Detail Information

Basic Information:


  VIRBase ID:  

HHID00105248

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.2494

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-181d-5p:           TMPRSS2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-181d-5p TMPRSS2
miRBase
Accession/Entrez ID		 MIMAT0002821 7113
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - PRSS10

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-181d-5p
rs1486477402 chr19:13874920    G/T
rs201654897 chr19:13874926    G/A
rs534353286 chr19:13874925    C/A
rs534353286 chr19:13874925    C/T
rs1431525802 chr19:13874917    A/G
rs770759381 chr19:13874912    C/T
rs776351139 chr19:13874914    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMPRSS2
chr21:42853862(-) A-I      intronic
chr21:42853848(-) A-I      intronic
chr21:42853888(-) A-I      intronic
chr21:42853850(-) A-I      intronic
chr21:42853879(-) A-I      intronic
chr21:42857482(-) A-I      intronic
chr21:42857493(-) A-I      intronic
chr21:42857494(-) A-I      intronic
chr21:42857532(-) A-I      intronic
chr21:42861840(-) A-I      intronic
chr21:42863176(-) A-I      intronic
chr21:42863181(-) A-I      intronic
chr21:42864020(-) A-I      intronic
chr21:42857454(-) A-I      intronic
chr21:42852821(-) A-I      intronic
chr21:42852811(-) A-I      intronic
chr21:42868840(-) A-I      intronic
chr21:42864037(-) A-I      intronic
chr21:42852802(-) A-I      intronic
chr21:42852784(-) A-I      intronic
chr21:42852783(-) A-I      intronic
chr21:42852698(-) A-I      intronic
chr21:42868853(-) A-I      intronic
chr21:42853773(-) A-I      intronic
chr21:42853747(-) A-I      intronic
chr21:42852838(-) A-I      intronic
chr21:42868879(-) A-I      intronic
chr21:42853786(-) A-I      intronic
chr21:42853787(-) A-I      intronic
chr21:42853866(-) A-I      intronic
chr21:42853876(-) A-I      intronic
chr21:42853901(-) A-I      intronic
chr21:42853902(-) A-I      intronic
chr21:42853905(-) A-I      intronic
chr21:42853936(-) A-I      intronic
chr21:42857436(-) A-I      intronic
chr21:42852837(-) A-I      intronic
chr21:42852694(-) A-I      intronic
chr21:42857467(-) A-I      intronic
chr21:42857468(-) A-I      intronic
chr21:42857476(-) A-I      intronic
chr21:42859902(-) A-I      ncRNA
chr21:42859884(-) A-I      ncRNA
chr21:42859893(-) A-I      ncRNA
chr21:42868835(-) A-I      intronic
chr21:42859992(-) A-I      intronic
chr21:42855936(-) A-I      intronic
chr21:42868944(-) A-I      intronic
chr21:42868836(-) A-I      intronic
chr21:42852668(-) A-I      intronic
chr21:42859993(-) A-I      intronic
chr21:42869010(-) A-I      intronic
chr21:42863353(-) A-I      intronic
chr21:42868900(-) A-I      intronic
chr21:42868945(-) A-I      intronic
chr21:42852703(-) A-I      intronic
chr21:42860827(-) A-I      intronic
chr21:42859858(-) A-I      ncRNA
chr21:42859831(-) A-I      ncRNA
chr21:42859844(-) A-I      ncRNA
chr21:42858403(-) A-I      ncRNA
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TMPRSS2
chr21:42858403(-) A-I intron -    15342557
chr21:42858406(-) A-I intron -    15342557
chr21:42859670(-) A-I intron -    15342557
chr21:42859831(-) A-I intron -    15342557   //15258596
chr21:42859844(-) A-I intron -    15342557   //15258596
