Detail Information

Basic Information:


  VIRBase ID:  

HHID00105229

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-329-3p:           ACE2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-329-3p ACE2
miRBase
Accession/Entrez ID		 MIMAT0001629 59272
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ACEH

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-329-3p
rs1482145565 chr14:101026844    G/A
rs746976076 chr14:101026850    C/G
rs771646192 chr14:101026843    G/GGTT
rs777650156 chr14:101026848    A/G
rs1005677370 chr14:101027167    C/A
rs1005677370 chr14:101027167    C/T
rs1158749175 chr14:101027166    C/T
rs1390123068 chr14:101027170    T/A
rs1417718813 chr14:101027162    T/G
rs746510028 chr14:101027169    CTT/C
rs751364425 chr14:101027168    T/G
rs761786400 chr14:101027171    T/C
rs1331356830 chr14:101026838    C/T
rs1343998667 chr14:101026841    C/T
rs1430285618 chr14:101026836    C/T
rs1416165952 chr14:101027158    C/T
rs762603030 chr14:101027156    A/G
rs763867095 chr14:101027157    C/G
rs763867095 chr14:101027157    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ACE2
chrX:15579319-15579320(-) m6A 3'UTR//exon       27773535
chrX:15579343-15579344(-) m6A 3'UTR//exon       27773535
chrX:15579366-15579367(-) m6A 3'UTR//exon       27773535
chrX:15579420-15579421(-) m6A 3'UTR//exon       27773535
chrX:15579431-15579432(-) m6A 3'UTR//intron       27773535
chrX:15579618-15579619(-) m6A 3'UTR//intron       27773535
chrX:15579631-15579632(-) m6A 3'UTR//intron       27773535
chrX:15579696-15579697(-) m6A 3'UTR//exon       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-329-3p
Exosome Serum     18589210
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Blood     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Blood|Fibroblasts|Mesenchymal stem cells     -
ACE2
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-329-3p
8-Aminoadenosine 96851 Drug resistant
Actinomycin X4357G methoxime 9573583 Drug sensitive
1,9-Pyrazoloanthrone 8515 Drug resistant
Berberine iodide 72350 Drug sensitive
1,3,5-Triacryloylhexahydro-1,3,5-triazine 70397 Drug resistant
3-[[4-[[2-(Methoxycarbonylamino)-3H-benzimidazol-5-yl]oxy]phenyl]carbamoylamino]benzoic acid;hydrochloride 57399799 Drug sensitive
2,3-Diphenyl-1,4-naphthoquinone 555037 Drug sensitive
2-Azaadenine 5480214 Drug resistant
Antibiotic 1907-VIII 5477807 Drug sensitive
8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug sensitive
2-(1,3-Benzodioxol-5-yl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one 5466137 Drug sensitive
Varacin trifluoroacetate salt 54611558 Drug resistant
2-Methylolivacinium acetate 5458752 Drug sensitive
Xestin A 5352066 Drug resistant
Berberal 5351462 Drug sensitive
5-Methyl-2-{[(2)-3-phenylprop-2-enoyl]amino}benzamide 53329052 Drug sensitive
6-Bromosangivamycin 470030 Drug resistant
Suavedol 442245 Drug resistant
Musennin 441933 Drug sensitive
Isobrucein A 441802 Drug sensitive
Antibiotic X-14766A 434840 Drug sensitive
Elliptinium acetate 42722 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
2-N-Methyl-6-thiaellipticinum iodide 367888 Drug sensitive
1,1-Dioxido-1,5-benzothiazepin-4-yl methyl ether 358940 Drug resistant
Haloprogin 3561 Drug resistant
Maxima isoflavone D 343081 Drug sensitive
Ellipticine 3213 Drug sensitive
8-Trichloromethyldihydroberberine 320713 Drug sensitive
2-(2-(Diethylamino)ethyl)-9-hydroxy-5,11-dimethyl-6H-pyrido(4,3-b)carbazolium acetate 3086131 Drug sensitive
4,6-Diamino-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile 300567 Drug resistant
Sarcoviolin 24202820 Drug sensitive
Kinetin riboside 20345 Drug resistant
(R)-(2,8-Bis(trifluoromethyl)quinolin-4-yl)((S)-piperidin-2-yl)methanol hydrochloride 18660697 Drug resistant
{4-[5-(4-Fluoro-phenyl)-3-(1-methyl-piperidin-4-yl)-3H-imidazol-4-yl]-pyrimidin-2-yl}-phenyl-amine 17892742 Drug resistant
(1S,3R,5R,9R,10R)-5-Ethenyl-2,3,9,10-tetrahydroxy-5,11,11-trimethyl-16-oxatetracyclo[7.5.2.01,10.02,7]hexadec-6-en-8-one 139587002 Drug resistant
Acid Alizarine Red B 135565636 Drug sensitive
Formycin b 135449281 Drug resistant
Salicylidene salicylhydrazide 135445765 Drug resistant
43-Dioxypectenotoxin 131751434 Drug sensitive
15-Deacetylsergeolide 125729 Drug sensitive
Berberine chloride 12456 Drug sensitive
Litmomycin 12310334 Drug resistant
3-Bromo-4-(3,3-dimethyl-but-1-ynyl)-2(5H)-furanone 11413833 Drug resistant
Unii-9JU14BJ5QG 109374088 Drug sensitive
2-N-Methyl-6-oxaellipticinium acetate 10018975 Drug sensitive
1,6:2,3-dianhydro-4-o-benzyl-.beta.-d-mannopyranose - Drug resistant
inosine, 6-thio-, 2',3',5'-tripentanoate - Drug resistant
1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant
2-bromo-3-ketocastanospermine - Drug resistant
E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive
naphtho[1,2-b]quinolizinium, 9-methyl-, bromide - Drug sensitive
phosphonium, triphenylpropenyl-, bromide, (e)- (8ci) - Drug sensitive
2-(4-hydroxy-benzylidene)-2-(2-pyridyl)acetonitrile - Drug sensitive
2-methylellpticinium - Drug sensitive
9-(3-fluorobenzyl)-7-(3-fluorobenzyloxy)-2-(4-fluorobenzyl)-1-methyl-9H-beta-carbolinium bromide - Drug sensitive
n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive
protein: pahiv4 - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-329-3p
Gemcitabine 60750 Drug interaction    RC00005078
D-Glucose 5793 Drug interaction    RC00005076
Doxorubicin 31703 Drug interaction    RC00005077

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-329-3p
Interactor2: ACE2

Evidence Support:


Prediction-Evidence miRanda//miRBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32992681 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Table 1 shows a list of novel potential candidate miRNAs against ACE2 gene that were not studied previously.

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