Detail Information

Basic Information:


  VIRBase ID:  

HHID00099605

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           ZBTB42:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p ZBTB42
miRBase
Accession/Entrez ID		 MIMAT0027574 100128927
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - LCCS6//ZNF925

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZBTB42
chr14:105270278(+) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZBTB42
chr14:105270278(+) A-I exon 3'UTR    19478186   //21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZBTB42
chr14:105267697-105267698(+) m6A CDS       24981863
chr14:105267775-105267776(+) m6A CDS       24284625//25456834//24981863
chr14:105267799-105267800(+) m6A CDS       24284625//25456834//24981863//22608085
chr14:105267910-105267911(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr14:105267919-105267920(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr14:105267938-105267939(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr14:105267972-105267973(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr14:105267979-105267980(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr14:105268087-105268088(+) m6A CDS       24284625//25456834//24981863//22608085
chr14:105268099-105268100(+) m6A CDS       24284625//25456834//24981863//22608085
chr14:105268158-105268159(+) m6A CDS       24284625//25456834//24981863//22608085
chr14:105268216-105268217(+) m6A CDS       24284625//25456834//24981863//22608085
chr14:105268229-105268230(+) m6A CDS       24284625//25456834//24981863//22608085
chr14:105268495-105268496(+) m6A CDS       24284625//25456834//24981863//22608085
chr14:105268557-105268558(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr14:105268596-105268597(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr14:105268744-105268745(+) m6A CDS       24284625//25456834//24981863//22608085
chr14:105268863-105268864(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr14:105268959-105268960(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr14:105268971-105268972(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr14:105269305-105269306(+) m6A 3'UTR       24981863
chr14:105269310-105269311(+) m6A 3'UTR       24981863
chr14:105269335-105269336(+) m6A 3'UTR       24981863
chr14:105269573-105269574(+) m6A 3'UTR       24981863
chr14:105269974-105269975(+) m6A 3'UTR       24284625//25456834//24981863
chr14:105269989-105269990(+) m6A 3'UTR       24284625//25456834//24981863
chr14:105270008-105270009(+) m6A 3'UTR       25456834//24981863
chr14:105270084-105270085(+) m6A 3'UTR       24981863
chr14:105270137-105270138(+) m6A 3'UTR       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
ZBTB42
Chromatin K562 cells     -
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: ZBTB42

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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