chr21:42859858(-) A-I intron -    15342557   //15258596
chr21:42859884(-) A-I intron -    15342557   //15258596
chr21:42859893(-) A-I intron -    15342557   //15258596
chr21:42859902(-) A-I intron -    15342557   //15258596
chr21:42868835(-) A-I intron -    15342557
chr21:42868836(-) A-I intron -    15342557
chr21:42868864(-) A-I intron -    15342557
chr21:42868900(-) A-I intron -    15342557
chr21:42868905(-) A-I intron -    15342557
chr21:42868944(-) A-I intron -    15342557
chr21:42868945(-) A-I intron -    15342557
chr21:42868950(-) A-I intron -    15342557
chr21:42869010(-) A-I intron -    15342557
chr21:42869014(-) A-I intron -    15342557
chr21:42869073(-) A-I intron -    15342557
chr21:42853823(-) A-I intron -    21960545
chr21:42853826(-) A-I intron -    21960545
chr21:42853866(-) A-I intron -    21960545
chr21:42855839(-) A-I intron -    21960545
chr21:42855936(-) A-I intron -    21960545
chr21:42855984(-) A-I intron -    21960545
chr21:42857419(-) A-I intron -    21960545
chr21:42857454(-) A-I intron -    21960545
chr21:42857468(-) A-I intron -    21960545
chr21:42857493(-) A-I intron -    21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMPRSS2
chr21:42836773-42836774(-) m6A 3'UTR       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-181d-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Blood     -
Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
TMPRSS2
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-181d-5p
Iodine Green 9956454 Drug sensitive
Sensorad 99342 Drug sensitive
Piperidine, 2-methyl-6-undecyl- 99090 Drug sensitive
2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive
Oxaliplatin 9887053 Drug sensitive
Saintopin E 9864639 Drug sensitive
5-Iodo-8-quinolinol 96111 Drug sensitive
Triapine 9571836 Drug sensitive
[[4-(3-Aminophenyl)-2-pyridyl]methyleneamino]thiourea 9556427 Drug sensitive
5-Fluorouridine 9427 Drug sensitive
1-(2-Thiazolylazo)-2-naphthol 93572 Drug sensitive
Dichlorodipropylstannane 93562 Drug sensitive
(3Z,8S,11Z,16S)-8,16-Bis(2-oxopropyl)-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetrone 92973777 Drug sensitive
[(1R,2Z,4R,8R,9R,11R,12S)-1,12-Dihydroxy-2-(hydroxymethyl)-11-methyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] (Z)-2-methylbut-2-enoate 90475906 Drug sensitive
Acridine Yellow G 8672 Drug sensitive
4beta-Hydroxywithanolide E 73621 Drug sensitive
Cinerubin B 73593 Drug sensitive
Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive
o-Aminoazotoluene 7340 Drug sensitive
2,3-Piperazinedione 72761 Drug sensitive
Redoxal 72571 Drug sensitive
9-Methoxyellipticine 72512 Drug sensitive
Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive
10,11-Methylenedioxy-20S-camptothecin 72403 Drug sensitive
4-(2-Naphthylamino)phenol 7141 Drug sensitive
Anaxirone 71218 Drug sensitive
Edatrexate 6917908 Drug sensitive
1-(2-Pyridylazo)-2-naphthol 6825 Drug sensitive
2'-Bromo-4'-epi-daunorubicin 6711997 Drug sensitive
NO Data IN this field 6711510 Drug sensitive
(9S)-7-(4-Amino-5-hydroxy-6-methyloxan-2-yl)oxy-9-(2-fluoroacetyl)-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione 6711360 Drug sensitive
Antineoplastic-301477 6711219 Drug sensitive
Rufigallol 65737 Drug sensitive
