Basic Information:

  VIRBase ID:  

HHID00108323

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548c-5p:  MIMAT0004806          C5orf24:  NM_001135586     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548c-5p	C5orf24
miRBase Accession/Entrez ID	MIMAT0004806	134553
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548c-5p	rs1188707087 chr12:64622544    C/A rs1188707087 chr12:64622544    C/T rs1371697031 chr12:64622552    G/A rs1391518567 chr12:64622541    T/C rs750959106 chr12:64622554    C/T rs1202383522 chr12:64622535    A/G rs374151873 chr12:64622540    A/G rs540698062 chr12:64622545    G/A rs764336601 chr12:64622536    A/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	C5orf24	chr5:134185417(+) A-I      intronic chr5:134183913(+) A-I      intronic chr5:134184774(+) A-I      intronic chr5:134183839(+) A-I      intronic chr5:134184127(+) A-I      intronic chr5:134184263(+) A-I      intronic chr5:134189534(+) A-I      intronic chr5:134188971(+) A-I      intronic chr5:134183103(+) A-I      intronic chr5:134184295(+) A-I      intronic chr5:134183115(+) A-I      intronic chr5:134189757(+) A-I      intronic chr5:134189606(+) A-I      intronic chr5:134189619(+) A-I      intronic chr5:134183166(+) A-I      intronic chr5:134189623(+) A-I      intronic chr5:134189685(+) A-I      intronic chr5:134189690(+) A-I      intronic chr5:134183170(+) A-I      intronic chr5:134189691(+) A-I      intronic chr5:134184692(+) A-I      intronic chr5:134185452(+) A-I      intronic chr5:134185577(+) A-I      intronic chr5:134185932(+) A-I      intronic chr5:134186827(+) A-I      intronic chr5:134188627(+) A-I      intronic chr5:134188676(+) A-I      intronic chr5:134183183(+) A-I      intronic chr5:134183446(+) A-I      intronic chr5:134183531(+) A-I      intronic chr5:134183086(+) A-I      intronic chr5:134188734(+) A-I      intronic chr5:134184792(+) A-I      intronic chr5:134188976(+) A-I      intronic chr5:134188582(+) A-I      intronic chr5:134184866(+) A-I      intronic chr5:134184847(+) A-I      intronic chr5:134183065(+) A-I      intronic chr5:134184857(+) A-I      intronic chr5:134187692(+) A-I      intronic chr5:134185373(+) A-I      intronic chr5:134189000(+) A-I      intronic chr5:134184895(+) A-I      intronic chr5:134183017(+) A-I      intronic chr5:134183039(+) A-I      intronic chr5:134183085(+) A-I      intronic chr5:134188525(+) A-I      intronic chr5:134184785(+) A-I      intronic chr5:134185448(+) A-I      intronic chr5:134184500(+) A-I      intronic chr5:134186419(+) A-I      intronic chr5:134185447(+) A-I      intronic chr5:134186219(+) A-I      intronic chr5:134183667(+) A-I      intronic chr5:134184854(+) A-I      intronic chr5:134184240(+) A-I      intronic chr5:134189695(+) A-I      intronic chr5:134183519(+) A-I      intronic chr5:134189643(+) A-I      intronic chr5:134188594(+) A-I      intronic chr5:134186818(+) A-I      intronic chr5:134183060(+) A-I      intronic chr5:134185522(+) A-I      intronic chr5:134192184(+) A-I      3'UTR chr5:134189639(+) A-I      intronic chr5:134189518(+) A-I      intronic chr5:134188601(+) A-I      intronic chr5:134185490(+) A-I      intronic chr5:134185988(+) A-I      intronic chr5:134183571(+) A-I      intronic chr5:134183851(+) A-I      intronic chr5:134183151(+) A-I      intronic chr5:134189301(+) A-I      intronic chr5:134189302(+) A-I      intronic chr5:134184114(+) A-I      intronic chr5:134186828(+) A-I      intronic chr5:134186017(+) A-I      intronic chr5:134183535(+) A-I      intronic chr5:134183880(+) A-I      intronic chr5:134183182(+) A-I      intronic chr5:134183007(+) A-I      intronic chr5:134183849(+) A-I      intronic chr5:134189649(+) A-I      intronic chr5:134184900(+) A-I      intronic chr5:134183825(+) A-I      intronic chr5:134186894(+) A-I      intronic chr5:134183006(+) A-I      intronic chr5:134187700(+) A-I      intronic chr5:134189676(+) A-I      intronic chr5:134184441(+) A-I      intronic chr5:134186280(+) A-I      