Detail Information

Basic Information:


  VIRBase ID:  

HHID00099584

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           RHPN1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p RHPN1
miRBase
Accession/Entrez ID		 MIMAT0027574 114822
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ODF5//RHOPHILIN//RHPN

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RHPN1
chr8:144451033-144451034(+) m6A 5'UTR       -
chr8:144451133-144451134(+) m6A 5'UTR       -
chr8:144457828-144457829(+) m6A CDS//exon       -
chr8:144458804-144458805(+) m6A CDS//exon       -
chr8:144459592-144459593(+) m6A CDS//exon       -
chr8:144459605-144459606(+) m6A CDS//exon       -
chr8:144460874-144460875(+) m6A CDS//exon       -
chr8:144461191-144461192(+) m6A CDS//exon       24284625
chr8:144461508-144461509(+) m6A CDS//exon       24284625
chr8:144461532-144461533(+) m6A CDS//exon       24284625
chr8:144461637-144461638(+) m6A CDS//exon       24284625
chr8:144462028-144462029(+) m6A CDS//exon       -
chr8:144462073-144462074(+) m6A CDS//exon       -
chr8:144463841-144463842(+) m6A CDS//exon       24284625
chr8:144464041-144464042(+) m6A CDS//exon       24284625
chr8:144464125-144464126(+) m6A CDS//exon       24284625
chr8:144464609-144464610(+) m6A CDS//exon       24284625
chr8:144464674-144464675(+) m6A CDS//exon       24284625
chr8:144464743-144464744(+) m6A CDS//exon       24284625//24981863
chr8:144464897-144464898(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144464964-144464965(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144464973-144464974(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144465162-144465163(+) m6A 3'UTR//exon       24284625
chr8:144465266-144465267(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144465287-144465288(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144465307-144465308(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144465362-144465363(+) m6A 3'UTR//exon       24284625//24981863//22608085
chr8:144465701-144465702(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144465730-144465731(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144465744-144465745(+) m6A 3'UTR//exon       24284625//25456834//24981863//27371828//22608085
chr8:144465767-144465768(+) m6A 3'UTR//exon       24284625//25456834//24981863//27371828//22608085
chr8:144465896-144465897(+) m6A 3'UTR//exon       24284625//25456834//24981863//27371828//27773536//22608085
chr8:144466006-144466007(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085
chr8:144466041-144466042(+) m6A 3'UTR//exon       24284625//25456834//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
RHPN1
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: RHPN1

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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