Fludarabine 657237 Drug sensitive
Reactive Blue 2 656725 Drug sensitive
Ursolic acid 64945 Drug sensitive
(2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive
Rubiflavin 6450217 Drug sensitive
N-(4-Methoxyphenyl)-all-trans-retinamide 6385696 Drug sensitive
1,3,8-Trihydroxy-6-methoxyanthracene-9,10-dione 636723 Drug resistant
Daunorubicin hydrochloride 62770 Drug sensitive
Cytarabine 6253 Drug sensitive
Irinotecan 60838 Drug sensitive
Bizelesin 60794 Drug sensitive
Gemcitabine 60750 Drug sensitive
Topotecan 60700 Drug sensitive
Piriqualone 6015423 Drug sensitive
trans-1,2-Bis(propylsulfonyl)ethylene 5904452 Drug sensitive
Triethylenemelamine 5799 Drug sensitive
Cisplatin 5702198 Drug sensitive
Teclothiazide potassium 56841138 Drug sensitive
(3beta)-3-((4-O-beta-D Glucopyranosyl-beta-D-xylopyranosyl)oxy)-14-hydroxy-19-oxocarda-4,20(22)-dienolide 56840951 Drug sensitive
Adenosine, 2-bromo-2'-deoxy- 55914 Drug sensitive
Dezaguanine 55710 Drug sensitive
Caracemide 54747 Drug sensitive
Artelasticin 5471311 Drug sensitive
Kijanimicin sodium salt 54707591 Drug sensitive
3-Deazauridine 54684286 Drug sensitive
(8R,9S,13S,14S,17S)-13-Methyl-2-[(E)-prop-1-enyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 5468270 Drug sensitive
(Z)-4-Bromo-4-iodo-3-phenylbut-3-en-2-one 5467656 Drug sensitive
Curromycin A.B mixture 54608021 Drug sensitive
Biantrazole 54607781 Drug sensitive
Antineoplastic-651590 54604785 Drug sensitive
(1S,2R,4R,7E,9R)-9-Hydroxy-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one 54600951 Drug sensitive
Betuletol 5459196 Drug sensitive
(E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive
Crassin, acetate 5355441 Drug sensitive
MX2 hydrochloride 5351347 Drug sensitive
Improsulfan hydrochloride 5284401 Drug sensitive
Amonafide 50515 Drug sensitive
Kekule 499328 Drug sensitive
Ammonia; dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498559 Drug sensitive
Elsinochrome C 495866 Drug sensitive
Hopeaphenol 495605 Drug resistant
Methoxycamptothecin 494089 Drug sensitive
Dioxadet 48858 Drug sensitive
Epidoxoform 46877760 Drug sensitive
1,4-Benzoquinone 4650 Drug sensitive
N'-(3-Pyridin-2-ylisoquinolin-1-yl)pyridine-2-carboximidamide 463108 Drug sensitive
Melphalan 460612 Drug sensitive
Benzamide riboside 458027 Drug sensitive
Aphidicolin 457964 Drug sensitive
Aclarubicin 451415 Drug sensitive
Ossirene 451379 Drug sensitive
BAS100 Monohydrate 45028404 Drug sensitive
5-Fluoro-2'-deoxyuridyly-(3'->5')-3'-C-ethynylcytosine 45028394 Drug sensitive
1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive
Isopinnatal 44558939 Drug sensitive
Elephantin 442205 Drug sensitive
Methyl 4-[4-(dimethylamino)-5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxooxan-2-yl)oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate 438788 Drug sensitive
Physalolactone 433866 Drug sensitive
Oridonin (thiol adduct OF) 432952 Drug sensitive
Di-n-octyl-secalonsaure A 430141 Drug sensitive
10-Hydroxy-5-methoxy-1-(2-methyloxiran-2-yl)-1,2-dihydrofuro[2,3-c]xanthen-6-one 429905 Drug sensitive
Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide 42640 Drug sensitive
Diaziquone 42616 Drug sensitive
Mitoxantrone 4212 Drug sensitive
