Detail Information

Basic Information:


  VIRBase ID:  

HHID00105263

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.9612

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-502-5p:           DHODH:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-502-5p DHODH
miRBase
Accession/Entrez ID		 MIMAT0002873 1723
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DHOdehase//POADS//URA1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-502-5p
rs1557183210 chrX:50014624    C/G
rs1557183213 chrX:50014627    G/A
rs1557183214 chrX:50014629    T/C
rs1557183215 chrX:50014631    C/A
rs373544813 chrX:50014622    A/G
rs782505645 chrX:50014626    G/T
rs1557183206 chrX:50014617    T/C
rs1557183207 chrX:50014620    C/A
rs1557183207 chrX:50014620    C/G
rs782685418 chrX:50014616    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR DHODH
chr16:72058675(+) A-I      3'UTR
chr16:72053020(+) A-I      intronic
chr16:72058716(+) A-I      3'UTR
chr16:72058737(+) A-I      3'UTR
chr16:72058725(+) A-I      3'UTR
chr16:72058705(+) A-I      3'UTR
chr16:72058689(+) A-I      3'UTR
chr16:72051562(+) A-I      intronic
chr16:72058652(+) A-I      3'UTR
chr16:72058850(+) A-I      3'UTR
chr16:72058691(+) A-I      3'UTR
chr16:72058690(+) A-I      3'UTR
chr16:72058647(+) A-I      3'UTR
chr16:72058741(+) A-I      3'UTR
chr16:72058620(+) A-I      3'UTR
chr16:72055845(+) A-I      intronic
chr16:72055871(+) A-I      intronic
chr16:72053107(+) A-I      intronic
chr16:72054388(+) A-I      intronic
chr16:72053808(+) A-I      intronic
chr16:72055841(+) A-I      intronic
chr16:72053922(+) A-I      intronic
chr16:72058717(+) A-I      3'UTR
chr16:72045336(+) A-I      intronic
chr16:72054440(+) A-I      intronic
chr16:72051860(+) A-I      intronic
chr16:72054064(+) A-I      intronic
chr16:72043882(+) A-I      intronic
chr16:72044899(+) A-I      intronic
chr16:72045309(+) A-I      intronic
chr16:72052984(+) A-I      intronic
chr16:72054512(+) A-I      intronic
chr16:72053813(+) A-I      intronic
chr16:72052972(+) A-I      intronic
chr16:72051880(+) A-I      intronic
chr16:72054013(+) A-I      intronic
chr16:72054157(+) A-I      intronic
chr16:72054068(+) A-I      intronic
chr16:72054100(+) A-I      intronic
chr16:72045399(+) A-I      intronic
chr16:72054087(+) A-I      intronic
chr16:72054486(+) A-I      intronic
chr16:72052955(+) A-I      intronic
chr16:72053777(+) A-I      intronic
chr16:72053786(+) A-I      intronic
chr16:72055698(+) A-I      intronic
chr16:72052924(+) A-I      intronic
chr16:72052934(+) A-I      intronic
chr16:72055956(+) A-I      intronic
chr16:72054331(+) A-I      intronic
chr16:72054055(+) A-I      intronic
chr16:72043899(+) A-I      intronic
chr16:72058721(+) A-I      3'UTR
chr16:72058757(+) A-I      3'UTR
chr16:72058709(+) A-I      3'UTR
chr16:72058748(+) A-I      3'UTR
chr16:72058753(+) A-I      3'UTR
chr16:72058856(+) A-I      3'UTR
chr16:72058711(+) A-I      3'UTR
chr16:72058612(+) A-I      3'UTR
chr16:72058715(+) A-I      3'UTR
chr16:72058714(+) A-I      3'UTR
chr16:72058611(+) A-I      3'UTR
chr16:72058780(+) A-I      3'UTR
chr16:72058818(+) A-I      3'UTR
chr16:72058702(+) A-I      3'UTR
chr16:72058817(+) A-I      3'UTR
chr16:72058747(+) A-I      3'UTR
chr16:72058774(+) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED DHODH
chr16:72052933(+) A-I intron -    22327324
chr16:72058817(+) A-I intron -    22327324
chr16:72051567(+) T-C intron -    22484847
chr16:72052933(+) T-C intron -    22484847
chr16:72053790(+) T-C intron -    22484847
chr16:72053808(+) A-G intron -    22484847
chr16:72054055(+) A-G intron -    22484847
chr16:72054064(+) A-G intron -    22484847
chr16:72054068(+) A-G intron -    22484847
chr16:72054393(+) T-C intron -    22484847
chr16:72054399(+) T-C intron -    22484847
chr16:72054440(+) A-G intron -    22484847
chr16:72055870(+) T-C intron -    22484847
