Basic Information:

  VIRBase ID:  

HHID00105311

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-219a-2-3p:  MIMAT0004675          CXCL10:  NR_168520     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-219a-2-3p	CXCL10
miRBase Accession/Entrez ID	MIMAT0004675	3627
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C7//crg-2//gIP-10//IFI10//INP10//IP-10//mob-1//SCYB10

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-219a-2-3p	rs1175245623 chr9:128392644    C/T rs1413901803 chr9:128392633    C/T rs1357308967 chr9:128392646    A/G

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CXCL10	chr4:76942319-76942320(-) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-219a-2-3p	Exosome Blood     - Microvesicle Blood|Urine     -
	CXCL10	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-219a-2-3p
Interactor2: CXCL10

Evidence Support:

Prediction-Evidence	microT//miRanda//miRMap//PicTar//PITA//Targetscan
Support Database	ViRBase

References:

PMID	33428154	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	To explore the regulatory relationship between the 5 key genes, 3 coronavirus-related genes (ACE2, TMPRSS2, BSG), and their target miRNA, we used 6 miRNA target prediction databases to predict the target miRNA of these genes.