Basic Information:

  VIRBase ID:  

HHID00099575

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:  MIMAT0027574          SLC2A11:  NM_001282864     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-6836-5p	SLC2A11
miRBase Accession/Entrez ID	MIMAT0027574	66035
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	GLUT10//GLUT11

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-6836-5p	rs1175923434 chr7:2257551    A/T rs1397797431 chr7:2257557    G/T rs1402374487 chr7:2257560    C/T rs373301992 chr7:2257555    C/T rs751019973 chr7:2257572    G/A rs751019973 chr7:2257572    G/T rs752401585 chr7:2257559    G/A rs752401585 chr7:2257559    G/C rs762697510 chr7:2257562    A/T rs765066033 chr7:2257558    C/A rs765066033 chr7:2257558    C/T rs767238780 chr7:2257563    G/A rs767238780 chr7:2257563    G/T rs776617786 chr7:2257553    G/A rs776617786 chr7:2257553    G/T rs1378787511 chr7:2257565    G/A rs747250755 chr7:2257571    C/CT rs756757197 chr7:2257570    G/A rs768462924 chr7:2257568    C/G rs780841384 chr7:2257571    C/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SLC2A11	chr22:24230306(+) A-I      intronic chr22:24230301(+) A-I      intronic chr22:24206527(+) A-I      intronic chr22:24206553(+) A-I      intronic chr22:24206623(+) A-I      intronic chr22:24206690(+) A-I      intronic chr22:24231110(+) A-I      intronic chr22:24231038(+) A-I      intronic chr22:24229457(+) A-I      intronic chr22:24229327(+) A-I      intronic chr22:24227813(+) A-I      intronic chr22:24227797(+) A-I      intronic chr22:24222284(+) A-I      intronic chr22:24222260(+) A-I      intronic chr22:24217047(+) A-I      intronic chr22:24216819(+) A-I      intronic chr22:24216615(+) A-I      intronic chr22:24214417(+) A-I      intronic chr22:24213608(+) A-I      intronic chr22:24213448(+) A-I      intronic chr22:24208999(+) A-I      intronic chr22:24208985(+) A-I      intronic chr22:24208875(+) A-I      intronic chr22:24207535(+) A-I      intronic chr22:24207054(+) A-I      intronic chr22:24201865(+) A-I      intronic chr22:24207040(+) A-I      intronic chr22:24216591(+) A-I      intronic chr22:24227491(+) A-I      3'UTR chr22:24227635(+) A-I      3'UTR chr22:24227383(+) A-I      3'UTR chr22:24230341(+) A-I      intronic chr22:24229348(+) A-I      intronic chr22:24222278(+) A-I      intronic chr22:24222223(+) A-I      intronic chr22:24231113(+) A-I      intronic chr22:24205914(+) A-I      intronic chr22:24229362(+) A-I      intronic chr22:24230271(+) A-I      intronic chr22:24208106(+) A-I      intronic chr22:24227808(+) A-I      intronic chr22:24229436(+) A-I      intronic chr22:24222325(+) A-I      intronic chr22:24230222(+) A-I      intronic chr22:24221569(+) A-I      intronic chr22:24229485(+) A-I      intronic chr22:24231133(+) A-I      intronic chr22:24221529(+) A-I      intronic chr22:24231079(+) A-I      intronic chr22:24222252(+) A-I      intronic chr22:24230295(+) A-I      intronic chr22:24221555(+) A-I      intronic chr22:24230595(+) A-I      intronic chr22:24227796(+) A-I      intronic chr22:24221523(+) A-I      intronic chr22:24229349(+) A-I      intronic chr22:24227378(+) A-I      3'UTR chr22:24227467(+) A-I      3'UTR chr22:24227704(+) A-I      3'UTR chr22:24227476(+) A-I      3'UTR chr22:24227630(+) A-I      3'UTR chr22:24227651(+) A-I      3'UTR chr22:24227357(+) A-I      3'UTR chr22:24227382(+) A-I      3'UTR chr22:24227348(+) A-I      3'UTR chr22:24227376(+) A-I      3'UTR chr22:24227271(+) A-I      3'UTR chr22:24227435(+) A-I      3'UTR chr22:24227629(+) A-I      3'UTR chr22:24227468(+) A-I      3'UTR chr22:24227306(+) A-I      3'UTR chr22:24227395(+) A-I      3'UTR chr22:24227285(+) A-I      3'UTR chr22:24227340(+) A-I      3'UTR chr22:24227339(+) A-I      3'UTR chr22:24207109(+) A-I      intronic chr22:24214385(+) A-I      intronic chr22:24221512(+) A-I      intronic chr22:24230499(+) A-I      intronic chr22:24222305(+) A-I      intronic chr22:24212944(+) A-I      intronic chr22:24214341(+) A-I      intronic chr22:24230314(+) A-I      intronic chr22:24229302(+) A-I      intronic chr22:24222366(+) A-I      intronic chr22:24221595(+) A-I      intronic chr22:24229432(+) A-I      intronic chr22:24229371(+) A-I      intronic chr22:24222272(+) A-I      intronic chr22:24208849(+) A-I      intronic chr22:24227733(+) A-I      intronic chr22:24208163(+) A-I      intronic chr22:24202774(+) A-I      intronic chr22:24221517(+) A-I      intronic chr22:24230230(+) A-I      intronic chr22:24208958(+) A-I      intronic chr22:24229423(+) A-I      intronic chr22:24222311(+) A-I      intronic chr22:24206086(+) A-I      intronic chr22:24229794(+) A-I      intronic chr22:24221644(+) A-I      intronic chr22:24222389(+) A-I      intronic chr22:24229484(+) A-I      intronic chr22:24222459(+) A-I      intronic chr22:24227730(+) A-I      intronic chr22:24206712(+) A-I      intronic chr22:24202450(+) A-I      intronic chr22:24227786(+) A-I      intronic chr22:24222288(+) A-I      intronic chr22:24221636(+) A-I      intronic chr22:24202731(+) A-I      intronic chr22:24222392(+) A-I      intronic chr22:24229902(+) A-I      intronic chr22:24222361(+) A-I      intronic chr22:24230302(+) A-I      intronic