trans-Bis(acetato)amminepyridineplatinum(II) 405450 Drug sensitive
2-[(Phenylamino)methyl]benzene-1,4-diol 403336 Drug sensitive
Mechlorethamine 4033 Drug sensitive
3-Iodoacetamido-benzoic acid ethyl ester 398530 Drug sensitive
1H-Indole, 5-bromo-3-[2-(2-pyridinyl)-4-thiazolyl]- 397551 Drug sensitive
Lomustine 3950 Drug sensitive
2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive
Sjg-136 393111 Drug sensitive
Antineoplastic-690271 391308 Drug sensitive
5,8-Quinolinedione, 2-methyl- 388305 Drug sensitive
1,3-Diphenyl-6-((triphenylphosphoranylidene)amino)-2,4(1H,3H)-pyrimidinedione 387460 Drug sensitive
Pyrimidin-2-amine, 4-(2-hydroxy-4-methoxyphenyl)-6-phenyl- 386505 Drug sensitive
L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive
1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive
N,N-Bis(2-chloropropyl)-N-methylammonium chloride 381678 Drug sensitive
(1R)-3,3-Dibromocamphor 376765 Drug sensitive
Cycloalkannin 375418 Drug sensitive
3,8-Dimethyl-1,2-naphthoquinone 373912 Drug sensitive
Antineoplastic-D648114 372647 Drug sensitive
Jasplakinolide epoxide C 372550 Drug sensitive
N-Hydroxy-N-methylpropanethioamide 371713 Drug sensitive
O-Benzylfluorescein benzyl ester 371436 Drug sensitive
11H-Benzo[a]carbazole-1,4-dione, 7,11-dimethyl- 371271 Drug sensitive
Diselenide, bis(4-methylphenyl) 365239 Drug sensitive
Amchlorguanidine 364435 Drug sensitive
4-Aza-2'-phenyl-5alpha-cholestano[3,2-c]pyrazole 363170 Drug sensitive
7,12-Epidioxybenz[a]anthracene, 7,12-dihydro-7-methyl- 362095 Drug sensitive
Antineoplastic-615804 355949 Drug sensitive
1-Chloro-3-(3-chloropropylsulfonylsulfanyl)propane 355643 Drug sensitive
6,7-Diacetoxyisoflavan 353129 Drug sensitive
5-Fluorocytosine arabinoside 352938 Drug sensitive
2-Isopropenyl-4,6-diphenoxy-1,3,5-triazine 340916 Drug sensitive
Nicomol 34081 Drug sensitive
Pyrazoloacridine 339455 Drug sensitive
4-Ethyl-6-methoxy-7-(oxiran-2-ylmethoxy)quinazoline 333565 Drug sensitive
Phenyl gallate 333279 Drug sensitive
2,4-Diamino-5-(3-amino-4-chloro-5-nitrophenyl)-6-ethylpyrimidine 327404 Drug sensitive
Pinafide 327045 Drug sensitive
Rustaiyan A 324967 Drug sensitive
6-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)sulfanyl]-7H-purin-2-amine 3246652 Drug sensitive
Dmask 32465 Drug sensitive
Hydroxypristimerin 320914 Drug sensitive
Butanedioic acid, 2-bromo-3-fluoro-, dimethyl ester 317895 Drug sensitive
2,2',3,3'-Tetrahydroxy-1,1'-binaphthyl 316673 Drug sensitive
5-Cinnamylidene-1,3-thiazolidine-2,4-dione 315044 Drug sensitive
2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive
Cytosine arabinoside monophosphate 314 Drug sensitive
1,4-Naphthalenedione, 5,8-dihydroxy-2,3-bis(hydroxymethyl)- 313371 Drug sensitive
N,N-Dibenzyldaunorubicin 3081598 Drug sensitive
Cytosine, 1beta-D-arabinofuranosyl-N(sup 4)-stearoyl- 304673 Drug sensitive
Flurocitabine 3034016 Drug sensitive
Daunorubicin 30323 Drug sensitive
[(5Z)-1,7,7-Trimethyl-5-(nitromethylene)-6-oxo-norbornan-2-yl] acetate 3004516 Drug sensitive
1,1-Dimethyl-5-(2-naphthalenyl)dithiobiuret 3004012 Drug sensitive
2,3-Bis(iodomethyl)-6-methoxyquinoxaline 286257 Drug sensitive
Dichloroallyl lawsone 277767 Drug sensitive
Digoxin 2724385 Drug sensitive
