Detail Information

Basic Information:


  VIRBase ID:  

HHID00108305

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548c-5p:           GOPC:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548c-5p GOPC
miRBase
Accession/Entrez ID		 MIMAT0004806 57120
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CAL//dJ94G16.2//FIG//GOPC1//PIST

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548c-5p
rs1188707087 chr12:64622544    C/A
rs1188707087 chr12:64622544    C/T
rs1371697031 chr12:64622552    G/A
rs1391518567 chr12:64622541    T/C
rs750959106 chr12:64622554    C/T
rs1202383522 chr12:64622535    A/G
rs374151873 chr12:64622540    A/G
rs540698062 chr12:64622545    G/A
rs764336601 chr12:64622536    A/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR GOPC
chr6:117885188(-) A-I      intronic
chr6:117884863(-) A-I      intronic
chr6:117885318(-) A-I      intronic
chr6:117885262(-) A-I      intronic
chr6:117885224(-) A-I      intronic
chr6:117885213(-) A-I      intronic
chr6:117886582(-) A-I      intronic
chr6:117891252(-) A-I      intronic
chr6:117885158(-) A-I      intronic
chr6:117907825(-) A-I      intronic
chr6:117907828(-) A-I      intronic
chr6:117909121(-) A-I      intronic
chr6:117909263(-) A-I      intronic
chr6:117911516(-) A-I      intronic
chr6:117911613(-) A-I      intronic
chr6:117911709(-) A-I      intronic
chr6:117884719(-) A-I      intronic
chr6:117884722(-) A-I      intronic
chr6:117884775(-) A-I      intronic
chr6:117884803(-) A-I      intronic
chr6:117884785(-) A-I      intronic
chr6:117884879(-) A-I      intronic
chr6:117884871(-) A-I      intronic
chr6:117884828(-) A-I      intronic
chr6:117884717(-) A-I      intronic
chr6:117884715(-) A-I      intronic
chr6:117884673(-) A-I      intronic
chr6:117884663(-) A-I      intronic
chr6:117884822(-) A-I      intronic
chr6:117884622(-) A-I      intronic
chr6:117885178(-) A-I      intronic
chr6:117885179(-) A-I      intronic
chr6:117885203(-) A-I      intronic
chr6:117885206(-) A-I      intronic
chr6:117885220(-) A-I      intronic
chr6:117885230(-) A-I      intronic
chr6:117885249(-) A-I      intronic
chr6:117885269(-) A-I      intronic
chr6:117885273(-) A-I      intronic
chr6:117885305(-) A-I      intronic
chr6:117885147(-) A-I      intronic
chr6:117885319(-) A-I      intronic
chr6:117885344(-) A-I      intronic
chr6:117885411(-) A-I      intronic
chr6:117907824(-) A-I      intronic
chr6:117884668(-) A-I      intronic
chr6:117884854(-) A-I      intronic
chr6:117912287(-) A-I      intronic
chr6:117885406(-) A-I      intronic
chr6:117919339(-) A-I      intronic
chr6:117884833(-) A-I      intronic
chr6:117912078(-) A-I      intronic
chr6:117911551(-) A-I      intronic
chr6:117884763(-) A-I      intronic
chr6:117912257(-) A-I      intronic
chr6:117912252(-) A-I      intronic
chr6:117912242(-) A-I      intronic
chr6:117885355(-) A-I      intronic
chr6:117885265(-) A-I      intronic
chr6:117884761(-) A-I      intronic
chr6:117884640(-) A-I      intronic
chr6:117884877(-) A-I      intronic
chr6:117907783(-) A-I      intronic
chr6:117884773(-) A-I      intronic
chr6:117909262(-) A-I      intronic
chr6:117911523(-) A-I      intronic
chr6:117884802(-) A-I      intronic
chr6:117884641(-) A-I      intronic
chr6:117884655(-) A-I      intronic
chr6:117907845(-) A-I      intronic
chr6:117884776(-) A-I      intronic
chr6:117885342(-) A-I      intronic
chr6:117885238(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED GOPC
chr6:117903876(-) A-G intron -    22484847
chr6:117907783(-) A-G intron -    22484847
chr6:117907845(-) A-G intron -    22484847
chr6:117911628(-) T-C intron -    22484847
chr6:117912078(-) A-G intron -    22484847
chr6:117912242(-) A-G intron -    22484847
chr6:117912252(-) A-G intron -    22484847
chr6:117912257(-) A-G intron -    22484847
chr6:117912287(-) A-G intron -    22484847
chr6:117913448(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase GOPC
chr6:117881454-117881455(-) m6A 3'UTR       27773535
chr6:117884125-117884126(-) m6A 3'UTR       27773535
chr6:117884190-117884191(-) m6A 3'UTR       24284625//24209618//27773535
chr6:117884234-117884235(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr6:117884255-117884256(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr6:117884274-117884275(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr6:117884340-117884341(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr6:117884381-117884382(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr6:117884398-117884399(-) m6A 3'UTR       24284625//24209618//24981863//28052920//27773535//22608085
chr6:117884484-117884485(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr6:117884504-117884505(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr6:117888045-117888046(-) m6A CDS       24209618//24981863//27773535
chr6:117888110-117888111(-) m6A CDS       27773535
chr6:117896377-117896378(-) m6A CDS       24981863
chr6:117896416-117896417(-) m6A CDS       24981863
chr6:117896495-117896496(-) m6A CDS       24981863
chr6:117923269-117923270(-) m6A CDS       -
chr6:117923278-117923279(-) m6A CDS       27773535
chr6:117923670-117923671(-) m6A 5'UTR       24981863//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548c-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Urine     -
GOPC
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-548c-5p
Emodin 3220 Drug interaction    RC00007211
Sorafenib 216239 Drug interaction    RC00007212
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-548c-5p
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548c-5p
Interactor2: GOPC

Evidence Support:


Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 33201341 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.

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