Basic Information:

  VIRBase ID:  

HHID00108228

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-590-3p:  MIMAT0004801          MICU3:  NM_001349810     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-590-3p	MICU3
miRBase Accession/Entrez ID	MIMAT0004801	286097
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	EFHA2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-590-3p	rs1435070247 chr7:74191262    G/T rs1554709913 chr7:74191261    T/C rs1554709916 chr7:74191263    T/C rs1554709918 chr7:74191268    G/A rs555659597 chr7:74191273    T/G rs6971711 chr7:74191269    C/T rs781868890 chr7:74191265    T/C rs781868890 chr7:74191265    T/G rs782545428 chr7:74191272    GTC/G rs782782687 chr7:74191264    A/G rs1554709912 chr7:74191255    AT/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MICU3	chr8:16886917(+) A-I      intronic chr8:16931669(+) A-I      intronic chr8:16896230(+) A-I      intronic chr8:16888928(+) A-I      intronic chr8:16889033(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MICU3	chr8:16977807-16977808(+) m6A 3'UTR       24981863 chr8:16977942-16977943(+) m6A 3'UTR       24981863 chr8:16977955-16977956(+) m6A 3'UTR       24981863 chr8:16977962-16977963(+) m6A 3'UTR       24981863 chr8:16978036-16978037(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-590-3p	Exosome Plasma     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	MICU3	Cytosol HCC cell line (HepG2)     - Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-590-3p
Interactor2: MICU3

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.