Chlorambucil 2708 Drug sensitive
Deoxycamptothecin 266552 Drug sensitive
1-(2-Chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea 26328 Drug sensitive
Gitoxoside 261947 Drug sensitive
1H-Benzo[a]carbazole-1,4(11H)-dione, 11-methyl- 261066 Drug sensitive
2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive
2-(7-Aminotriazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol 251928 Drug sensitive
Hydrazine sulfate 24842 Drug sensitive
Camptothecin 24360 Drug sensitive
1-(3-Bromo-phenyl)-3-(pyridin-2-ylsulfanyl)-propenone 24203485 Drug sensitive
Prumycin HCl 24197905 Drug resistant
Mepacrine mustard dihydrochloride 24180972 Drug sensitive
9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive
[(1R,2S,4R,6R,7R,10S,11R,14S,16S)-16-Hydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-14-yl] acetate 23618199 Drug sensitive
[(1S,2Z,4R,8R,9R,11R,13S)-13-Acetyloxy-1-hydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] 2-methylpropanoate 23255746 Drug sensitive
(2-Bromoethyl)triphenylphosphonium bromide 22210408 Drug sensitive
4-[[(8-Hydroxyquinolin-7-yl)-phenylmethyl]amino]benzoic acid 219564 Drug sensitive
Amsacrine 2179 Drug sensitive
Diethylcarbamodithioic acid, sodium salt 21192315 Drug sensitive
Pirarubicin hydrochloride 20846247 Drug sensitive
Cladribine 20279 Drug sensitive
(p-Nitrophenyl)phenyliodonium bromide 19992 Drug sensitive
8-Hydroxyquinoline 1923 Drug sensitive
Sudan II 18386 Drug sensitive
8-Chloro-cyclicamp 17856967 Drug sensitive
P-Dioxane,5-bis[(benzoyloxymercuri)methyl]- 16683647 Drug sensitive
4H-1,3,2-Benzodioxastannin-4-one, 7-amino-2,2-diphenyl- 16683127 Drug sensitive
4H-1,3,2-Benzodioxastannin-4-one, 7-amino-2,2-dibutyl- 16683126 Drug sensitive
Azaribine 16574 Drug sensitive
1,2:5,6-Dianhydrogalactitol 15942827 Drug sensitive
Thevetin 159331 Drug sensitive
(3As,3bR)-3b-hydroxy-3a,5,5-trimethyl-3-methylidene-4H-cyclopenta[a]pentalene-2,6-dione 15699597 Drug sensitive
(2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive
[(1S,2R,3R,4R,6S,8S,9R,10S,11S,13R)-2,8-Diacetyloxy-3,6-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 153274253 Drug sensitive
Aklavin 149755 Drug sensitive
Sulfanilanilide, 4'-(9-acridinylamino)- 148802 Drug sensitive
Ellipticine analog 148569 Drug sensitive
(1R,16R)-6-Hydroxy-19-(1H-indol-3-ylmethyl)-7,9,16,17-tetramethyl-15-oxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-3,7,11-triene-2,5,21-trione 146159025 Drug sensitive
[6-[(12R)-12-Acetyloxy-10-[(4S)-5-acetyloxy-4-(dimethylamino)-4,6-dimethyloxan-2-yl]-2-but-2-en-2-yl-11-hydroxy-12-methoxy-5-methyl-4,7-dioxonaphtho[7,6-h]chromen-8-yl]-4-(dimethylamino)-2-methyloxan-3-yl] acetate 146158821 Drug sensitive
(5S,10S,13R,14S)-3-[3,4-Dihydroxy-6-methyl-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,14-dihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde 146156945 Drug sensitive
Diphenyltin dichloride 14342 Drug sensitive
Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive
Acid Alizarine Red B 135565636 Drug sensitive
12-Iminodaunorubicin hcl 135539784 Drug sensitive
2,4-Dihydroxybenzaldehyde 2-pyridylhydrazone 135509512 Drug sensitive
Oxanthrazole 135502299 Drug sensitive
5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive
Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive
7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 3,4-dihydro-3-beta-D-ribofuranosyl-(9CI) 135492361 Drug sensitive
Emofolin sodium 135475347 Drug sensitive
1-Phenazinecarboxylic acid, 6-formyl-4,7,9-trihydroxy-, methyl ester 135457300 Drug sensitive
Kinamycin C 135430800 Drug sensitive
N-Cyano-N'-methacryloylguanidine 135429904 Drug sensitive
7-Nitro-1,2,4-benzotriazin-3-amine 1,4-dioxide 135427573 Drug sensitive
Pyrazofurin 135413551 Drug sensitive
8-Azahypoxanthine 135410720 Drug sensitive
3-Nitro-benzoic acid (2-hydroxy-benzylidene)-hydrazide 135408681 Drug sensitive
2-Chloro-3-(2-butoxyethoxy)naphthazarin 135406263 Drug sensitive
Allopurinol 135401907 Drug sensitive
DTIC-Dome 135398738 Drug sensitive
(1R,2S,5S,8S,9S,17R,18R,21S,24R,26S,27S)-14-Chloro-5,15-dihydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacos-11-ene-4,10,22,29-tetrone 134715214 Drug sensitive
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Diacetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[[(E)-2-methylbut-2-enoyl]amino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-9-[(3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate 134714918 Drug sensitive
Saintopin 131350 Drug sensitive
(2Z)-3-Ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methylprop-2-enylidene]-1,3-benzothiazole;hydroiodide 129893658 Drug sensitive
Terpentecin 127568 Drug sensitive
gamma-Thujaplicin 12649 Drug sensitive
1,4-Bis((2-aminoethyl)amino)-5,8-dihydroxy-9,10-anthraquinone 125982 Drug sensitive
Cytochalasin q 11970174 Drug sensitive
Melampodinin 11953936 Drug sensitive
Indotecan 11533060 Drug sensitive
1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug sensitive
p-Toluquinone 11122 Drug sensitive
Gentian violet 11057 Drug sensitive
[(1R,3R,5R,8R,9S,10R,13R,14S,17R)-3-[(2R,3R,4R,5R,6S)-3,5-Dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-10,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-1-yl] acetate 101973931 Drug sensitive
(7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive
(1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive
N,N-Bis(2-chloroethyl)-p-toluidine 100400 Drug sensitive
Cinnoline, 4-nitro-, 1-oxide 100397 Drug sensitive
Tocladesine 100299 Drug sensitive
(1R,2E,6R,10E,11aS,13S,14aR)-1,13-dihydroxy-6-(2-methoxyethyl)-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one - Drug resistant
(1R,2E,6R,10E,11aS,13S,14aR)-6-(2-(benzyloxy)ethyl)-1,13-dihydroxy-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one - Drug resistant
(1R,6S,11aS,13S,14aR)-1,13-dihydroxy-6-vinyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one - Drug resistant
(1s,2e,4r,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug sensitive
(1s,2e,4r,7e,11e)-4-hydroxy-2,7,11-cembratrien-6-one - Drug sensitive
(1s,2e,4s,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug sensitive
(2r,3r)-(+)-methyl 3-phenyloxirane-carboxylate - Drug sensitive
1,2-naphthoquinone, 3,7-dimethyl- - Drug sensitive
1,3,5-triazin-2-amine, 4,6-dimethoxy-n-phenyl- - Drug sensitive
1,3-isoquinolinedione, 4-[(3,4-dimethoxyphenyl)methylene]- - Drug sensitive
1,4-bis(n-cysteinyldiethylamino)-5,8-dihydroxy anthraquinon - Drug sensitive
