Detail Information

Basic Information:


  VIRBase ID:  

HHID00105398

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-212-5p:           ACE2:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-212-5p ACE2
miRBase
Accession/Entrez ID		 MIMAT0022695 59272
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ACEH

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-212-5p
rs1277656847 chr17:2050329    G/T
rs1291872641 chr17:2050342    A/G
rs1356091112 chr17:2050336    G/C
rs1397410801 chr17:2050328    A/G
rs1462415672 chr17:2050334    C/T
rs533755402 chr17:2050341    G/A
rs533755402 chr17:2050341    G/C
rs774549341 chr17:2050337    T/A
rs774549341 chr17:2050337    T/G
rs935188346 chr17:2050333    G/C
rs1044782167 chr17:2050348    G/A
rs547555046 chr17:2050343    G/A
rs775995138 chr17:2050344    C/A
rs775995138 chr17:2050344    C/G

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ACE2
chrX:15579319-15579320(-) m6A 3'UTR//exon       27773535
chrX:15579343-15579344(-) m6A 3'UTR//exon       27773535
chrX:15579366-15579367(-) m6A 3'UTR//exon       27773535
chrX:15579420-15579421(-) m6A 3'UTR//exon       27773535
chrX:15579431-15579432(-) m6A 3'UTR//intron       27773535
chrX:15579618-15579619(-) m6A 3'UTR//intron       27773535
chrX:15579631-15579632(-) m6A 3'UTR//intron       27773535
chrX:15579696-15579697(-) m6A 3'UTR//exon       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-212-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
ACE2
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-212-5p
Interactor2: ACE2

Evidence Support:


Prediction-Evidence microT//miRanda//miRMap//PicTar//PITA//Targetscan
Support Database ViRBase

References:


PMID 33428154 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description To explore the regulatory relationship between the 5 key genes, 3 coronavirus-related genes (ACE2, TMPRSS2, BSG), and their target miRNA, we used 6 miRNA target prediction databases to predict the target miRNA of these genes.

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