Detail Information

Basic Information:


  VIRBase ID:  

HHID00105355

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1286:           BSG:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1286 BSG
miRBase
Accession/Entrez ID
MIMAT0005877 682
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - 5F7//CD147//EMMPRIN//EMPRIN//HAb18G//OK//SLC7A11//TCSF

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1286
rs1172464414 chr22:20249150    T/A
rs1172464414 chr22:20249150    T/C
rs1412182081 chr22:20249157    G/C
rs1454986719 chr22:20249147    G/C
rs376167250 chr22:20249154    C/T
rs1394684969 chr22:20249162    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BSG
chr19:572192(+) A-I      intronic
chr19:574162(+) A-I      intronic
chr19:576506(+) A-I      intronic
chr19:576564(+) A-I      intronic
chr19:576595(+) A-I      intronic
chr19:576598(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED BSG
chr19:583488(+) C-A intron -    21725310

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BSG
chr19:571454-571455(+) m6A 5'UTR       24981863
chr19:571517-571518(+) m6A 5'UTR       24981863
chr19:572614-572615(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863//26404942//22575960
chr19:575063-575064(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863//26404942//22575960
chr19:575233-575234(+) m6A 5'UTR//intron       24284625
chr19:579526-579527(+) m6A 5'UTR//CDS//exon//intron       24284625//26404942//22575960
chr19:579735-579736(+) m6A exon//intron       24284625
chr19:579742-579743(+) m6A exon//intron       24284625
chr19:580383-580384(+) m6A 5'UTR//CDS//exon//intron       24284625//22575960
chr19:580570-580571(+) m6A exon//intron       24284625
chr19:580679-580680(+) m6A CDS//exon//intron       24284625//26404942
chr19:580758-580759(+) Am CDS//exon//intron       -
chr19:580777-580778(+) m6A CDS//exon//intron       24284625//26404942//22575960
chr19:581387-581388(+) m6A CDS//exon//intron       24284625//26404942//22575960
chr19:581393-581394(+) m6A CDS//exon//intron       24284625//26404942//22575960
chr19:582566-582567(+) m6A 3'UTR//CDS//exon       24284625//26404942//22575960
chr19:582843-582844(+) m6A 3'UTR//exon       24284625//26404942
chr19:583238-583239(+) m6A 3'UTR//exon       24284625//25456834//24981863//26404942//27773535//22575960
chr19:583345-583346(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22575960
chr19:583363-583364(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22575960
chr19:583371-583372(+) m6A 3'UTR//exon       24284625//25456834//27773535//22575960
chr19:583441-583442(+) m6A 3'UTR//exon       24284625//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1286
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
BSG
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID
Function Link  
RNAInter hsa-miR-1286
5-Fluorouracil 3385 Drug interaction    RC00007717
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-1286

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1286
Interactor2: BSG

Evidence Support:


Prediction-Evidence microT//miRanda//miRMap//PicTar//PITA//Targetscan
Support Database ViRBase

References:


PMID 33428154 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description To explore the regulatory relationship between the 5 key genes, 3 coronavirus-related genes (ACE2, TMPRSS2, BSG), and their target miRNA, we used 6 miRNA target prediction databases to predict the target miRNA of these genes.

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