Basic Information:

  VIRBase ID:  

HHID00105006

  Virus:  

SARS-CoV-2

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      DRAIC:  NR_026979          IL2:  NM_000586     

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Interactor Information:

	Interactor1	Interactor2
Symbol	DRAIC	IL2
miRBase Accession/Entrez ID	145837	3558
Organism	Homo sapiens	Homo sapiens
Category	lncRNA	mRNA
Alias	-	IL-2//lymphokine//TCGF

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DRAIC	chr15:69858379(+) A-I      intronic chr15:69860434(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DRAIC	chr15:69863604-69863605(+) m6A exon       24981863 chr15:69863618-69863619(+) m6A exon       24981863 chr15:69863659-69863660(+) m6A exon       24981863 chr15:69863666-69863667(+) m6A exon       24981863 chr15:69863732-69863733(+) m6A exon       24981863
	IL2	chr4:123372952-123372953(-) m6A CDS//exon       26404942 chr4:123372977-123372978(-) m6A CDS//exon       26404942 chr4:123373007-123373008(-) m6A CDS//exon       26404942 chr4:123374870-123374871(-) m6A CDS//exon       26404942 chr4:123374904-123374905(-) m6A CDS//exon       26404942 chr4:123374912-123374913(-) m6A CDS//exon       26404942 chr4:123374925-123374926(-) m6A CDS//exon       26404942 chr4:123374963-123374964(-) m6A CDS//exon       26404942 chr4:123374969-123374970(-) m6A CDS//exon       26404942 chr4:123374993-123374994(-) m6A CDS//exon       26404942 chr4:123374999-123375000(-) m6A CDS//exon       26404942 chr4:123377507-123377508(-) m6A CDS//exon       26404942 chr4:123377539-123377540(-) m6A CDS//exon       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	DRAIC	Exosome Blood     -
	IL2	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: DRAIC
Interactor2: IL2

Evidence Support:

Prediction-Evidence	LncRNA2Target
Support Database	ViRBase

References:

PMID	33520952	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	None	Interactor2 expression	None
Description	We identified a total of 24 cytokine-lncRNA relationships using LncRNA2Target (Table 2). The most significant lncRNAs associated with COVID-19 cytokine storm cytokines, accompanied by lncRNA target prediction analysis using average ndG values.