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-548c-5p
Emodin 3220 Drug interaction    RC00007211
Sorafenib 216239 Drug interaction    RC00007212
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-548c-5p
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548c-5p
Interactor2: ZDHHC21

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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