chr16:72058611(+) A-G intron -    22484847
chr16:72058711(+) A-G intron -    22484847
chr16:72058748(+) A-G intron -    22484847
chr16:72058817(+) A-G intron -    22484847
chr16:72058818(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DHODH
chr16:72042634-72042635(+) m6A 5'UTR       24981863
chr16:72042674-72042675(+) m6A CDS       24981863
chr16:72042717-72042718(+) m6A 5'UTR//intron       24981863
chr16:72042724-72042725(+) m6A 5'UTR//intron       24981863
chr16:72042768-72042769(+) m6A 5'UTR//intron       24981863
chr16:72043014-72043015(+) m6A 5'UTR//intron       25456834//24981863
chr16:72043025-72043026(+) m6A 5'UTR//intron       25456834//24981863
chr16:72045989-72045990(+) m6A 5'UTR//CDS       25456834//24981863
chr16:72046043-72046044(+) m6A CDS       25456834
chr16:72046075-72046076(+) m6A CDS       -
chr16:72048454-72048455(+) m6A 3'UTR//CDS//exon       24981863
chr16:72048505-72048506(+) m6A 3'UTR//CDS//exon       24981863
chr16:72049772-72049773(+) m6A exon//intron       27773535
chr16:72050541-72050542(+) m6A exon//intron       27773535
chr16:72050958-72050959(+) m6A 3'UTR//CDS//exon       24981863
chr16:72050976-72050977(+) m6A 3'UTR//CDS//exon       24981863
chr16:72056351-72056352(+) m6A CDS//intron       24284625
chr16:72057091-72057092(+) m6A CDS//exon//intron       24284625
chr16:72057514-72057515(+) m6A CDS//exon//intron       24284625//24209618//22608085
chr16:72058100-72058101(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr16:72058129-72058130(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr16:72058141-72058142(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085
chr16:72058180-72058181(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr16:72058285-72058286(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:72058292-72058293(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:72058299-72058300(+) Y 3'UTR//exon       26075521
chr16:72058321-72058322(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr16:72058348-72058349(+) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr16:72058398-72058399(+) m6A 3'UTR//exon       24284625//24981863//22608085
chr16:72058504-72058505(+) m6A 3'UTR       24981863
chr16:72058554-72058555(+) m6A 3'UTR       24981863
chr16:72058577-72058578(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-502-5p
Cytoplasm GC cell lines (MKN-28|MKN-45)     30953514
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Primary dendritic cells|T cell line (J77)     21505438
Exosome Brain tissue     23382797
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
DHODH
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-502-5p
Tetrangulol 99188 Drug sensitive
Midostaurin 9829523 Drug resistant
(7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione 98137101 Drug resistant
1-(4-Methoxyphenyl)-3-[(2-oxo-3-indolyl)amino]thiourea 947057 Drug resistant
Pentamidine isethionate 8813 Drug sensitive
Acridine Yellow G 8672 Drug resistant
Benzethonium chloride 8478 Drug sensitive
2,4,6-Tris(2-pyridyl)-s-triazine 77258 Drug sensitive
Clothixamide maleate 76972759 Drug sensitive
Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive
Secalonic acid D 73431 Drug sensitive
o-Aminoazotoluene 7340 Drug resistant
5-Methyl-1,10-phenanthroline 72791 Drug resistant
Berberine iodide 72350 Drug sensitive
Coptisine chloride 72321 Drug sensitive
7-Hydroxystaurosporine 72271 Drug resistant
Lauryl isoquinolinium bromide 7132 Drug sensitive
Anaxirone 71218 Drug resistant
Thiocoraline 70698112 Drug resistant
Resorufin 69462 Drug sensitive
1-(2-Pyridylazo)-2-naphthol 6825 Drug resistant
Sulbentine 67686 Drug sensitive
Laurolinium acetate 67354 Drug sensitive
3-Hydroxy-3'-nitro-2-naphthanilide 67277 Drug sensitive
Tacacoside A2 6712615 Drug sensitive
Indazole analogue 17 6539599 Drug sensitive
Tanespimycin 6505803 Drug sensitive
Mevastatin 64715 Drug resistant
