Detail Information

Basic Information:


  VIRBase ID:  

HHID00099579

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           VANGL1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p VANGL1
miRBase
Accession/Entrez ID
MIMAT0027574 81839
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - KITENIN//LPP2//STB2//STBM2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR VANGL1
chr1:116238436(+) A-I      3'UTR
chr1:116224285(+) A-I      intronic
chr1:116231597(+) A-I      intronic
chr1:116224275(+) A-I      intronic
chr1:116231634(+) A-I      intronic
chr1:116231619(+) A-I      intronic
chr1:116216495(+) A-I      intronic
chr1:116230490(+) A-I      intronic
chr1:116230432(+) A-I      intronic
chr1:116229327(+) A-I      intronic
chr1:116197088(+) A-I      intronic
chr1:116230515(+) A-I      intronic
chr1:116204507(+) A-I      intronic
chr1:116229325(+) A-I      intronic
chr1:116237239(+) A-I      3'UTR
chr1:116217907(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED VANGL1
chr1:116237239(+) A-I intron -    21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase VANGL1
chr1:116184671-116184672(+) m6A 5'UTR       24981863
chr1:116194099-116194100(+) m6A CDS       24981863
chr1:116202268-116202269(+) m6A CDS       24284625//24981863
chr1:116202279-116202280(+) m6A CDS       24284625//24981863
chr1:116202379-116202380(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr1:116206299-116206300(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr1:116206348-116206349(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr1:116206369-116206370(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr1:116206378-116206379(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr1:116206436-116206437(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr1:116206553-116206554(+) m6A CDS       24284625//24209618//24981863//22608085
chr1:116206575-116206576(+) m6A CDS       24284625//24209618//24981863//22608085
chr1:116206705-116206706(+) m6A CDS       24284625//24209618
chr1:116206714-116206715(+) m6A CDS       24284625//24209618
chr1:116225030-116225031(+) Y CDS//exon       26075521
chr1:116227999-116228000(+) m6A CDS       24284625//24209618
chr1:116228080-116228081(+) m6A CDS       24284625//24209618//24981863//22608085
chr1:116233791-116233792(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr1:116233884-116233885(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr1:116233947-116233948(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr1:116233988-116233989(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr1:116234110-116234111(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr1:116234223-116234224(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr1:116234267-116234268(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr1:116234370-116234371(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085
chr1:116234381-116234382(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22575960//22608085
chr1:116234406-116234407(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr1:116234615-116234616(+) m6A 3'UTR       24284625
chr1:116235034-116235035(+) m6A 3'UTR       24284625
chr1:116235039-116235040(+) m6A 3'UTR       24284625
chr1:116235130-116235131(+) m6A 3'UTR       24284625
chr1:116235195-116235196(+) m6A 3'UTR       24284625//24981863
chr1:116235273-116235274(+) m6A 3'UTR       24284625//24981863
chr1:116235318-116235319(+) m6A 3'UTR       25456834
chr1:116235397-116235398(+) m6A 3'UTR       25456834
chr1:116235451-116235452(+) m6A 3'UTR       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
VANGL1
Chromatin K562 cells     -
Cytosol K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: VANGL1

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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