Detail Information

Basic Information:


  VIRBase ID:  

HHID00108326

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548c-5p:           NRG4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548c-5p NRG4
miRBase
Accession/Entrez ID		 MIMAT0004806 145957
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HRG4

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548c-5p
rs1188707087 chr12:64622544    C/A
rs1188707087 chr12:64622544    C/T
rs1371697031 chr12:64622552    G/A
rs1391518567 chr12:64622541    T/C
rs750959106 chr12:64622554    C/T
rs1202383522 chr12:64622535    A/G
rs374151873 chr12:64622540    A/G
rs540698062 chr12:64622545    G/A
rs764336601 chr12:64622536    A/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NRG4
chr15:76259970(-) A-I      intronic
chr15:76259985(-) A-I      intronic
chr15:76293441(-) A-I      intronic
chr15:76259982(-) A-I      intronic
chr15:76259980(-) A-I      intronic
chr15:76260070(-) A-I      intronic
chr15:76287434(-) A-I      intronic
chr15:76241612(-) A-I      intronic
chr15:76241284(-) A-I      intronic
chr15:76283102(-) A-I      intronic
chr15:76241604(-) A-I      intronic
chr15:76241714(-) A-I      intronic
chr15:76281480(-) A-I      intronic
chr15:76283092(-) A-I      intronic
chr15:76293624(-) A-I      intronic
chr15:76292484(-) A-I      intronic
chr15:76241676(-) A-I      intronic
chr15:76241700(-) A-I      intronic
chr15:76240765(-) A-I      intronic
chr15:76246101(-) A-I      intronic
chr15:76241689(-) A-I      intronic
chr15:76283138(-) A-I      intronic
chr15:76241309(-) A-I      intronic
chr15:76241536(-) A-I      intronic
chr15:76240874(-) A-I      intronic
chr15:76245044(-) A-I      intronic
chr15:76241640(-) A-I      intronic
chr15:76280698(-) A-I      intronic
chr15:76283193(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NRG4
chr15:76233371-76233372(-) m6A 3'UTR//intron       24981863//22608085
chr15:76234116-76234117(-) m6A 3'UTR//intron       27773535//22608085
chr15:76234155-76234156(-) m6A 3'UTR//intron       27773535//22608085
chr15:76234408-76234409(-) m6A 3'UTR//intron       27773535
chr15:76234489-76234490(-) m6A 3'UTR//intron       24981863//27773535
chr15:76235206-76235207(-) m6A 3'UTR//intron       27773535
chr15:76235221-76235222(-) m6A 3'UTR//intron       27773535
chr15:76235296-76235297(-) m6A 3'UTR//intron       27773535
chr15:76235392-76235393(-) m6A 3'UTR//intron       24981863//27773535//22575960
chr15:76235398-76235399(-) m6A 3'UTR//intron       24981863//27773535//22575960
chr15:76235525-76235526(-) m6A 3'UTR//intron       24284625//24981863//27773535//22575960
chr15:76235534-76235535(-) m6A 3'UTR//intron       24284625//24981863//27773535//22575960
chr15:76235584-76235585(-) m6A 3'UTR//intron       24284625//24981863//27773535
chr15:76235625-76235626(-) m6A 3'UTR//intron       24284625//24981863//27773535
chr15:76235666-76235667(-) m6A 3'UTR//intron       24284625//27773535//22575960
chr15:76235846-76235847(-) m6A 3'UTR//intron       27773535
chr15:76235921-76235922(-) m6A 3'UTR//exon       27773535
chr15:76235961-76235962(-) m6A 3'UTR//exon       27773535
chr15:76235987-76235988(-) m6A 3'UTR//CDS//exon       27773535
chr15:76238117-76238118(-) m6A exon//intron       27773535
chr15:76238140-76238141(-) m6A exon//intron       27773535
chr15:76243117-76243118(-) m6A intron       27773535
chr15:76243136-76243137(-) m6A intron       27773535
chr15:76243188-76243189(-) m6A intron       27773535
chr15:76243212-76243213(-) m6A intron       27773535
chr15:76243327-76243328(-) m6A intron       27773535
chr15:76243361-76243362(-) m6A intron       27773535
chr15:76303587-76303588(-) m6A 5'UTR       27773535
chr15:76304380-76304381(-) m6A 5'UTR//intron       27773535
chr15:76304385-76304386(-) m6A 5'UTR//intron       27773535
chr15:76304696-76304697(-) m6A 5'UTR//intron       24981863
chr15:76304705-76304706(-) m6A 5'UTR//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548c-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Urine     -
NRG4
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-548c-5p
Emodin 3220 Drug interaction    RC00007211
Sorafenib 216239 Drug interaction    RC00007212
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-548c-5p
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548c-5p
Interactor2: NRG4

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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