intronic chr5:134185477(+) A-I      intronic chr5:134189548(+) A-I      intronic chr5:134185968(+) A-I      intronic chr5:134183490(+) A-I      intronic chr5:134185465(+) A-I      intronic chr5:134188551(+) A-I      intronic chr5:134189517(+) A-I      intronic chr5:134183090(+) A-I      intronic chr5:134184865(+) A-I      intronic chr5:134183890(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	C5orf24	chr5:134184864(+) A-I intron -    22327324 chr5:134183006(+) A-G intron -    22484847 chr5:134183060(+) A-G intron -    22484847 chr5:134183090(+) A-G intron -    22484847 chr5:134183444(+) A-G intron -    22484847 chr5:134183519(+) A-G intron -    22484847 chr5:134183571(+) A-G intron -    22484847 chr5:134183791(+) A-G intron -    22484847 chr5:134183825(+) A-G intron -    22484847 chr5:134183838(+) A-G intron -    22484847 chr5:134183842(+) A-G intron -    22484847 chr5:134184780(+) A-G intron -    22484847 chr5:134184785(+) A-G intron -    22484847 chr5:134184864(+) A-G intron -    22484847 chr5:134184894(+) A-G intron -    22484847 chr5:134184901(+) A-G intron -    22484847 chr5:134185447(+) A-G intron -    22484847 chr5:134185448(+) A-G intron -    22484847 chr5:134185490(+) A-G intron -    22484847 chr5:134185939(+) A-G intron -    22484847 chr5:134186419(+) A-G intron -    22484847 chr5:134186828(+) A-G intron -    22484847 chr5:134187700(+) A-G intron -    22484847 chr5:134188525(+) A-G intron -    22484847 chr5:134188551(+) A-G intron -    22484847 chr5:134189302(+) A-G intron -    22484847 chr5:134189695(+) A-G intron -    22484847 chr5:134192096(+) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	C5orf24	chr5:134181417-134181418(+) m6A 5'UTR       24981863 chr5:134181704-134181705(+) m6A 5'UTR//intron       24209618//24981863 chr5:134182535-134182536(+) m6A 5'UTR//intron       24284625//24209618//24981863//22608085 chr5:134190736-134190737(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr5:134190759-134190760(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr5:134190773-134190774(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:134190785-134190786(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:134190820-134190821(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:134190875-134190876(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:134190899-134190900(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:134190913-134190914(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:134190923-134190924(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:134190947-134190948(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr5:134190961-134190962(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr5:134190971-134190972(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr5:134191009-134191010(+) m6A CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr5:134191124-134191125(+) m6A CDS//intron       24209618//24981863//22608085 chr5:134191141-134191142(+) m6A CDS//intron       24209618//24981863//22608085 chr5:134193001-134193002(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr5:134193101-134193102(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr5:134193148-134193149(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr5:134193170-134193171(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr5:134193202-134193203(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr5:134193962-134193963(+) m6A 3'UTR       24981863 chr5:134193993-134193994(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548c-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Urine     -
	C5orf24	Chromatin K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-548c-5p	Emodin 3220 Drug interaction    RC00007211 Sorafenib 216239 Drug interaction    RC00007212

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-548c-5p	l-685,458       5479543

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548c-5p
Interactor2: C5orf24

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.