Detail Information

Basic Information:


  VIRBase ID:  

HHID00099601

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           RAB43:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p RAB43
miRBase
Accession/Entrez ID		 MIMAT0027574 339122
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - RAB11B//RAB41

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RAB43
chr3:128813595(-) A-I      intronic
chr3:128830275(-) A-I      intronic
chr3:128813589(-) A-I      intronic
chr3:128828784(-) A-I      intronic
chr3:128828909(-) A-I      intronic
chr3:128829492(-) A-I      intronic
chr3:128830192(-) A-I      intronic
chr3:128831003(-) A-I      intronic
chr3:128830335(-) A-I      intronic
chr3:128830338(-) A-I      intronic
chr3:128834581(-) A-I      intronic
chr3:128834577(-) A-I      intronic
chr3:128832762(-) A-I      intronic
chr3:128832740(-) A-I      intronic
chr3:128832177(-) A-I      intronic
chr3:128832147(-) A-I      intronic
chr3:128811891(-) A-I      intronic
chr3:128811972(-) A-I      intronic
chr3:128811949(-) A-I      intronic
chr3:128812016(-) A-I      intronic
chr3:128813594(-) A-I      intronic
chr3:128813566(-) A-I      intronic
chr3:128813565(-) A-I      intronic
chr3:128813541(-) A-I      intronic
chr3:128813506(-) A-I      intronic
chr3:128812053(-) A-I      intronic
chr3:128812370(-) A-I      intronic
chr3:128812341(-) A-I      intronic
chr3:128812331(-) A-I      intronic
chr3:128812321(-) A-I      intronic
chr3:128812313(-) A-I      intronic
chr3:128812210(-) A-I      intronic
chr3:128812104(-) A-I      intronic
chr3:128812664(-) A-I      intronic
chr3:128812013(-) A-I      intronic
chr3:128812007(-) A-I      intronic
chr3:128811994(-) A-I      intronic
chr3:128811990(-) A-I      intronic
chr3:128812022(-) A-I      intronic
chr3:128831769(-) A-I      intronic
chr3:128813496(-) A-I      intronic
chr3:128831770(-) A-I      intronic
chr3:128813633(-) A-I      intronic
chr3:128813641(-) A-I      intronic
chr3:128818032(-) A-I      intronic
chr3:128818113(-) A-I      intronic
chr3:128818135(-) A-I      intronic
chr3:128818338(-) A-I      intronic
chr3:128818397(-) A-I      intronic
chr3:128818406(-) A-I      intronic
chr3:128822455(-) A-I      intronic
chr3:128822477(-) A-I      intronic
chr3:128822504(-) A-I      intronic
chr3:128824367(-) A-I      intronic
chr3:128824590(-) A-I      intronic
chr3:128828064(-) A-I      intronic
chr3:128828089(-) A-I      intronic
chr3:128828131(-) A-I      intronic
chr3:128828134(-) A-I      intronic
chr3:128828177(-) A-I      intronic
chr3:128818031(-) A-I      intronic
chr3:128828190(-) A-I      intronic
chr3:128830910(-) A-I      intronic
chr3:128830979(-) A-I      intronic
chr3:128828475(-) A-I      intronic
chr3:128828484(-) A-I      intronic
chr3:128831692(-) A-I      intronic
chr3:128830976(-) A-I      intronic
chr3:128812768(-) A-I      intronic
chr3:128817784(-) A-I      intronic
chr3:128832682(-) A-I      intronic
chr3:128828800(-) A-I      intronic
chr3:128831016(-) A-I      intronic
chr3:128834078(-) A-I      intronic
chr3:128819827(-) A-I      intronic
chr3:128817768(-) A-I      intronic
chr3:128830840(-) A-I      intronic
chr3:128828975(-) A-I      intronic
chr3:128828931(-) A-I      intronic
chr3:128824252(-) A-I      intronic
chr3:128832213(-) A-I      intronic
chr3:128832279(-) A-I      intronic
chr3:128831754(-) A-I      intronic
chr3:128828462(-) A-I      intronic
