Basic Information:

  VIRBase ID:  

HHID00107893

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548b-5p:  MIMAT0004798          MYCN:  NM_001293233     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548b-5p	MYCN
miRBase Accession/Entrez ID	MIMAT0004798	4613
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	bHLHe37//MODED//N-myc//NMYC//ODED

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548b-5p	rs1180266201 chr6:119069102    A/G rs1338611711 chr6:119069100    C/T rs188182113 chr6:119069098    G/A rs188182113 chr6:119069098    G/C rs1158490090 chr6:119069118    T/C rs1414502200 chr6:119069112    T/A rs1472929879 chr6:119069115    C/A

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MYCN	chr2:16080727-16080728(+) m6A 5'UTR       25456834//24981863 chr2:16080774-16080775(+) m6A 5'UTR       25456834//24981863 chr2:16080791-16080792(+) m6A 5'UTR       25456834//24981863 chr2:16080820-16080821(+) m6A 5'UTR       25456834//24981863 chr2:16082232-16082233(+) m6A CDS       25456834 chr2:16082238-16082239(+) m6A CDS       25456834 chr2:16082328-16082329(+) m6A CDS       24209618//25456834//24981863 chr2:16082488-16082489(+) m6A CDS       24209618//25456834//24981863 chr2:16082526-16082527(+) m6A CDS       24209618//25456834//24981863 chr2:16085944-16085945(+) m6A CDS       24209618//25456834//24981863 chr2:16085959-16085960(+) m6A CDS       24209618//25456834//24981863 chr2:16085977-16085978(+) m6A CDS       24209618//25456834//24981863 chr2:16086040-16086041(+) m6A CDS       24284625//24209618//25456834//24981863 chr2:16086173-16086174(+) m6A CDS       24284625//24209618//25456834//24981863//27773535 chr2:16086200-16086201(+) m6A CDS       24284625//24209618//25456834//24981863//27773535 chr2:16086210-16086211(+) m6A CDS       24284625//24209618//25456834//24981863//27773535 chr2:16086231-16086232(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535 chr2:16086236-16086237(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535 chr2:16086276-16086277(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535 chr2:16086358-16086359(+) m6A 3'UTR       24209618//25456834//24981863 chr2:16086383-16086384(+) m6A 3'UTR       25456834//24981863 chr2:16086522-16086523(+) m6A 3'UTR       25456834//24981863//27773535 chr2:16086611-16086612(+) m6A 3'UTR       24981863//27773535 chr2:16086693-16086694(+) m6A 3'UTR       24981863//27773535 chr2:16086913-16086914(+) m6A 3'UTR       27773535 chr2:16086921-16086922(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548b-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	MYCN	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548b-5p
Interactor2: MYCN

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.