Basic Information:

  VIRBase ID:  

HHID00106587

  Virus:  

SARS-CoV-2 (NC_045512.2)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30d-5p:  MIMAT0000245          GOLGA1:  NM_002077     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-30d-5p	GOLGA1
miRBase Accession/Entrez ID	MIMAT0000245	2800
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	golgin-97

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-30d-5p	rs1203910650 chr8:134804928    G/A rs1244539439 chr8:134804930    G/T rs1441595222 chr8:134804927    C/A rs1441595222 chr8:134804927    C/T rs374432132 chr8:134804931    G/A rs776972352 chr8:134804925    G/A rs1187386485 chr8:134804934    G/A rs1373057893 chr8:134804937    TACA/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	GOLGA1	chr9:127672540(-) A-I      intronic chr9:127672545(-) A-I      intronic chr9:127672563(-) A-I      intronic chr9:127674879(-) A-I      intronic chr9:127674914(-) A-I      intronic chr9:127674960(-) A-I      intronic chr9:127675077(-) A-I      intronic chr9:127678059(-) A-I      intronic chr9:127678138(-) A-I      intronic chr9:127678269(-) A-I      intronic chr9:127678298(-) A-I      intronic chr9:127678305(-) A-I      intronic chr9:127680166(-) A-I      intronic chr9:127666135(-) A-I      intronic chr9:127666125(-) A-I      intronic chr9:127680224(-) A-I      intronic chr9:127680228(-) A-I      intronic chr9:127680229(-) A-I      intronic chr9:127680326(-) A-I      intronic chr9:127680328(-) A-I      intronic chr9:127680347(-) A-I      intronic chr9:127680368(-) A-I      intronic chr9:127680377(-) A-I      intronic chr9:127680412(-) A-I      intronic chr9:127680851(-) A-I      intronic chr9:127680949(-) A-I      intronic chr9:127680988(-) A-I      intronic chr9:127681049(-) A-I      intronic chr9:127684596(-) A-I      intronic chr9:127684803(-) A-I      intronic chr9:127686259(-) A-I      intronic chr9:127686402(-) A-I      intronic chr9:127687231(-) A-I      intronic chr9:127687237(-) A-I      intronic chr9:127687247(-) A-I      intronic chr9:127687815(-) A-I      intronic chr9:127697107(-) A-I      intronic chr9:127698962(-) A-I      intronic chr9:127686303(-) A-I      intronic chr9:127686304(-) A-I      intronic chr9:127701970(-) A-I      intronic chr9:127701979(-) A-I      intronic chr9:127701996(-) A-I      intronic chr9:127702014(-) A-I      intronic chr9:127702018(-) A-I      intronic chr9:127702020(-) A-I      intronic chr9:127702023(-) A-I      intronic chr9:127659049(-) A-I      intronic chr9:127666247(-) A-I      intronic chr9:127666242(-) A-I      intronic chr9:127664963(-) A-I      intronic chr9:127664946(-) A-I      intronic chr9:127664943(-) A-I      intronic chr9:127663586(-) A-I      intronic chr9:127663389(-) A-I      intronic chr9:127663343(-) A-I      intronic chr9:127659159(-) A-I      intronic chr9:127659143(-) A-I      intronic chr9:127659142(-) A-I      intronic chr9:127659125(-) A-I      intronic chr9:127659095(-) A-I      intronic chr9:127656768(-) A-I      intronic chr9:127655128(-) A-I      intronic chr9:127654453(-) A-I      intronic chr9:127654371(-) A-I      intronic chr9:127654362(-) A-I      intronic chr9:127647457(-) A-I      intronic chr9:127647364(-) A-I      intronic chr9:127646383(-) A-I      intronic chr9:127645891(-) A-I      intronic chr9:127645871(-) A-I      intronic chr9:127645868(-) A-I      intronic chr9:127645855(-) A-I      intronic chr9:127645703(-) A-I      intronic chr9:127645637(-) A-I      intronic chr9:127645625(-) A-I      intronic chr9:127645599(-) A-I      intronic chr9:127666255(-) A-I      intronic chr9:127671414(-) A-I      intronic chr9:127671470(-) A-I      intronic chr9:127671577(-) A-I      intronic chr9:127671719(-) A-I      intronic chr9:127671804(-) A-I      intronic chr9:127671805(-) A-I      intronic chr9:127672181(-) A-I      intronic chr9:127672277(-) A-I      intronic chr9:127672348(-) A-I      intronic chr9:127672385(-) A-I      intronic chr9:127672483(-) A-I      intronic chr9:127646470(-) A-I      intronic chr9:127655001(-) A-I      intronic chr9:127686299(-) A-I      intronic chr9:127699002(-) A-I      intronic chr9:127674986(-) A-I      intronic chr9:127659760(-) A-I      intronic chr9:127646469(-) A-I      intronic chr9:127647311(-) A-I      intronic chr9:127672168(-) A-I      intronic