chr3:128832758(-) A-I      intronic
chr3:128824164(-) A-I      intronic
chr3:128831776(-) A-I      intronic
chr3:128812270(-) A-I      intronic
chr3:128818099(-) A-I      intronic
chr3:128824213(-) A-I      intronic
chr3:128832146(-) A-I      intronic
chr3:128824592(-) A-I      intronic
chr3:128830113(-) A-I      intronic
chr3:128812092(-) A-I      intronic
chr3:128817698(-) A-I      intronic
chr3:128828911(-) A-I      intronic
chr3:128831046(-) A-I      intronic
chr3:128818422(-) A-I      intronic
chr3:128828974(-) A-I      intronic
chr3:128832212(-) A-I      intronic
chr3:128812681(-) A-I      intronic
chr3:128831797(-) A-I      intronic
chr3:128832280(-) A-I      intronic
chr3:128812353(-) A-I      intronic
chr3:128817875(-) A-I      intronic
chr3:128817792(-) A-I      intronic
chr3:128828903(-) A-I      intronic
chr3:128817869(-) A-I      intronic
chr3:128811939(-) A-I      intronic
chr3:128828750(-) A-I      intronic
chr3:128832173(-) A-I      intronic
chr3:128824123(-) A-I      intronic
chr3:128811752(-) A-I      intronic
chr3:128818075(-) A-I      intronic
chr3:128811950(-) A-I      intronic
chr3:128817733(-) A-I      intronic
chr3:128830101(-) A-I      intronic
chr3:128819842(-) A-I      intronic
chr3:128818073(-) A-I      intronic
chr3:128817794(-) A-I      intronic
chr3:128831691(-) A-I      intronic
chr3:128828476(-) A-I      intronic
chr3:128818461(-) A-I      intronic
chr3:128828335(-) A-I      intronic
chr3:128831654(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RAB43
chr3:128806830-128806831(-) m6A 3'UTR       -
chr3:128806875-128806876(-) m6A 3'UTR       -
chr3:128806948-128806949(-) m6A 3'UTR       27773535//27371828
chr3:128806953-128806954(-) m6A 3'UTR       27773535//27371828
chr3:128806988-128806989(-) m6A 3'UTR       27773535//27371828
chr3:128807068-128807069(-) m6A 3'UTR       27773535//27371828
chr3:128807075-128807076(-) m6A 3'UTR       27371828
chr3:128809349-128809350(-) m6A 3'UTR       24981863
chr3:128809385-128809386(-) m6A 3'UTR       24284625//24981863
chr3:128809424-128809425(-) m6A 3'UTR       24284625//25456834//24981863//27371828
chr3:128809477-128809478(-) m6A 3'UTR       24284625//25456834//24981863//27371828
chr3:128809485-128809486(-) m6A 3'UTR       24284625//25456834//24981863//27371828
chr3:128809918-128809919(-) m6A 3'UTR       25456834//24981863//27371828
chr3:128809969-128809970(-) m6A 3'UTR//CDS       25456834//24981863//27371828
chr3:128809978-128809979(-) m6A 3'UTR//CDS       25456834//24981863//27371828
chr3:128810176-128810177(-) m6A 3'UTR//CDS       24284625
chr3:128810185-128810186(-) m6A 3'UTR//CDS       24284625
chr3:128811398-128811399(-) m6A CDS//intron       24284625
chr3:128813998-128813999(-) m6A CDS       27371828
chr3:128840214-128840215(-) m6A CDS       27371828
chr3:128840303-128840304(-) m6A CDS       24209618//27371828//27773536
chr3:128840568-128840569(-) m6A 5'UTR//intron       25456834//27371828
chr3:128840621-128840622(-) m6A 5'UTR//intron       25456834//27371828
chr3:128840644-128840645(-) m6A 5'UTR//intron       25456834//27371828
chr3:128840757-128840758(-) m6A 5'UTR//intron       25456834//27371828
chr3:128841497-128841498(-) m6A 5'UTR       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
RAB43
Chromatin K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: RAB43

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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