Everolimus 6442177 Drug resistant
Verrucarin A 6326658 Drug sensitive
Methylene blue 6099 Drug sensitive
Verrucarin A, 3'-(acetyloxy)-7'-deoxo-2'-deoxy-4'-hydroxy-7'-(1-hydroxyethyl)- 5933240 Drug sensitive
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-(1H-pyrrol-2-yl)thieno[3,2-d]pyrimidin-4-amine;hydrochloride 57401575 Drug resistant
1,1'-Diethyl-2,2'-cyanine chloride 5717105 Drug sensitive
8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive
Iejimalide A. 5473233 Drug sensitive
11-Cyanomethylen-11H-indolo[1,2-a]indazole 5472501 Drug resistant
Antineoplastic-643001 5466797 Drug sensitive
6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug sensitive
Bleomycin 5460769 Drug resistant
Herveline O 5459269 Drug sensitive
Thiram 5455 Drug sensitive
Berberal 5351462 Drug sensitive
1-Piperidineethanol, alpha-[p-(p-chlorostyryl)phenyl]- 5351150 Drug sensitive
5-[2-(4-Hydroxy-2,6-dimethylphenyl)ethenyl]pyridine-3-carboxamide 53239975 Drug sensitive
Proscillaridin 5284613 Drug resistant
Purapuridine 5250 Drug resistant
5-Fluoro-2'-deoxycytidine 515328 Drug resistant
Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498558 Drug sensitive
Staurosporine, 98% 49831000 Drug resistant
6-Bromosangivamycin 470030 Drug resistant
9-beta-D-Xylofuranosyladenine 447916 Drug resistant
Latrunculin a 445420 Drug resistant
4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine 44397453 Drug resistant
1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive
Triciribine phosphate 43860 Drug resistant
Antibiotic X-14766A 434840 Drug sensitive
Bleomycin-BAPP 431594 Drug resistant
Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide 42640 Drug resistant
Mitoxantrone 4212 Drug resistant
Menadione 4055 Drug sensitive
Purpureagitosid 401298 Drug resistant
1,2 Benzo-8-(1-hydroxy-2-methylamino propane)-3-phenoxazone 400530 Drug sensitive
7,8-Dehydrocalotropin 390666 Drug resistant
Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug sensitive
2-(1-Propynyl)estradiol 388008 Drug sensitive
3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant
Bortezomib 387447 Drug sensitive
3-(4-Fluorophenyl)-3-(4-acetoxy-2-methylphenyl)phthalide 383342 Drug resistant
19-Hydroxy-8-O-methyltetrangulol 379539 Drug sensitive
7-Chloro-6-(2-fluoroethylamino)quinoline-5,8-dione 379079 Drug sensitive
2-(3-Chloropropyloxy)naphthazarin 378771 Drug sensitive
N-(8-Hydroxy-6-methyl-1,4-dioxo-1,4-dihydro-2-naphthalenyl)acetamide 377214 Drug sensitive
2-(2-(Dimethylamino)ethylamino)naphthazarin 376950 Drug sensitive
5,8-Dihydroxy-2-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]naphthalene-1,4-dione 376948 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
2,3-Bis(dodecanoyloxy)propylarsonic acid 375754 Drug sensitive
Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant
3,8,13,18,23-Pentaazapentacosane 368998 Drug sensitive
Diisopropoxybis(1,4-naphthochinone-2-olato)titanium(IV) 368058 Drug sensitive
4-(1-Benzofuran-2-yl)-7-methoxychromen-2-one 364364 Drug resistant
Girolline 362388 Drug resistant
1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)- 362170 Drug sensitive
7alpha-Acetoxyroylenane 362048 Drug sensitive
2,3-Dimethylbenzo[g]quinoxaline-5,10-dione 353644 Drug sensitive
Acronycine, 2-nitro 342903 Drug sensitive
8-Trichloromethyldihydroberberine 320713 Drug sensitive
Dasatinib 3062316 Drug resistant
Deoxycamptothecin 266552 Drug resistant
Gardenin A 261859 Drug resistant
Antimycin A3 245869 Drug sensitive
5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive
1,2-Benzo-8-(L-alanyl)-3-phenoxazone nitrate salt 24202491 Drug sensitive
(2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide 24200489 Drug sensitive
Antibiotic U 29135 24196291 Drug sensitive
Mepacrine mustard dihydrochloride 24180972 Drug resistant
Cytembena 23665583 Drug sensitive