chr9:127659757(-) A-I      intronic chr9:127695791(-) A-I      intronic chr9:127680825(-) A-I      intronic chr9:127687914(-) A-I      intronic chr9:127682634(-) A-I      intronic chr9:127671354(-) A-I      intronic chr9:127681271(-) A-I      intronic chr9:127681306(-) A-I      intronic chr9:127645816(-) A-I      intronic chr9:127675005(-) A-I      intronic chr9:127647308(-) A-I      intronic chr9:127659135(-) A-I      intronic chr9:127672158(-) A-I      intronic chr9:127682376(-) A-I      intronic chr9:127659692(-) A-I      intronic chr9:127682497(-) A-I      intronic chr9:127646563(-) A-I      intronic chr9:127687831(-) A-I      intronic chr9:127698981(-) A-I      intronic chr9:127655046(-) A-I      intronic chr9:127646564(-) A-I      intronic chr9:127695966(-) A-I      intronic chr9:127698788(-) A-I      intronic chr9:127647663(-) A-I      intronic chr9:127682368(-) A-I      intronic chr9:127665522(-) A-I      intronic chr9:127666266(-) A-I      intronic chr9:127659686(-) A-I      intronic chr9:127686186(-) A-I      intronic chr9:127655309(-) A-I      intronic chr9:127658964(-) A-I      intronic chr9:127681460(-) A-I      intronic chr9:127647682(-) A-I      intronic chr9:127686267(-) A-I      intronic chr9:127647504(-) A-I      intronic chr9:127654955(-) A-I      intronic chr9:127682651(-) A-I      intronic chr9:127697274(-) A-I      intronic chr9:127675024(-) A-I      intronic chr9:127647233(-) A-I      intronic chr9:127682667(-) A-I      intronic chr9:127659784(-) A-I      intronic chr9:127665658(-) A-I      intronic chr9:127658606(-) A-I      intronic chr9:127645451(-) A-I      intronic chr9:127682629(-) A-I      intronic chr9:127686232(-) A-I      intronic chr9:127686914(-) A-I      intronic chr9:127675094(-) A-I      intronic chr9:127682563(-) A-I      intronic chr9:127680959(-) A-I      intronic chr9:127647642(-) A-I      intronic chr9:127645904(-) A-I      intronic chr9:127687941(-) A-I      intronic chr9:127664663(-) A-I      intronic chr9:127680301(-) A-I      intronic chr9:127654483(-) A-I      intronic chr9:127697060(-) A-I      intronic chr9:127666179(-) A-I      intronic chr9:127666295(-) A-I      intronic chr9:127680204(-) A-I      intronic chr9:127681293(-) A-I      intronic chr9:127675093(-) A-I      intronic chr9:127671491(-) A-I      intronic chr9:127682559(-) A-I      intronic chr9:127647652(-) A-I      intronic chr9:127646321(-) A-I      intronic chr9:127686207(-) A-I      intronic chr9:127646358(-) A-I      intronic chr9:127681412(-) A-I      intronic chr9:127658571(-) A-I      intronic chr9:127654457(-) A-I      intronic chr9:127646376(-) A-I      intronic chr9:127681414(-) A-I      intronic chr9:127654388(-) A-I      intronic chr9:127659799(-) A-I      intronic chr9:127682377(-) A-I      intronic chr9:127682566(-) A-I      intronic chr9:127664664(-) A-I      intronic chr9:127659003(-) A-I      intronic chr9:127645544(-) A-I      intronic chr9:127681441(-) A-I      intronic chr9:127647351(-) A-I      intronic chr9:127666165(-) A-I      intronic chr9:127686255(-) A-I      intronic chr9:127647232(-) A-I      intronic chr9:127699810(-) A-I      intronic chr9:127645702(-) A-I      intronic chr9:127663375(-) A-I      intronic chr9:127654203(-) A-I      intronic chr9:127659720(-) A-I      intronic chr9:127647523(-) A-I      intronic chr9:127645864(-) A-I      intronic chr9:127658976(-) A-I      intronic chr9:127666180(-) A-I      intronic chr9:127647655(-) A-I      intronic chr9:127645819(-) A-I      intronic chr9:127686685(-) A-I      intronic chr9:127659128(-) A-I      intronic chr9:127656699(-) A-I      intronic chr9:127663889(-) A-I      intronic chr9:127659099(-) A-I      intronic chr9:127686717(-) A-I      intronic chr9:127681310(-) A-I      intronic chr9:127666170(-) A-I      intronic chr9:127654204(-) A-I      intronic chr9:127698866(-) A-I      intronic chr9:127647664(-) A-I      intronic chr9:127646541(-) A-I      intronic chr9:127686273(-) A-I      intronic chr9:127659053(-) A-I      intronic chr9:127666316(-) A-I      intronic chr9:127680404(-) A-I      intronic chr9:127646468(-) A-I      intronic chr9:127647681(-) A-I      intronic chr9:127680270(-) A-I      intronic chr9:127645768(-) A-I      intronic chr9:127664565(-) A-I      intronic chr9:127647762(-) A-I      intronic chr9:127698841(-) A-I      