Detail Information

Basic Information:


  VIRBase ID:  

HHID00099571

  Virus:  

Middle East respiratory syndrome-related coronavirus (MERS-CoV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-6836-5p:           XYLT2:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-6836-5p XYLT2
miRBase
Accession/Entrez ID		 MIMAT0027574 64132
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - PXYLT2//SOS//XT-II//XT2//xylT-II

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-6836-5p
rs1175923434 chr7:2257551    A/T
rs1397797431 chr7:2257557    G/T
rs1402374487 chr7:2257560    C/T
rs373301992 chr7:2257555    C/T
rs751019973 chr7:2257572    G/A
rs751019973 chr7:2257572    G/T
rs752401585 chr7:2257559    G/A
rs752401585 chr7:2257559    G/C
rs762697510 chr7:2257562    A/T
rs765066033 chr7:2257558    C/A
rs765066033 chr7:2257558    C/T
rs767238780 chr7:2257563    G/A
rs767238780 chr7:2257563    G/T
rs776617786 chr7:2257553    G/A
rs776617786 chr7:2257553    G/T
rs1378787511 chr7:2257565    G/A
rs747250755 chr7:2257571    C/CT
rs756757197 chr7:2257570    G/A
rs768462924 chr7:2257568    C/G
rs780841384 chr7:2257571    C/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR XYLT2
chr17:48435078(+) A-I      intronic
chr17:48435049(+) A-I      intronic
chr17:48435076(+) A-I      intronic
chr17:48440150(+) A-I      intronic
chr17:48440237(+) A-I      intronic
chr17:48427365(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase XYLT2
chr17:48431021-48431022(+) m6A CDS       24284625//24209618//25456834//24981863//27773536
chr17:48431042-48431043(+) m6A CDS       24284625//24209618//25456834//24981863//27773536
chr17:48431048-48431049(+) m6A CDS       24284625//24209618//25456834//24981863//27773536
chr17:48431219-48431220(+) m6A CDS       24284625//24209618//25456834//24981863
chr17:48431318-48431319(+) m6A CDS       24284625//24209618//25456834//24981863//22608085
chr17:48431939-48431940(+) m6A CDS       24284625
chr17:48432347-48432348(+) m6A CDS       24284625
chr17:48432377-48432378(+) m6A CDS       24284625
chr17:48433566-48433567(+) m6A CDS       24284625
chr17:48433605-48433606(+) m6A CDS       24284625
chr17:48433882-48433883(+) m6A CDS       24284625
chr17:48433920-48433921(+) m6A CDS       24284625
chr17:48433944-48433945(+) m6A CDS       24284625
chr17:48434004-48434005(+) m6A CDS       24284625
chr17:48434618-48434619(+) m6A CDS//intron       24284625//25456834
chr17:48434656-48434657(+) m6A CDS//intron       -
chr17:48434680-48434681(+) m6A 3'UTR//intron       -
chr17:48435583-48435584(+) m6A 3'UTR//CDS//intron       24284625//24981863
chr17:48435607-48435608(+) m6A 3'UTR//CDS//intron       24284625//24981863
chr17:48435750-48435751(+) m6A 3'UTR//CDS//intron       24284625//24981863//22608085
chr17:48435807-48435808(+) m6A 3'UTR//CDS//intron       24284625//24981863//22575960
chr17:48435833-48435834(+) m6A 3'UTR//CDS//intron       24284625//24209618//24981863
chr17:48435846-48435847(+) m6A 3'UTR//CDS//intron       24284625//24209618//24981863
chr17:48435884-48435885(+) m6A 3'UTR//CDS//intron       24284625//24209618
chr17:48436343-48436344(+) m6A exon//intron       24284625//24209618
chr17:48436455-48436456(+) m6A exon//intron       24284625
chr17:48437242-48437243(+) m6A exon//intron       -
chr17:48437256-48437257(+) m6A exon//intron       -
chr17:48437410-48437411(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr17:48437487-48437488(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr17:48437498-48437499(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr17:48437525-48437526(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr17:48437573-48437574(+) m6A 3'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr17:48437679-48437680(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr17:48437702-48437703(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr17:48437735-48437736(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr17:48437775-48437776(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr17:48437801-48437802(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr17:48437812-48437813(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr17:48438202-48438203(+) m6A 3'UTR//exon//intron       24284625//24981863
chr17:48438244-48438245(+) m6A 3'UTR//exon//intron       24284625//24981863
chr17:48438266-48438267(+) m6A 3'UTR//exon//intron       24284625
chr17:48438351-48438352(+) m6A 3'UTR//exon//intron       24284625
chr17:48438413-48438414(+) m6A 3'UTR//exon//intron       -
chr17:48438424-48438425(+) m6A 3'UTR//exon//intron       -
chr17:48438436-48438437(+) m6A 3'UTR//exon//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-6836-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
XYLT2
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-6836-5p
Interactor2: XYLT2

Evidence Support:


Weak-Evidence Illumina sequencing
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 32223537 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line Calu-3 cells Interactor2 expression Downregulation
Description The miRNA-mRNA pairs with strong correlations were selected for miRNA-mRNA binding site prediction using miRanda.

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