1,8-octanediamine, n,n'-di-9-acridinyl- (9ci) - Drug sensitive
1h-1,2,4-triazole, 3-(4-diazo-4h-imidazol-5-yl)- - Drug sensitive
1h-benzo[a]carbazole-1,4(11h)-dione, 11-phenyl- - Drug sensitive
2,3-butanediol, 1,4-bis(2-methyl-1-aziridinyl)- (8ci) - Drug sensitive
2,6-bis(4-morpholinylmethyl)cyclohexanone,dihydrochloride - Drug sensitive
2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive
2-bromo-5,8-dihydroxy-3-methyl-1,4-naphthoquinone - Drug sensitive
2h-naphtho[1,2-b]pyran-2-one, 9-hydroxy-4-phenyl- - Drug sensitive
2-propenone, 1,1'-(2,5-pyridinediyl)bis[3-(2-furanyl)- - Drug sensitive
3,3?-(1h-pyrrole-2,5-diyl)bis(5-chloro-1-methyl-1h-indole) - Drug sensitive
3',4',5'-trimethoxy-3-hydroxy flavone - Drug sensitive
3,7-di(trifluoromethyl)-2-furoylquioxaline 1,4-dioxide - Drug sensitive
4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive
4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive
5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive
9,10-anthracenedione, 1-[(oxiranylmethyl)amino]- - Drug sensitive
acetamide, n-(2-mercaptoethyl)-, benzoate (6ci, 7ci) - Drug sensitive
aquatris(1,3-diphenylpropane-1,3-dionato)neodymium(iii) - Drug sensitive
benzene, 1,1'-[(1,3-butadiene-1,4-diyl)sulfonyl]bis - Drug sensitive
benzofurazan, 5-nitro-6-(1-piperidinyl)-, 1-oxide - Drug sensitive
bersaldegenin 1,3,5-orthoacetate - Drug sensitive
c4, carbonyl, ethyl prodigiosine - Drug sensitive
cholestan-5.alpha.-ol-3,6-dione - Drug sensitive
cyclopentanone, 2,5-bis[(trimethylamino)methyl]-, iodide - Drug sensitive
dichloro(dodeca-2,6,10-triene-1,12-diyl)- ruthenium - Drug sensitive
dimethylarsinothious acid, 2,4-pyrimidinediyl ester - Drug sensitive
ethanone, 1-(2-pyrimidinyl)-, (2-benzoxazolyl)hydrazone - Drug sensitive
ethyl-2,3-oxido-(5-bromo-2-methoxyphenyl)propionate - Drug sensitive
furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive
isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive
n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive
n,n'-di-9-acridinyl-1,6-hexanediamine - Drug sensitive
phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive
phosphonium, triphenyl-1,2-propadienyl-, bromide (9ci) - Drug sensitive
piceatannol, 4,3',5'-trimethyl,1s0 - Drug sensitive
propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive
propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive
pyrido[3',4':4,5]thieno[2,3-g]isoquinoline, 6-methyl- - Drug sensitive
sulfide, 2,4-dinitrophenyl 2-nitro-p-tolyl - Drug sensitive
tellurium, trichloro[1,2-hexanedioato(2-)-o,o']-, ammonium - Drug sensitive
tricyclo[4.4.0.0(2,7)]decane-5-one, 4,4-dibromo-2-methyl- - Drug sensitive
tris(1,3-diphenylpropane-1,3-dionata)gallium(iii) - Drug sensitive
[bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive
1-[(4-aminophenyl)-(4-hydroxyphenyl)methylidene]-[3]ferrocenophane - Drug sensitive
2-(n-d-glysoyl)aminobenzothiazole - Drug sensitive
2'-o-(all trans)-retinoyl-erythromicine a - Drug sensitive
3-farnesylthiopropionamide - Drug sensitive
4-bromo-2-(2-hydroxy-3-methyl-3-butenyl)phenol - Drug sensitive
4-carbo-1-thiazolidine-3-o-gluconyl-.gamma.-lactone - Drug sensitive
4'-chloro-3-nitro-o-salicylotoluidide - Drug sensitive
