Detail Information

Basic Information:


  VIRBase ID:  

HHID00105026

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      IFNG-AS1:           IFNG:      

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Interactor Information:


Interactor1 Interactor2
Symbol IFNG-AS1 IFNG
miRBase
Accession/Entrez ID		 100885789 3458
Organism Homo sapiens Homo sapiens
Category lncRNA mRNA
Alias GS1-410F4.2//NEST//Tmevpg1 IFG//IFI//IMD69

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IFNG
chr12:68548714-68548715(-) m6A 3'UTR       26404942
chr12:68548719-68548720(-) m6A 3'UTR       26404942
chr12:68548806-68548807(-) m6A 3'UTR       26404942
chr12:68549044-68549045(-) m6A 3'UTR       26404942
chr12:68549188-68549189(-) m6A CDS       26404942
chr12:68549207-68549208(-) m6A CDS       26404942
chr12:68549228-68549229(-) m6A CDS       26404942
chr12:68551762-68551763(-) m6A CDS       26404942
chr12:68551775-68551776(-) m6A CDS       26404942
chr12:68551813-68551814(-) m6A CDS       26404942
chr12:68551824-68551825(-) m6A CDS       26404942
chr12:68552005-68552006(-) m6A CDS       26404942
chr12:68553297-68553298(-) m6A CDS       26404942
chr12:68553321-68553322(-) m6A CDS       26404942
chr12:68553436-68553437(-) m6A 5'UTR       26404942
chr12:68553458-68553459(-) m6A 5'UTR       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate IFNG-AS1
Exosome Blood     -
IFNG
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug IFNG-AS1
Panobinostat       6918837
Irinotecan       60838
Topotecan       60700
l-685,458       5479543
Palbociclib       5330286
5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120
Pha-665752       10461815

Interaction Network (The top 100 interactions):


Interactor1: IFNG-AS1
Interactor2: IFNG

Evidence Support:


Prediction-Evidence LncRNA2Target
Support Database ViRBase

References:


PMID 33520952 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description We identified a total of 24 cytokine-lncRNA relationships using LncRNA2Target (Table 2). The most significant lncRNAs associated with COVID-19 cytokine storm cytokines, accompanied by lncRNA target prediction analysis using average ndG values.

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