Detail Information

Basic Information:


  VIRBase ID:  

HHID00099587

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           JDP2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p JDP2
miRBase
Accession/Entrez ID		 MIMAT0027574 122953
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - JUNDM2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR JDP2
chr14:75932997(+) A-I      intronic
chr14:75933023(+) A-I      intronic
chr14:75933001(+) A-I      intronic
chr14:75932991(+) A-I      intronic
chr14:75933050(+) A-I      intronic
chr14:75932098(+) A-I      intronic
chr14:75932093(+) A-I      intronic
chr14:75932174(+) A-I      intronic
chr14:75932177(+) A-I      intronic
chr14:75932979(+) A-I      intronic
chr14:75932268(+) A-I      intronic
chr14:75933024(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase JDP2
chr14:75904645-75904646(+) m6A CDS//exon       24284625
chr14:75904790-75904791(+) m6A CDS//exon       22575960
chr14:75911809-75911810(+) m6A exon//intron       24981863//22575960
chr14:75911824-75911825(+) m6A exon//intron       24981863
chr14:75911860-75911861(+) m6A exon//intron       24981863
chr14:75911955-75911956(+) m6A exon//intron       24981863
chr14:75928171-75928172(+) m6A CDS       24284625//24209618//24981863
chr14:75928198-75928199(+) m6A CDS       24284625//24209618//24981863
chr14:75928200-75928201(+) Am CDS       -
chr14:75936009-75936010(+) m6A CDS       24284625//24209618//24981863
chr14:75936031-75936032(+) m6A CDS       24284625//24209618//24981863//22608085
chr14:75936083-75936084(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr14:75936112-75936113(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr14:75936127-75936128(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr14:75936172-75936173(+) m1A CDS       26863196
chr14:75936282-75936283(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr14:75936333-75936334(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr14:75936373-75936374(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr14:75936383-75936384(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr14:75936396-75936397(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr14:75936455-75936456(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr14:75936540-75936541(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr14:75936548-75936549(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr14:75936597-75936598(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr14:75936609-75936610(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr14:75936825-75936826(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr14:75936998-75936999(+) m6A 3'UTR       24284625
chr14:75938384-75938385(+) m6A 3'UTR       25456834
chr14:75938408-75938409(+) m6A 3'UTR       25456834
chr14:75938413-75938414(+) m6A 3'UTR       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
JDP2
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: JDP2

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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