6,7-Dimethoxy-4-(3-hydroxy-4-methylanilino)quinazoline hydrochloride 21701565 Drug resistant
Kinetin riboside 20345 Drug resistant
2,2-Diethyl-6-(hydroxymethyl)-4,6,7,7a-tetrahydro-3aH-[1,3,2]dioxastannolo[4,5-c]pyran-4,7-diol 16683462 Drug sensitive
Trihexyltetradecylphosphonium hexafluorophosphate 16212610 Drug sensitive
Ellipticine analog 148569 Drug resistant
Amphethinile 146332 Drug sensitive
[(1R,5R)-16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl] acetate 146159135 Drug resistant
(2R)-2-Hydroxy-3-[(6R)-11-hydroxy-2-[4-[(6R)-4-hydroxy-2-[1-hydroxy-3-[(6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-methylpropanoic acid 146158002 Drug sensitive
N-[3-[(3-Amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl]-2-[(1S)-18-[(2S)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8,31-bis(1-hydroxyethyl)-26,46-dimethyl-40,43-dimethylidene-6,9,16,23,28,38,41,44,47-nonaoxo-37-propan-2-yl-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecazanonacyclo[23.23.9.329,35.12,5.112,15.119,22.154,57.01,53.032,60]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazole-4-carboxamide 146156820 Drug sensitive
Astrazon Orange R 135747272 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
Formycin b 135449281 Drug resistant
4-[2-[4-(2-Methylprop-1-enyl)-2-oxoindol-3-yl]hydrazinyl]benzenesulfonamide 135409809 Drug resistant
[(8Ar)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylbutanoate 134694047 Drug resistant
(2R,4R,6S,7S,12S)-6,7,16-Trihydroxy-18-methoxy-12-methyl-3,13-dioxatricyclo[13.4.0.02,4]nonadeca-1(15),9,16,18-tetraene-8,14-dione 131676399 Drug sensitive
1,4-Bis((2-aminoethyl)amino)-5,8-dihydroxy-9,10-anthraquinone 125982 Drug resistant
15-Deacetylsergeolide 125729 Drug sensitive
Berberine chloride 12456 Drug sensitive
Pepleo 122804 Drug resistant
Pecilocerin A 118701034 Drug resistant
Unii-C616DV5Y11 117587576 Drug sensitive
Cyanoaminopyranopyridine derivatives 11494577 Drug resistant
3-Bromo-4-(3,3-dimethyl-but-1-ynyl)-2(5H)-furanone 11413833 Drug resistant
(5S,7S)-5,7,9,10-Tetrahydroxy-2-methoxy-7-methyl-6,8-dihydro-5H-anthracene-1,4-dione 11209399 Drug sensitive
1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug resistant
Uridine, 2'-deoxy-2'-methylene- 11075548 Drug resistant
Unii-9JU14BJ5QG 109374088 Drug sensitive
9-Chloro-2-methylellipticinium acetate, hydrate 10383530 Drug resistant
Withajardin C 102469053 Drug sensitive
Cepharanthine 10206 Drug sensitive
(1S,3R,6R,12S,14R,15S,18R,19E,21Z,25R,26S,27R)-6,15-Dihydroxy-18-[(1R)-1-hydroxyethyl]-5,14,26-trimethylspiro[2,10,13,17,24-pentaoxapentacyclo[23.2.1.03,8.08,26.012,14]octacosa-4,19,21-triene-27,2'-oxirane]-11,23-dione 101307863 Drug sensitive
Selumetinib 10127622 Drug sensitive
Chimaphilin 101211 Drug sensitive
(3Z,4R)-4-Hydroxy-3-[2-[(1S,3R)-3-[2-[(1S,3S,3'R,4S)-1-hydroxy-4,6,6-trimethylspiro[2,5-dioxabicyclo[2.2.2]octane-3,6'-oxane]-3'-yl]ethyl]-2,2-dimethyl-6-methylidenecyclohexyl]ethylidene]oxolan-2-one 101206903 Drug sensitive
1,3,6-triphenyl-oxazolo(5,4-d)pyrimidin-2',4(1h,3h)-dion - Drug resistant
1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant
3,7-di(trifluoromethyl)-2-furoylquioxaline 1,4-dioxide - Drug resistant
4-methoxy-2,6-bis[hydroxy(methyl)amino]-1,3,5-triazine - Drug resistant
6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug resistant
indole-2,3-dione, 5-methyl-, 3-[(o-nitrophenyl)hydrazone] - Drug resistant
1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant
6-aryl alkyl fluoro quinolone derivative - Drug resistant
7-pentanoyltaxol - Drug resistant
Annamycin Liposomal - Drug resistant
antineoplastic-d655481 - Drug resistant
geldanamycin dimethylglycinate - Drug resistant
Indenoisoquinoline derivative - Drug resistant
stereoisomer of nsc 675784-h - Drug resistant
tgf.alpha.-pe40 - Drug resistant
toxin .delta.53l - Drug resistant
tp4ek - Drug resistant
tp4ek-k6 - Drug resistant
