Detail Information

Basic Information:


  VIRBase ID:  

HHID00105378

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3187-3p:           TLR7:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3187-3p TLR7
miRBase
Accession/Entrez ID		 MIMAT0015069 51284
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IMD74//TLR7-like

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3187-3p
rs1025138110 chr19:813643    G/A
rs1359317584 chr19:813638    G/A
rs1397804140 chr19:813642    C/T
rs769339066 chr19:813644    C/T
rs774945981 chr19:813645    G/A
rs867126287 chr19:813640    T/G
rs868127809 chr19:813636    G/T
rs912544725 chr19:813646    G/A
rs1028153194 chr19:813630    G/C
rs1173834237 chr19:813628    T/C
rs992822940 chr19:813632    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TLR7
chrX:12894099(+) A-I      intronic
chrX:12892292(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TLR7
chrX:12895719-12895720(+) m6A exon//intron       -
chrX:12903645-12903646(+) m6A CDS       -
chrX:12903656-12903657(+) m6A CDS       -
chrX:12903695-12903696(+) m6A CDS       -
chrX:12903723-12903724(+) m6A CDS       -
chrX:12903760-12903761(+) m6A CDS       -
chrX:12903775-12903776(+) m6A CDS       -
chrX:12903784-12903785(+) m6A CDS       -
chrX:12903823-12903824(+) m6A CDS       -
chrX:12903832-12903833(+) m6A CDS       -
chrX:12903862-12903863(+) m6A CDS       -
chrX:12903887-12903888(+) m6A CDS       -
chrX:12903892-12903893(+) m6A CDS       -
chrX:12903952-12903953(+) m6A CDS       -
chrX:12903983-12903984(+) m6A CDS       -
chrX:12904001-12904002(+) m6A CDS       -
chrX:12904036-12904037(+) m6A CDS       -
chrX:12904136-12904137(+) m6A CDS       -
chrX:12904171-12904172(+) m6A CDS       -
chrX:12904231-12904232(+) m6A CDS       -
chrX:12904313-12904314(+) m6A CDS       -
chrX:12904561-12904562(+) m6A CDS       -
chrX:12904571-12904572(+) m6A CDS       -
chrX:12904580-12904581(+) m6A CDS       -
chrX:12904597-12904598(+) m6A CDS       -
chrX:12904682-12904683(+) m6A CDS       -
chrX:12904880-12904881(+) m6A CDS       -
chrX:12904892-12904893(+) m6A CDS       -
chrX:12904974-12904975(+) m6A CDS       -
chrX:12904994-12904995(+) m6A CDS       -
chrX:12905009-12905010(+) m6A CDS       -
chrX:12905062-12905063(+) m6A CDS       -
chrX:12905115-12905116(+) m6A CDS       -
chrX:12905220-12905221(+) m6A CDS       -
chrX:12905269-12905270(+) m6A CDS       -
chrX:12905327-12905328(+) m6A CDS       -
chrX:12905395-12905396(+) m6A CDS       -
chrX:12905407-12905408(+) m6A CDS       -
chrX:12905426-12905427(+) m6A CDS       -
chrX:12905469-12905470(+) m6A CDS       -
chrX:12905493-12905494(+) m6A CDS       -
chrX:12905593-12905594(+) m6A CDS       -
chrX:12905708-12905709(+) m6A CDS       -
chrX:12905725-12905726(+) m6A CDS       -
chrX:12905733-12905734(+) m6A CDS       -
chrX:12905740-12905741(+) m6A CDS       -
chrX:12905919-12905920(+) m6A CDS       -
chrX:12906289-12906290(+) m6A CDS       -
chrX:12906328-12906329(+) m6A CDS       -
chrX:12906371-12906372(+) m6A CDS       -
chrX:12906379-12906380(+) m6A CDS       -
chrX:12906392-12906393(+) m6A CDS       -
chrX:12906421-12906422(+) m6A CDS       -
chrX:12906451-12906452(+) m6A CDS       -
chrX:12906483-12906484(+) m6A CDS       -
chrX:12906502-12906503(+) m6A CDS       -
chrX:12906516-12906517(+) m6A CDS       -
chrX:12907879-12907880(+) m6A 3'UTR       -
chrX:12907958-12907959(+) m6A 3'UTR       -
chrX:12907971-12907972(+) m6A 3'UTR       -
chrX:12908075-12908076(+) m6A 3'UTR       -
chrX:12908089-12908090(+) m6A 3'UTR       -
chrX:12908119-12908120(+) m6A 3'UTR       -
chrX:12908141-12908142(+) m6A 3'UTR       -
chrX:12908153-12908154(+) m6A 3'UTR       -
chrX:12908159-12908160(+) m6A 3'UTR       -
chrX:12908218-12908219(+) m6A 3'UTR       -
chrX:12908283-12908284(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3187-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
TLR7
Exosome Blood     -
Nucleoplasm K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-3187-3p
Gemcitabine 60750 Drug interaction    RC00008135
5-Fluorouracil 3385 Drug interaction    RC00008134
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00008136
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-3187-3p
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3187-3p
Interactor2: TLR7

Evidence Support:


Prediction-Evidence microT//miRanda//miRMap//PicTar//PITA//Targetscan
Support Database ViRBase

References:


PMID 33428154 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description To explore the regulatory relationship between the 5 key genes, 3 coronavirus-related genes (ACE2, TMPRSS2, BSG), and their target miRNA, we used 6 miRNA target prediction databases to predict the target miRNA of these genes.

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