Basic Information:

  VIRBase ID:  

HHID00099602

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:  MIMAT0027574          SFT2D2:  NM_199344     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-6836-5p	SFT2D2
miRBase Accession/Entrez ID	MIMAT0027574	375035
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	dJ747L4.C1.2//UNQ512

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-6836-5p	rs1175923434 chr7:2257551    A/T rs1397797431 chr7:2257557    G/T rs1402374487 chr7:2257560    C/T rs373301992 chr7:2257555    C/T rs751019973 chr7:2257572    G/A rs751019973 chr7:2257572    G/T rs752401585 chr7:2257559    G/A rs752401585 chr7:2257559    G/C rs762697510 chr7:2257562    A/T rs765066033 chr7:2257558    C/A rs765066033 chr7:2257558    C/T rs767238780 chr7:2257563    G/A rs767238780 chr7:2257563    G/T rs776617786 chr7:2257553    G/A rs776617786 chr7:2257553    G/T rs1378787511 chr7:2257565    G/A rs747250755 chr7:2257571    C/CT rs756757197 chr7:2257570    G/A rs768462924 chr7:2257568    C/G rs780841384 chr7:2257571    C/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SFT2D2	chr1:168209989(+) A-I      intronic chr1:168209897(+) A-I      intronic chr1:168209990(+) A-I      intronic chr1:168209896(+) A-I      intronic chr1:168209948(+) A-I      intronic chr1:168209964(+) A-I      intronic chr1:168209991(+) A-I      intronic chr1:168210515(+) A-I      intronic chr1:168209889(+) A-I      intronic chr1:168209230(+) A-I      intronic chr1:168209260(+) A-I      intronic chr1:168196157(+) A-I      intronic chr1:168209894(+) A-I      intronic chr1:168209256(+) A-I      intronic chr1:168209158(+) A-I      intronic chr1:168196184(+) A-I      intronic chr1:168196170(+) A-I      intronic chr1:168196158(+) A-I      intronic chr1:168209254(+) A-I      intronic chr1:168207645(+) A-I      intronic chr1:168209998(+) A-I      intronic chr1:168209259(+) A-I      intronic chr1:168209253(+) A-I      intronic chr1:168209994(+) A-I      intronic chr1:168209992(+) A-I      intronic chr1:168210000(+) A-I      intronic chr1:168209427(+) A-I      intronic chr1:168209884(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SFT2D2	chr1:168196066(+) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SFT2D2	chr1:168195306-168195307(+) m6A 5'UTR//exon       24284625//25456834//24981863//22608085 chr1:168195321-168195322(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chr1:168195332-168195333(+) m1A CDS//exon       26863196 chr1:168195351-168195352(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chr1:168195360-168195361(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chr1:168205963-168205964(+) m6A CDS//exon       24284625 chr1:168211817-168211818(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr1:168211831-168211832(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr1:168211854-168211855(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr1:168211869-168211870(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr1:168211913-168211914(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr1:168211954-168211955(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr1:168212070-168212071(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr1:168212164-168212165(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr1:168212255-168212256(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr1:168212274-168212275(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr1:168214406-168214407(+) m6A 3'UTR       24981863 chr1:168214442-168214443(+) m6A 3'UTR       24981863 chr1:168221522-168221523(+) m6A 3'UTR       24981863//26404942 chr1:168221532-168221533(+) m6A 3'UTR       24981863//26404942 chr1:168221543-168221544(+) m6A 3'UTR       24981863//26404942 chr1:168221567-168221568(+) m6A 3'UTR       24284625//24981863//26404942 chr1:168221580-168221581(+) m6A 3'UTR       24284625//24981863//26404942 chr1:168221611-168221612(+) m6A 3'UTR       24284625//24981863//26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-6836-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	SFT2D2	Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-6836-5p
Interactor2: SFT2D2

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Downregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.