7-propanoyltaxol - Drug sensitive
actinomycin pip t.beta. - Drug sensitive
allylgutimine - Drug sensitive
Aminocamptothecin - Drug sensitive
analog of cc-1065 - Drug sensitive
Annamycin Liposomal - Drug sensitive
Anthrapyrazole derivative - Drug sensitive
antineoplastic-d665839 - Drug sensitive
Aphidicoline glycinate - Drug sensitive
arylpurine derivatives - Drug sensitive
Camptothecin Derivative - Drug sensitive
Carboqone; Carbazilquinone - Drug sensitive
Carboxyphthalatoplatinum - Drug sensitive
CI-921: amsacrine derivative - Drug sensitive
cyclo [n-naphthoyl-d-lys-asn-gln-trp-ala-val-d-ala-his-leu] - Drug sensitive
from cephalodiscus gilchristi - Drug sensitive
hymenialdisine - Drug sensitive
Indenoisoquinoline derivative - Drug sensitive
insulin-methotrexate conjugate - Drug sensitive
kaurane deriv - Drug sensitive
largomycin f-ii - Drug sensitive
merophan - Drug sensitive
methyl 3-farnesylthioacetate - Drug sensitive
methyl green - Drug sensitive
o-linoleoyl-2-butoxy-1-desoamine - Drug sensitive
orlistat (usan) - Drug sensitive
pneumocandin c(sub 0) - Drug sensitive
potassium[trichloro(isopropylamine)platinum] - Drug sensitive
stereoisomer of nsc 675784-h - Drug sensitive
thiadiazines - Drug sensitive
thiostrepton (usan) - Drug sensitive
trans-dichlorobis(tricyclohexylphosphine)palladium - Drug sensitive
trimethyl(phenylthio)stannane - Drug sensitive
viridomycin - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-181d-5p
Curcumin 969516 Drug interaction    RC00005500
Formaldehyde 712 Drug interaction    RC00005482
Gemcitabine 60750 Drug interaction    RC00005494
Vincristine 5978 Drug interaction    RC00005489
Mitomycin 5746 Drug interaction    RC00005488
Temozolomide 5394 Drug interaction    RC00005487
Eloxatine 5310940 Drug interaction    RC00005502
Imatinib 5291 Drug interaction    RC00005486
Decitabine 451668 Drug interaction    RC00005499
Diethylstilbestrol 448537 Drug interaction    RC00005498
Trichostatin A 444732 Drug interaction    RC00005497
Carboplatinum 38904 Drug interaction    RC00005493
5-Fluorouracil 3385 Drug interaction    RC00005485
Doxorubicin 31703 Drug interaction    RC00005492
Ursodeoxycholic acid 31401 Drug interaction    RC00005491
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005484
Tamoxifen 2733526 Drug interaction    RC00005501
Verapamil 2520 Drug interaction    RC00005483
Arsenic trioxide 14888 Drug interaction    RC00005490
Docetaxel 148124 Drug interaction    RC00005496
Gefitinib 123631 Drug interaction    RC00005495
5-aza-2'-deoxycytidine (5-Aza-CdR) + trichostatin A(TSA) - Drug interaction    RC00005503
Aidi injection - Drug interaction    RC00005504

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-181d-5p
Interactor2: TMPRSS2

Evidence Support:


Prediction-Evidence microT//miRanda//miRMap//PicTar//PITA//Targetscan
Support Database ViRBase

References:


PMID 33428154 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description To explore the regulatory relationship between the 5 key genes, 3 coronavirus-related genes (ACE2, TMPRSS2, BSG), and their target miRNA, we used 6 miRNA target prediction databases to predict the target miRNA of these genes.

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