Detail Information

Basic Information:


  VIRBase ID:  

HHID00099581

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           FIBCD1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p FIBCD1
miRBase
Accession/Entrez ID		 MIMAT0027574 84929
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FIBCD1
chr9:133802097(-) A-I      intronic
chr9:133787837(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FIBCD1
chr9:133778141-133778142(-) m6A 3'UTR       24284625
chr9:133778202-133778203(-) m6A 3'UTR       24284625//24209618
chr9:133778219-133778220(-) m6A 3'UTR       24284625//24209618
chr9:133778296-133778297(-) m6A 3'UTR       24284625//24209618
chr9:133778312-133778313(-) m6A 3'UTR       24284625//24209618//25456834
chr9:133778325-133778326(-) m6A 3'UTR       24284625//24209618//25456834
chr9:133778356-133778357(-) m6A 3'UTR       24284625//24209618//25456834
chr9:133778362-133778363(-) m6A 3'UTR       24284625//25456834
chr9:133778398-133778399(-) m6A 3'UTR       24284625//25456834
chr9:133778508-133778509(-) m6A 3'UTR       24284625
chr9:133778601-133778602(-) m6A 3'UTR       24284625
chr9:133778813-133778814(-) m6A 3'UTR       24284625
chr9:133778833-133778834(-) m6A 3'UTR       24284625
chr9:133778930-133778931(-) m6A 3'UTR       24284625
chr9:133779057-133779058(-) m6A 3'UTR       24284625//25456834
chr9:133779075-133779076(-) m6A 3'UTR       24284625//25456834
chr9:133779204-133779205(-) m6A 3'UTR       24284625//24209618//25456834
chr9:133779349-133779350(-) m6A 3'UTR//CDS       24284625//24209618//25456834
chr9:133779449-133779450(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863
chr9:133779457-133779458(-) m6A CDS       24284625//24209618//25456834//24981863
chr9:133779515-133779516(-) m6A CDS//intron       24284625//25456834//24981863
chr9:133779640-133779641(-) m6A CDS//intron       24284625
chr9:133779664-133779665(-) m6A CDS//intron       24284625
chr9:133780673-133780674(-) m6A CDS//intron       24284625
chr9:133780736-133780737(-) m6A CDS//intron       24284625
chr9:133780745-133780746(-) m6A CDS//intron       24284625
chr9:133787243-133787244(-) m6A CDS       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
FIBCD1
Exosome Blood     -
Nucleus HeLa-S3 cells     -
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: FIBCD1

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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