Detail Information

Basic Information:


  VIRBase ID:  

HHID00099572

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           ENGASE:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p ENGASE
miRBase
Accession/Entrez ID		 MIMAT0027574 64772
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ENGASE
chr17:77073162(+) A-I      intronic
chr17:77072371(+) A-I      intronic
chr17:77073073(+) A-I      intronic
chr17:77073010(+) A-I      intronic
chr17:77074266(+) A-I      intronic
chr17:77072503(+) A-I      intronic
chr17:77072499(+) A-I      intronic
chr17:77073048(+) A-I      intronic
chr17:77073055(+) A-I      intronic
chr17:77074167(+) A-I      intronic
chr17:77075299(+) A-I      intronic
chr17:77074263(+) A-I      intronic
chr17:77072566(+) A-I      intronic
chr17:77073122(+) A-I      intronic
chr17:77072571(+) A-I      intronic
chr17:77072974(+) A-I      intronic
chr17:77073095(+) A-I      intronic
chr17:77072526(+) A-I      intronic
chr17:77072999(+) A-I      intronic
chr17:77072393(+) A-I      intronic
chr17:77072409(+) A-I      intronic
chr17:77074324(+) A-I      intronic
chr17:77075358(+) A-I      intronic
chr17:77073082(+) A-I      intronic
chr17:77074372(+) A-I      intronic
chr17:77074262(+) A-I      intronic
chr17:77074315(+) A-I      intronic
chr17:77075363(+) A-I      intronic
chr17:77072471(+) A-I      intronic
chr17:77073174(+) A-I      intronic
chr17:77073136(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ENGASE
chr17:77072499(+) A-G intron -    22484847
chr17:77074263(+) A-G intron -    22484847
chr17:77074266(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ENGASE
chr17:77073525-77073526(+) m1A CDS       26863196//26863410
chr17:77073533-77073534(+) m6A CDS       -
chr17:77073567-77073568(+) m6A CDS       -
chr17:77073762-77073763(+) m6A CDS       -
chr17:77073772-77073773(+) m6A CDS       -
chr17:77077022-77077023(+) m6A 3'UTR//CDS       22575960
chr17:77077137-77077138(+) m6A 3'UTR//CDS//exon       22575960
chr17:77080096-77080097(+) m6A exon//intron       -
chr17:77080101-77080102(+) m6A exon//intron       -
chr17:77080125-77080126(+) m6A exon//intron       -
chr17:77080131-77080132(+) m6A exon//intron       -
chr17:77080138-77080139(+) m6A exon//intron       -
chr17:77080270-77080271(+) m6A exon//intron       -
chr17:77082294-77082295(+) m6A 3'UTR//CDS//exon       24284625//25456834//24981863//22608085
chr17:77082508-77082509(+) m6A 3'UTR//exon       24284625//25456834
chr17:77082564-77082565(+) m6A 3'UTR//exon       24284625//24209618
chr17:77082608-77082609(+) m6A 3'UTR//exon       24284625//24209618
chr17:77082615-77082616(+) m6A 3'UTR//exon       24284625//24209618//22608085
chr17:77082738-77082739(+) m6A 3'UTR//exon       24284625//24981863//22608085
chr17:77082743-77082744(+) m6A 3'UTR//exon       24284625//24981863//22608085
chr17:77082821-77082822(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr17:77082875-77082876(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr17:77082957-77082958(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr17:77083236-77083237(+) m6A 3'UTR       24284625//24981863//22608085
chr17:77083337-77083338(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr17:77083410-77083411(+) m6A 3'UTR       24284625//24981863
chr17:77083997-77083998(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr17:77084035-77084036(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr17:77084145-77084146(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr17:77084170-77084171(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr17:77084189-77084190(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr17:77084214-77084215(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr17:77084307-77084308(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr17:77084317-77084318(+) m6A 3'UTR       24284625//25456834//24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
ENGASE
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: ENGASE

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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