Detail Information

Basic Information:


  VIRBase ID:  

HHID00099597

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           TMEM201:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p TMEM201
miRBase
Accession/Entrez ID		 MIMAT0027574 199953
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - Ima1//NET5//SAMP1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TMEM201
chr1:9659574(+) A-I      intronic
chr1:9660798(+) A-I      intronic
chr1:9659495(+) A-I      intronic
chr1:9659445(+) A-I      intronic
chr1:9659478(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TMEM201
chr1:9659495(+) A-G intron -    22484847
chr1:9660798(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TMEM201
chr1:9656965-9656966(+) m6A CDS       -
chr1:9657066-9657067(+) m6A CDS       24284625
chr1:9658612-9658613(+) m6A CDS       24284625
chr1:9658671-9658672(+) m6A CDS       24284625
chr1:9661269-9661270(+) m6A CDS       24284625
chr1:9662227-9662228(+) m6A CDS       24284625//25456834
chr1:9662362-9662363(+) m6A 3'UTR//intron       24284625//25456834//24981863
chr1:9664076-9664077(+) m6A 3'UTR//intron       24284625
chr1:9664783-9664784(+) m6A 3'UTR//intron       24284625
chr1:9664841-9664842(+) m6A 3'UTR//intron       24981863
chr1:9673208-9673209(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr1:9673266-9673267(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr1:9673284-9673285(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr1:9673309-9673310(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr1:9673744-9673745(+) m6A 3'UTR       24284625
chr1:9673911-9673912(+) m6A 3'UTR       24284625//25456834
chr1:9673954-9673955(+) m6A 3'UTR       24284625//25456834//24981863
chr1:9674004-9674005(+) m6A 3'UTR       24284625//25456834//24981863
chr1:9674043-9674044(+) m6A 3'UTR       24284625//25456834//24981863
chr1:9674141-9674142(+) m6A 3'UTR       24284625
chr1:9674194-9674195(+) m6A 3'UTR       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
TMEM201
Chromatin K562 cells     -
Cytosol HeLa-S3 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: TMEM201

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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