chr22:24229323(+) A-I      intronic chr22:24213343(+) A-I      intronic chr22:24221536(+) A-I      intronic chr22:24215638(+) A-I      intronic chr22:24222320(+) A-I      intronic chr22:24222441(+) A-I      intronic chr22:24231092(+) A-I      intronic chr22:24221582(+) A-I      intronic chr22:24208162(+) A-I      intronic chr22:24201815(+) A-I      intronic chr22:24227731(+) A-I      intronic chr22:24211425(+) A-I      intronic chr22:24222200(+) A-I      intronic chr22:24202973(+) A-I      intronic chr22:24212984(+) A-I      intronic chr22:24202586(+) A-I      intronic chr22:24229249(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SLC2A11	chr22:24224078(+) A-I intron -    22327324 chr22:24221471(+) A-G intron -    22484847 chr22:24222272(+) A-G intron -    22484847 chr22:24225602(+) A-G intron -    22484847 chr22:24227348(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SLC2A11	chr22:24199018-24199019(+) m6A 5'UTR       24284625//25456834//24981863//27371828//22608085 chr22:24199061-24199062(+) m6A 5'UTR       25456834//27371828//22608085 chr22:24199102-24199103(+) m6A 5'UTR       25456834//24981863//27371828//22608085 chr22:24199174-24199175(+) m6A 5'UTR//CDS//exon       25456834//24981863//22608085 chr22:24199242-24199243(+) m6A 5'UTR//exon//intron       22608085 chr22:24200153-24200154(+) m6A 5'UTR//exon//intron       24981863 chr22:24200161-24200162(+) m6A 5'UTR//exon//intron       24981863 chr22:24219340-24219341(+) m6A 3'UTR//CDS//exon       22575960 chr22:24219352-24219353(+) m6A 3'UTR//CDS//exon       22575960 chr22:24223794-24223795(+) m6A exon//intron       27773535 chr22:24223902-24223903(+) m6A exon//intron       27773535 chr22:24223908-24223909(+) m6A exon//intron       27773535 chr22:24223926-24223927(+) m6A exon//intron       27773535 chr22:24223946-24223947(+) m6A exon//intron       27773535 chr22:24223962-24223963(+) m6A exon//intron       27773535 chr22:24223974-24223975(+) m6A exon//intron       24284625//25456834//27773535 chr22:24223992-24223993(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224014-24224015(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224030-24224031(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224038-24224039(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224056-24224057(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224076-24224077(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224092-24224093(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224100-24224101(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224118-24224119(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224140-24224141(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224166-24224167(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224184-24224185(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224206-24224207(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224218-24224219(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224226-24224227(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224254-24224255(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224272-24224273(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224284-24224285(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224302-24224303(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224322-24224323(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224336-24224337(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224344-24224345(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224362-24224363(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224384-24224385(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224402-24224403(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224410-24224411(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224438-24224439(+) m6A exon//intron       24284625//25456834//27773535//22608085 chr22:24224456-24224457(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224468-24224469(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224486-24224487(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224504-24224505(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224520-24224521(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224532-24224533(+) m6A exon//intron       24284625//25456834//27773535 chr22:24224593-24224594(+) m6A exon//intron       24284625 chr22:24226919-24226920(+) m6A 3'UTR//CDS//exon       24981863 chr22:24226931-24226932(+) m6A 3'UTR//CDS//exon       24981863 chr22:24226963-24226964(+) m6A 3'UTR//CDS//exon       24284625//25456834//24981863 chr22:24227029-24227030(+) m6A 3'UTR//CDS//exon       24284625//25456834//24981863 chr22:24227710-24227711(+) Y 3'UTR//exon       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-6836-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	SLC2A11	Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-6836-5p
Interactor2: SLC2A11

Evidence Support:

Weak-Evidence	Illumina sequencing
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32223537	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Calu-3 cells	Interactor2 expression	Downregulation
Description	The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.