intronic chr9:127686231(-) A-I      intronic chr9:127678132(-) A-I      intronic chr9:127685688(-) A-I      intronic chr9:127659124(-) A-I      intronic chr9:127685683(-) A-I      intronic chr9:127655371(-) A-I      intronic chr9:127647220(-) A-I      intronic chr9:127653313(-) A-I      intronic chr9:127699003(-) A-I      intronic chr9:127684944(-) A-I      intronic chr9:127653323(-) A-I      intronic chr9:127697264(-) A-I      intronic chr9:127663430(-) A-I      intronic chr9:127681532(-) A-I      intronic chr9:127687739(-) A-I      intronic chr9:127687832(-) A-I      intronic chr9:127658666(-) A-I      intronic chr9:127659878(-) A-I      intronic chr9:127654990(-) A-I      intronic chr9:127665541(-) A-I      intronic chr9:127687745(-) A-I      intronic chr9:127659102(-) A-I      intronic chr9:127645920(-) A-I      intronic chr9:127665521(-) A-I      intronic chr9:127663425(-) A-I      intronic chr9:127680940(-) A-I      intronic chr9:127686787(-) A-I      intronic chr9:127646533(-) A-I      intronic chr9:127647640(-) A-I      intronic chr9:127681345(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	GOLGA1	chr9:127647861(-) C-T intron -    22484847 chr9:127645819(-) A-G intron -    22484847 chr9:127645864(-) A-G intron -    22484847 chr9:127654457(-) A-G intron -    22484847 chr9:127659686(-) A-G intron -    22484847 chr9:127659692(-) A-G intron -    22484847 chr9:127659760(-) A-G intron -    22484847 chr9:127663375(-) A-G intron -    22484847 chr9:127663430(-) A-G intron -    22484847 chr9:127665521(-) A-G intron -    22484847 chr9:127665541(-) A-G intron -    22484847 chr9:127665584(-) A-G intron -    22484847 chr9:127680301(-) A-G intron -    22484847 chr9:127686208(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GOLGA1	chr9:127641497-127641498(-) m6A 3'UTR       27773535 chr9:127641539-127641540(-) m6A 3'UTR       27773535 chr9:127641583-127641584(-) m6A 3'UTR       27773535 chr9:127641621-127641622(-) m6A 3'UTR       27773535 chr9:127641766-127641767(-) m6A 3'UTR       27773535 chr9:127642071-127642072(-) m6A 3'UTR       27773535 chr9:127642081-127642082(-) m6A 3'UTR       27773535 chr9:127642150-127642151(-) m6A 3'UTR       27773535 chr9:127642170-127642171(-) m6A 3'UTR       27773535 chr9:127642255-127642256(-) m6A 3'UTR       24284625//24981863//27773535 chr9:127642265-127642266(-) m6A 3'UTR       24284625//24981863//27773535 chr9:127642356-127642357(-) m6A 3'UTR       27773535//27371828 chr9:127642374-127642375(-) m6A 3'UTR       27773535//27371828 chr9:127642395-127642396(-) m6A 3'UTR       27773535//27371828 chr9:127642753-127642754(-) m6A 3'UTR       24981863 chr9:127642802-127642803(-) m6A 3'UTR       24981863 chr9:127650562-127650563(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127650567-127650568(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127650620-127650621(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127650652-127650653(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127651479-127651480(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127651522-127651523(-) m6A 3'UTR//CDS       27371828//27773536 chr9:127651760-127651761(-) m6A 3'UTR//CDS       24981863//27773535//27371828 chr9:127651779-127651780(-) m6A 3'UTR//CDS       24981863//27773535//27371828 chr9:127660842-127660843(-) m6A 3'UTR//CDS       24209618//24981863//27773535//27371828 chr9:127660920-127660921(-) m6A 3'UTR//CDS       24209618//27773535//27371828 chr9:127661627-127661628(-) m6A 3'UTR//CDS       24209618//27773535//27371828 chr9:127662807-127662808(-) m6A 3'UTR//CDS//exon       27773535 chr9:127662817-127662818(-) m6A 3'UTR//CDS//exon       27773535 chr9:127670660-127670661(-) m6A 3'UTR//CDS//exon       27773535 chr9:127670715-127670716(-) m6A 3'UTR//CDS//exon       27773535 chr9:127670747-127670748(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr9:127674191-127674192(-) m6A 3'UTR//CDS//exon       24981863//27773535 chr9:127674203-127674204(-) m6A 3'UTR//CDS       24981863//27773535 chr9:127674219-127674220(-) m6A 3'UTR//CDS       27773535 chr9:127674224-127674225(-) m6A 3'UTR//CDS       27773535 chr9:127674230-127674231(-) m6A 3'UTR//CDS       27773535 chr9:127674292-127674293(-) m6A 3'UTR//CDS       24981863//27773535 chr9:127683455-127683456(-) m6A CDS//intron       24981863 chr9:127683464-127683465(-) m6A