Basic Information:

  VIRBase ID:  

HHID00108059

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-590-3p:  MIMAT0004801          RAB9A:  NM_001195328     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-590-3p	RAB9A
miRBase Accession/Entrez ID	MIMAT0004801	9367
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	RAB9

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-590-3p	rs1435070247 chr7:74191262    G/T rs1554709913 chr7:74191261    T/C rs1554709916 chr7:74191263    T/C rs1554709918 chr7:74191268    G/A rs555659597 chr7:74191273    T/G rs6971711 chr7:74191269    C/T rs781868890 chr7:74191265    T/C rs781868890 chr7:74191265    T/G rs782545428 chr7:74191272    GTC/G rs782782687 chr7:74191264    A/G rs1554709912 chr7:74191255    AT/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RAB9A	chrX:13718154(+) A-I      intronic chrX:13718185(+) A-I      intronic chrX:13718204(+) A-I      intronic chrX:13718193(+) A-I      intronic chrX:13718197(+) A-I      intronic chrX:13714325(+) A-I      intronic chrX:13714444(+) A-I      intronic chrX:13724550(+) A-I      intronic chrX:13726413(+) A-I      intronic chrX:13726304(+) A-I      intronic chrX:13724727(+) A-I      intronic chrX:13724604(+) A-I      intronic chrX:13709691(+) A-I      intronic chrX:13709614(+) A-I      intronic chrX:13709579(+) A-I      intronic chrX:13709734(+) A-I      intronic chrX:13709699(+) A-I      intronic chrX:13714265(+) A-I      intronic chrX:13709623(+) A-I      intronic chrX:13726296(+) A-I      intronic chrX:13726377(+) A-I      intronic chrX:13709700(+) A-I      intronic chrX:13709658(+) A-I      intronic chrX:13709572(+) A-I      intronic chrX:13709659(+) A-I      intronic chrX:13709711(+) A-I      intronic chrX:13709626(+) A-I      intronic chrX:13709569(+) A-I      intronic chrX:13709627(+) A-I      intronic chrX:13709636(+) A-I      intronic chrX:13709632(+) A-I      intronic chrX:13709731(+) A-I      intronic chrX:13709621(+) A-I      intronic chrX:13719020(+) A-I      intronic chrX:13726387(+) A-I      intronic chrX:13726277(+) A-I      intronic chrX:13726241(+) A-I      intronic chrX:13724591(+) A-I      intronic chrX:13719003(+) A-I      intronic chrX:13726177(+) A-I      intronic chrX:13726255(+) A-I      intronic chrX:13726363(+) A-I      intronic chrX:13718253(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RAB9A	chrX:13709569(+) A-I intron -    22028664 chrX:13709572(+) A-I intron -    22028664 chrX:13709579(+) A-I intron -    22028664 chrX:13709614(+) A-I intron -    22028664 chrX:13709619(+) A-I intron -    22028664 chrX:13709621(+) A-I intron -    22028664 chrX:13709623(+) A-I intron -    22028664 chrX:13709626(+) A-I intron -    22028664 chrX:13709627(+) A-I intron -    22028664 chrX:13709632(+) A-I intron -    22028664 chrX:13709636(+) A-I intron -    22028664 chrX:13709658(+) A-I intron -    22028664 chrX:13709659(+) A-I intron -    22028664 chrX:13709691(+) A-I intron -    22028664 chrX:13709699(+) A-I intron -    22028664 chrX:13709700(+) A-I intron -    22028664 chrX:13709711(+) A-I intron -    22028664 chrX:13709731(+) A-I intron -    22028664 chrX:13709734(+) A-I intron -    22028664 chrX:13726241(+) A-G intron -    22484847 chrX:13726296(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RAB9A	chrX:13721973-13721974(+) m6A 5'UTR//intron       24284625 chrX:13726938-13726939(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chrX:13727023-13727024(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:13727049-13727050(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:13727084-13727085(+) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chrX:13727154-13727155(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chrX:13727295-13727296(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chrX:13727321-13727322(+) m6A CDS//exon       24284625//24981863//27773535//22575960//22608085 chrX:13727417-13727418(+) m6A CDS//exon       24284625//24981863//26404942//27773535//22608085 chrX:13727583-13727584(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chrX:13727620-13727621(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chrX:13727751-13727752(+) m6A 3'UTR       24981863//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-590-3p	Exosome Plasma     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	RAB9A	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-590-3p
Interactor2: RAB9A

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.