Detail Information

Basic Information:


  VIRBase ID:  

HHID00099586

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           ANKRD9:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p ANKRD9
miRBase
Accession/Entrez ID		 MIMAT0027574 122416
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ANKRD9
chr14:102972169-102972170(-) m6A 3'UTR       -
chr14:102972365-102972366(-) m6A 3'UTR       -
chr14:102972424-102972425(-) m6A 3'UTR       -
chr14:102972770-102972771(-) m6A 3'UTR       -
chr14:102972832-102972833(-) m6A 3'UTR       -
chr14:102972928-102972929(-) m6A 3'UTR       -
chr14:102972950-102972951(-) m6A 3'UTR       -
chr14:102973016-102973017(-) m6A 3'UTR       -
chr14:102973047-102973048(-) m6A 3'UTR       -
chr14:102973235-102973236(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr14:102973240-102973241(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr14:102973291-102973292(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr14:102973432-102973433(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr14:102973528-102973529(-) m6A CDS       24209618//25456834//24981863//27371828//27773536//22575960
chr14:102973780-102973781(-) m6A CDS       24209618//25456834//24981863//27371828//27773536//22575960
chr14:102974815-102974816(-) m6A 5'UTR       27773536
chr14:102974837-102974838(-) m6A 5'UTR       24284625
chr14:102974862-102974863(-) m6A 5'UTR       24284625
chr14:102975046-102975047(-) m6A 5'UTR//intron       -
chr14:102975064-102975065(-) m6A 5'UTR//intron       -
chr14:102975195-102975196(-) m6A 5'UTR//intron       24284625
chr14:102975210-102975211(-) m6A 5'UTR//intron       24284625
chr14:102975287-102975288(-) m6A 5'UTR//intron       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
ANKRD9
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus K562 cells     -
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: ANKRD9

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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