CDS//intron       24981863 chr9:127683496-127683497(-) m6A CDS//intron       24981863 chr9:127684027-127684028(-) m6A CDS       24981863//27773535 chr9:127684058-127684059(-) m6A CDS       24981863//27773535 chr9:127684079-127684080(-) m6A CDS       24981863//27773535 chr9:127684108-127684109(-) m6A CDS       24981863//27773535 chr9:127684116-127684117(-) m6A CDS       24981863//27773535 chr9:127684135-127684136(-) m6A CDS       24981863//27773535 chr9:127685394-127685395(-) m6A CDS       27773535 chr9:127685461-127685462(-) m6A CDS       27773535 chr9:127690470-127690471(-) m6A CDS       27773535 chr9:127690496-127690497(-) m6A CDS       27773535 chr9:127690531-127690532(-) m6A CDS       24981863//27773535 chr9:127691504-127691505(-) m6A CDS       24981863 chr9:127705398-127705399(-) m6A intron       - chr9:127708250-127708251(-) m6A intron       27773535 chr9:127708338-127708339(-) m6A intron       27773535 chr9:127710154-127710155(-) m6A exon//intron       24981863 chr9:127710212-127710213(-) m6A 5'UTR//exon       24981863 chr9:127710221-127710222(-) m6A 5'UTR//exon       24981863 chr9:127710248-127710249(-) m6A 5'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-30d-5p	Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome HCC tissues     30542726 Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Renal cancer cells     21670082 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Cerebrospinal fluid     25420022 Exosome Blood|B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Colon tissue|Endothelial cells|Epithelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Seminal fluid|Tongue tissue     - Extracellular vesicle HEK-293T cells     22849433 Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Follicular fluid     23666971 Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleolus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
	GOLGA1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-30d-5p	Midostaurin 9829523 Drug resistant Herveline O 5459269 Drug sensitive Cuspidatin C 5459164 Drug sensitive 2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant Antimycin A3 245869 Drug sensitive 5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive 4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive Kinetin riboside 20345 Drug resistant Astrazon Orange R 135747272 Drug sensitive Cladospirone bisepoxide 10316810 Drug sensitive (3Z,4R)-4-Hydroxy-3-[2-[(1S,3R)-3-[2-[(1S,3S,3'R,4S)-1-hydroxy-4,6,6-trimethylspiro[2,5-dioxabicyclo[2.2.2]octane-3,6'-oxane]-3'-yl]ethyl]-2,2-dimethyl-6-methylidenecyclohexyl]ethylidene]oxolan-2-one 101206903 Drug sensitive antineoplastic-d655481 - Drug resistant 4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive 4-morpholinecarbodithioic acid, antimony complex - Drug sensitive 7-n,n-dimethylamino brefeldin a hydrochloride - Drug sensitive E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive isatin dr - Drug sensitive tetra(isobutenyl)antimony bromide - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-30d-5p	Gemcitabine 60750 Drug interaction    RC00001621 Sunitinib 5329102 Drug interaction    RC00001626 Eloxatine 5310940 Drug interaction    RC00001625 Trichostatin A 444732 Drug interaction    RC00001624 Paroxetine 43815 Drug interaction    RC00001620 Etoposide 36462 Drug interaction    RC00001619 5-Fluorouracil 3385 Drug interaction    RC00001617 Doxorubicin 31703 Drug interaction    RC00001618 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00001616 Verapamil 2520 Drug interaction    RC00001615 N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00001627 Bicalutamide 2375 Drug interaction    RC00001614 Docetaxel 148124 Drug interaction    RC00001623 1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00001628 Trastuzumab - Drug interaction    RC00001629

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-30d-5p	N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-30d-5p
Interactor2: GOLGA1

Evidence Support:

Prediction-Evidence	miRDB
Support Database	ViRBase

References:

PMID	33201341	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	By custom target prediction, a panel of miRNA sequences able to recognize the SARS-CoV-2 sequence was collected. Only targets with a very high score (95-100) were retained for further analyses.