Detail Information

Basic Information:


  VIRBase ID:  

HHID00099574

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           LYNX1:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p LYNX1
miRBase
Accession/Entrez ID		 MIMAT0027574 66004
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED LYNX1
chr8:143853021(-) A-I exon 3'UTR    19478186

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LYNX1
chr8:143854790-143854791(-) m6A 3'UTR//intron       25456834
chr8:143854905-143854906(-) m6A 3'UTR//intron       25456834//24981863
chr8:143854929-143854930(-) m6A 3'UTR//intron       25456834
chr8:143854990-143854991(-) m6A 3'UTR//intron       25456834
chr8:143855433-143855434(-) m6A 3'UTR//intron       -
chr8:143855443-143855444(-) m6A 3'UTR//intron       -
chr8:143855557-143855558(-) m6A 3'UTR//intron       25456834
chr8:143855696-143855697(-) m6A 3'UTR//intron       25456834//24981863
chr8:143855725-143855726(-) m6A 3'UTR//intron       25456834//24981863
chr8:143856157-143856158(-) m6A 3'UTR//intron       25456834
chr8:143856190-143856191(-) m6A 3'UTR//intron       25456834
chr8:143856443-143856444(-) m6A 3'UTR//intron       25456834//24981863//22575960
chr8:143856458-143856459(-) m6A 3'UTR//intron       25456834//24981863//22575960
chr8:143856543-143856544(-) m6A 3'UTR//intron       25456834//24981863//22575960
chr8:143856557-143856558(-) m6A 3'UTR//intron       25456834//24981863//22575960
chr8:143856569-143856570(-) m6A 3'UTR//intron       25456834//24981863//22575960
chr8:143857984-143857985(-) m6A 5'UTR//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
LYNX1
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: LYNX1

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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