Detail Information

Basic Information:


  VIRBase ID:  

HHID00099582

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           TIGD5:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p TIGD5
miRBase
Accession/Entrez ID		 MIMAT0027574 84948
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TIGD5
chr8:144680251-144680252(+) m6A CDS       25456834//24981863//22608085
chr8:144680851-144680852(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr8:144680917-144680918(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr8:144680968-144680969(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr8:144680998-144680999(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr8:144681190-144681191(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr8:144681252-144681253(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr8:144681350-144681351(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144681412-144681413(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144681439-144681440(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144681469-144681470(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144681547-144681548(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144681819-144681820(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144681861-144681862(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144681883-144681884(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144681889-144681890(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr8:144682049-144682050(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085
chr8:144682277-144682278(+) m6A 3'UTR       24284625
chr8:144682361-144682362(+) m6A 3'UTR       24284625
chr8:144682785-144682786(+) m6A 3'UTR       -
chr8:144682904-144682905(+) m6A 3'UTR       -
chr8:144682924-144682925(+) m6A 3'UTR       -
chr8:144683558-144683559(+) m6A 3'UTR       25456834//24981863//22608085
chr8:144683589-144683590(+) m6A 3'UTR       25456834//24981863//22608085
chr8:144683636-144683637(+) m6A 3'UTR       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
TIGD5
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: TIGD5

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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