tunicamycin - Drug resistant
viridomycin - Drug resistant
(z) 3,3',4,5-tetramethoxystilbene - Drug sensitive
1,12-diaziridinyl-4,9-diazadodecane - Drug sensitive
1,2-benzo-8-(d,l-alanyl)-3-phenoxazone nitrate salt - Drug sensitive
1,4-naphthoquinone, 2-chloro-3-furfurylamino- - Drug sensitive
4(1h)-quinazolinone, 2,3-dihydro-2-(1-naphthyl)- (8ci) - Drug sensitive
4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive
4'-deoxy-13',17-dinitro-3',4'-epoxy-vincaleukoblastine - Drug sensitive
4-morpholinecarbodithioic acid, antimony complex - Drug sensitive
5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug sensitive
6-(4-ethylphenyl)-2-(4-(methylsulfonyl)phenyl)-4,5-dihydropyridazin-3(2H)-one - Drug sensitive
7h-5,6-dithioleno[4,3-d]uracil - Drug sensitive
9-cis-retinol,palmitic acid ester - Drug sensitive
9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 2-phenyl- - Drug sensitive
benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate - Drug sensitive
benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive
benzonitrile, 2-amino-3,5-dinitro- (9ci) - Drug sensitive
E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive
iodonium, (4-methoxyphenyl)(3-methylphenyl)-, bromide - Drug sensitive
isoindolo[1,2-b]quinazoline, 10,12-dihydro-3-methyl-12-oxo- - Drug sensitive
naphth[2,3-d]oxazol-9-one, 2-methyl-4-(phenylimino)- - Drug sensitive
naphthalene-1,2-dione, 1,2-dihydro-4-[(3-pyridinyl)amino]- - Drug sensitive
naphthalene-1,2-dione, 4-[(4-bromophenyl)amino]-, 1-oxime - Drug sensitive
naphtho[1,2-c]quinolizinium, 13-methyl-, chloride - Drug sensitive
naphtho[2,3-d]oxazole-4,9-dione, 2-(1,1-dimethylethyl)- - Drug sensitive
phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) - Drug sensitive
thiazolo[3,2-f]phenanthridinium, 3-phenyl- perchlorate - Drug sensitive
thiourea, n-(1-ethylpropyl)-n'-[(2-thienyl)thioxomethyl]- - Drug sensitive
(Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
2-(4-hydroxy-benzylidene)-2-(2-pyridyl)acetonitrile - Drug sensitive
5-hydroxyamino camptothecin - Drug sensitive
6-nitro-1-indazolecarboxy-4'-chloro-2'-anisidide - Drug sensitive
9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive
antineoplastic-615538 - Drug sensitive
antineoplastic-d183258 - Drug sensitive
b705009k098 - Drug sensitive
chalmydocin - Drug sensitive
chlorambucil-spermidine - Drug sensitive
dichlorobisoxinatotitanium(iv) - Drug sensitive
geldanamycin deriv - Drug sensitive
tetra(isobutenyl)antimony bromide - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-502-5p
Oxaliplatine 6857599 Drug interaction    RC00005714
Topotecan 60700 Drug interaction    RC00005711
D-Glucose 5793 Drug interaction    RC00005708
Temozolomide 5394 Drug interaction    RC00005707
Eloxatine 5310940 Drug interaction    RC00005713
Paroxetine 43815 Drug interaction    RC00005710
5-Fluorouracil 3385 Drug interaction    RC00005706
Doxorubicin 31703 Drug interaction    RC00005709
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005705
Verapamil 2520 Drug interaction    RC00005704
Docetaxel 148124 Drug interaction    RC00005712
Leucovorin 135403648 Drug interaction    RC00005715
Mistletoe lectin-I - Drug interaction    RC00005717
1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00005716

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-502-5p
Interactor2: DHODH

Evidence Support:


Strong-Evidence Luciferase reporter assay//qRT-PCR//Western blot
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 33675361 Target region 3'UTR
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line HCT116 cells Interactor2 expression Downregulation
Description In the current study, available miRNAs that regulate drug targets for treating COVID-19 in clinical trials are summarized in Table 2. miRNAs regulate the clinical targets of SARS-CoV-2 in TTD.

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