Basic Information:
VIRBase ID: HHID00105035
Virus: SARS-CoV-2
Host: Homo sapiens
Confidence Score: 0.1828
Interaction Type: Host-Host interaction
Interactor Information:
Interactor1
Interactor2
Symbol
hsa-let-7a-g
TMPRSS2
miRBase Accession/Entrez ID
hsa-let-7a-g
7113
Organism
Homo sapiens
Homo sapiens
Category
miRNA
mRNA
Alias
-
PRSS10
RNA Editing:
Resource
Symbol
Editing Position
Change
Genetic Region
RADAR
TMPRSS2
Resource
Symbol
Editing Position
Change
SeqReg
exReg
PMID
DARNED
TMPRSS2
RNA Modification:
Resource
Symbol
ModificationPosition
Type
Genomic Context
PMID
RMBase
TMPRSS2
RNA Localization:
Resource
Symbol
Subcellular Localization
Tissue or Cell Line
PMID
RNALocate
TMPRSS2
Interaction Network (The top 100 interactions) :
Interactor1: hsa-let-7a-g
Interactor2: TMPRSS2
Evidence Support:
Prediction-Evidence
Targetscan
Support Database
ViRBase
References:
PMID
32672403
Target region
None
Source
ViRBase
Interactor1 expression
None
Tissue or cell line
None
Interactor2 expression
None
Description
Hence, the potential role of these gender-associated miRNAs in immunity regulation and in modulation of viral receptors and co-receptors should be considered as a crucial factor in the observed different pathogenicity and lethality of COVID-19 in men and women (see Table 1).